Category Archives: Science

Responding to the Radiation Threat

*Berkeley Lab Researchers Developing Promising Treatment for Safely Decontaminating Humans Exposed to Radioactive Actinides*

The New York Times recently reported that in the darkest moments of the triple meltdown last year of the Fukushima Daiichi nuclear power plant, Japanese officials considered the evacuation of the nearly 36 million residents of the Tokyo metropolitan area. The consideration of so drastic an action reflects the harsh fact that in the aftermath of a major radiation exposure event, such as a nuclear reactor accident or a “dirty bomb” terrorist attack, treatments for mass contamination are antiquated and very limited. The only chemical agent now available for decontamination – a compound known as DTPA – is a Cold War relic that must be administered intravenously and only partially removes some of the deadly actinides – the radioactive chemical elements spanning from actinium to lawrencium on the periodic table – that pose the greatest health threats. (more…)

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A Bird’s Song May Teach Us About Human Speech Disorders

*UCLA scientists identify 2,000 important genes*

Can the song of a small bird provide valuable insights into human stuttering and speech-related disorders and conditions, including autism and stroke? New research by UCLA life scientists and colleagues provides reason for optimism.

The scientists discovered that some 2,000 genes in a region of the male zebra finch’s brain known as “Area X” are significantly linked to singing. More than 1,500 genes in this region, a critical part of the bird’s song circuitry, are being reported for the first time. Previously, a group of scientists including the UCLA team had identified some 400 genes in Area X. All the genes’ levels of expression change when the bird sings. (more…)

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Human’s Oldest Ancestor Found in Burgess Shale

Pikaia is most primitive vertebrate known

Researchers from the University of Toronto, the Royal Ontario Museum (ROM) and the University of Cambridge have confirmed that a 505 million-year-old creature, found only in the Burgess Shale fossil beds in Canada’s Yoho National Park, is the most primitive known vertebrate and therefore the ancestor of all descendant vertebrates, including humans. (more…)

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In Conversation: Sir Peter Crane

Evolutionary biologist Sir Peter Crane has been dean of the Yale School of Forestry & Environmental Studies (F&ES) since 2009. A former director of Chicago’s Field Museum and chief executive of England’s Royal Botanic Gardens, Kew, he recently spoke with Yale News about F&ES’ internationalism, the role of business in environmental management, and what it was like to be knighted at Buckingham Palace, among other topics. The following is an edited version of that conversation. (more…)

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Will a Genetic Mutation Cause Trouble? Ask Spliceman

New, free Web-based software described in the journal Bioinformatics analyzes DNA sequences to determine if mutations are likely to cause errors in splicing of messenger RNA. When gene splicing goes awry, a wide variety of diseases can result.

PROVIDENCE, R.I. [Brown University] — In a brief paper in the journal Bioinformatics, Brown University researchers describe a new, freely available Web-based program called Spliceman for predicting whether genetic mutations are likely to disrupt the splicing of messenger RNA, potentially leading to disease.

“Spliceman takes a set of DNA sequences with point mutations and computes how likely these single nucleotide variants alter splicing phenotypes,” write co-authors Kian Huat Lim, a graduate student, and William Fairbrother, assistant professor of biology, in an “application note” published in advance online Feb. 10. It will appear in print in April. (more…)

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Study Shows How The Brain Responds To Deceptive Advertising

Several specific regions of our brains are activated in a two-part process when we are exposed to deceptive advertising, according to new research conducted by a North Carolina State University professor. The work opens the door to further research that could help us understand how brain injury and aging may affect our susceptibility to fraud or misleading marketing.

The study utilized functional magnetic resonance imaging (fMRI) to capture images of the brain while study participants were shown a series of print advertisements. The fMRI images allowed researchers to determine how consumers’ brains respond to potentially deceptive advertising. “We did not instruct participants to evaluate the ads. We wanted to mimic the passive exposure to advertising that we all experience every day,” says Dr. Stacy Wood, Langdon Distinguished Professor of Marketing at NC State and co-author of a paper describing the research. (more…)

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