Tag Archives: infectious diseases

What Makes Ticks Tick?

Durland Fish has researched ticks and their associated diseases for decades. A professor in the Division of Epidemiology of Microbial Diseases at the Yale School of Public Health, he has, among other things, contributed to the discovery that the bacterium that causes Lyme disease has European ancestry and that the disease, once nearly eradicated in North America, roared back with reforestation. More recently he helped develop a Lyme disease “app” for the iPhone and other Apple devices that provides users with detailed information about tick populations in any given area in the United States and even comes with a video on how to safely remove a tick. He has also worked on mosquito-borne West Nile virus and dengue fever. Students selected Fish as the school’s mentor of the year in 2010. (more…)

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Number of Dead California Sea Otters Recovered in 2011 a Record High

*Evidence Builds for White Shark Factor in Otter Mortality*

SANTA CRUZ, Calif. — The California or southern sea otter (Enhydra lutris nereis) appears to be experiencing an unprecedented increase in mortality from attacks by sharks, according to federal and state scientists. 

Since 1968, biologists and veterinarians at the U.S. Geological Survey and California Department of Fish and Game have documented and examined all reported sea otter “strandings” —  counting the number of dead, sick or injured sea otters recovered along California’s coast each year. (more…)

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Why Bad Immunity Genes Survive

*Study implicates “arms race” between genes and germs*

Biologists have found new evidence of why mice, people and other vertebrate animals carry thousands of varieties of genes to make immune-system proteins named MHCs–even though some of those genes make vertebrate animals susceptible to infections and to autoimmune diseases.

“Major histocompatibility complex” (MHC) proteins are found on the surfaces of most cells in vertebrate animals. They distinguish proteins like themselves from foreign proteins, and trigger an immune response against these foreign invaders. (more…)

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Andrew Artenstein: Essential Enzymes Key to Disease, Maybe Treatments

*Proprotein convertases are enzymes that activate many essential proteins, but they are also implicated in many processes that cause disease. In a research review in the New England Journal of Medicine, Andrew Artenstein and Steven Opal argue that proprotein convertases are potentially rich targets for developing therapies.*

Most people have never heard of proprotein convertases, but the enzymes activate many proteins that are essential for life. Unfortunately, their fundamental role puts them in the middle of many processes that cause disease – not just cancer or athlerosclerosis, but both of those and Alzheimer’s and anthrax and the flu and an amazing variety of other maladies.

In a research review article appearing Dec. 29 in the New England Journal of Medicine, Andrew Artenstein, physician-in-chief in the Department of Medicine at Memorial Hospital, and Steven Opal, chief of infectious diseases at Memorial Hospital, argue that proprotein convertases (PCs) are potentially rich targets for developing therapies. Artenstein, who with Opal is on the faculty of the Warren Alpert School of Medicine, explained PCs to David Orenstein. (more…)

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New Mouthwash Targeting Harmful Bacteria May Render Tooth Decay A Thing of The Past

A new mouthwash developed by a microbiologist at the UCLA School of Dentistry is highly successful in targeting the harmful Streptococcus mutans bacteria that is the principal cause tooth decay and cavities.

In a recent clinical study, 12 subjects who rinsed just one time with the experimental mouthwash experienced a nearly complete elimination of the S. mutans bacteria over the entire four-day testing period. The findings from the small-scale study are published in the current edition of the international dental journal Caries Research. (more…)

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Human Networking Theory Gives Picture of Infectious Disease Spread

High school students’ interactions provide new look at disease transmission

Graphic showing the flu virus and its antibodies. Image credit: NIH

It’s colds and flu season, and as any parent knows, colds and flu spread like wildfire, especially through schools.

New research using human-networking theory may give a clearer picture of just how, exactly, infectious diseases such as the common cold, influenza, whooping cough and SARS can spread through a closed group of people, and even through populations at large.

With the help of 788 volunteers at a high school, Marcel Salathé, a biologist at Penn State University, developed a new technique to count the number of possible disease-spreading events that occur in a typical day.

This results are published in this week’s issue of the journal Proceedings of the National Academy of Sciences. (more…)

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Biodiversity Loss: Detrimental to Your Health

*Infectious diseases on the rise as species disappear*

Plant and animal extinctions are detrimental to your health.

That’s the conclusion of a paper published in this week’s issue of the journal Nature by scientists who studied the link between biodiversity and infectious diseases. (more…)

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