Category Archives: Science

Correct Protein Folding:

*Berkeley Lab Researchers Identify Structure of Key Control Element Behind Protein Misfolding That Can Lead to Disease*

The gold standard for nanotechnology is nature’s own proteins. These biomolecular nanomachines – macromolecules forged from peptide chains of amino acids – are able to fold themselves into a dazzling multitude of shapes and forms that enable them to carry out an equally dazzling multitude of functions fundamental to life. As important as protein folding is to virtually all biological systems, the mechanisms behind this process have remained a mystery. The fog, however, is being lifted.

A team of researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), using the exceptionally bright and powerful x-ray beams of the Advanced Light Source, have determined the crystal structure of a critical control element within chaperonin, the protein complex responsible for the correct folding of other proteins. The incorrect or “misfolding” of proteins has been linked to many diseases, including Alzheimer’s, Parkinson’s and some forms of cancer. (more…)

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Fastest Wind From Stellar Mass Black Hole Discovered

ANN ARBOR, Mich.— The fastest wind ever discovered blowing off a disk around a stellar-mass black hole has been observed by a team of astronomers that includes a University of Michigan doctoral student.

Using NASA’s Chandra X-ray Observatory, an orbiting telescope, they clocked the record-breaking super wind at about 20 million mph, or about 3 percent of the speed of light. This is nearly 10 times faster than astronomers had previously observed from a stellar-mass black hole. (more…)

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Evolution of Earliest Horses Driven by Climate Change

*The hotter it gets, the smaller the animal?*

When Sifrhippus sandae, the earliest known horse, first appeared in the forests of North America more than 50 million years ago, it would not have been mistaken for a Clydesdale.

It weighed in at around 12 pounds–and it was destined to get much smaller over the ensuing millennia.

Sifrhippus lived during the Paleocene-Eocene Thermal Maximum (PETM), a 175,000-year interval of time some 56 million years ago in which average global temperatures rose by about 10 degrees Fahrenheit. (more…)

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To Be A Scientist

How Bob Vince changed the world

Where does it begin, the act of becoming a scientist? Perhaps with a bowling ball, its finger holes packed with explosives, which when detonated, launch the ball into the air, cracking the otherwise pristine concrete walkway of your childhood home in four places, much to the consternation of your father. Or maybe with an explosion of homemade rocket fuel in your basement chemistry lab that scares your mother half to death. And all this before the troublesome teen years. (more…)

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Pregnant Primates Miscarry When New Male Enters Group

ANN ARBOR, Mich.— Pregnant female geladas show an unusually high rate of miscarriage the day after the dominant male in their group is replaced by a new male, a new University of Michigan study indicates.

The “Bruce effect” – in which pregnant females spontaneously miscarry after being exposed to an unfamiliar male – has been found repeatedly in laboratory rodents. However, no conclusive evidence for this effect had ever been demonstrated in a wild population prior to this study. Geladas are Old World monkeys that are close relatives of baboons. (more…)

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Mathematician Sees Artistic Side To Father of Computer

This year a series of events around the world will celebrate the work of Alan Turing, the father of the modern computer, as the 100th anniversary of his birthday approaches on June 23. In a book chapter that will be published later this year, mathematician Robert Soare, the founding chairman of the University of Chicago’s computer science department, will propose that Turing’s achievement was artistic as well as scientific. (more…)

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Design Eye For The Science Guy: Drop-in Clinic Helps Scientists Communicate Data

Some of the figures scientists create are stunning. Others are not – mismatched fonts, poorly aligned tables, clashing colors.  Many fall somewhere in between. A deluge of data presents a challenge to amateur designers, often resulting in a cluttered presentation that can crowd out the figure’s main message. (more…)

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