It Takes Two to Tango: Pairs of Entwined Proteins Handle The Stress
ANN ARBOR, Mich.— Imagine two tango dancers sweeping across the dance floor and suddenly encountering a slick spot. To avoid a slip or even a nasty tumble, the pair must work together to support one another and glide safely through the stressful moment.
In a similar way, a certain type of helper protein called a stress-specific molecular chaperone prevents its client proteins from collapsing during stressful situations by uncoiling a long, supportive arm that wraps around them, a University of Michigan-led research team has shown. (more…)