Utah Team Invents Way to Image Brains of Mice Using a Small Needle
A University of Utah team discovered a method for turning a small, $40 needle into a 3-D microscope capable of taking images up to 70 times smaller than the width of a human hair. This new method not only produces high-quality images comparable to expensive microscopes, but may be implanted into the brains of living mice for imaging at the cellular level. (more…)
*Researchers have created a living 3-D model of a brain tumor and its surrounding blood vessels. In experiments, the scientists report that iron-oxide nanoparticles carrying the agent tumstatin were taken by blood vessels, meaning they should block blood vessel growth. The living-tissue model could be used to test the effectiveness of nanoparticles in fighting other diseases. Results appear in Theranostics.*
PROVIDENCE, R.I. [Brown University] — Brown University scientists have created the first three-dimensional living tissue model, complete with surrounding blood vessels, to analyze the effectiveness of therapeutics to combat brain tumors. The 3-D model gives medical researchers more and better information than Petri dish tissue cultures.
The researchers created a glioma, or brain tumor, and the network of blood vessels that surrounds it. In a series of experiments, the team showed that iron-oxide nanoparticles ferrying the chemical tumstatin penetrated the blood vessels that sustain the tumor with oxygen and nutrients. The iron-oxide nanoparticles are important, because they are readily taken up by endothelial cells and can be tracked by magnetic resonance imaging. (more…)
Looking like a pair of eyeglasses only a rock star would wear, this nebula brings into focus a murky region of star formation. NASA’s Spitzer Space Telescope exposes the depths of this dusty nebula with its infrared vision, showing stellar infants that are lost behind dark clouds when viewed in visible light.
Best known as Messier 78, the two round greenish nebulae are actually cavities carved out of the surrounding dark dust clouds. The extended dust is mostly dark, even to Spitzer’s view, but the edges show up in mid-wavelength infrared light as glowing, red frames surrounding the bright interiors. Messier 78 is easily seen in small telescopes in the constellation of Orion, just to the northeast of Orion’s belt, but looks strikingly different, with dominant, dark swaths of dust. Spitzer’s infrared eyes penetrate this dust, revealing the glowing interior of the nebulae. (more…)
The various spiral arm segments of the Sunflower galaxy, also known as Messier 63, show up vividly in this image taken in infrared light by NASA’s Spitzer Space Telescope. Infrared light is sensitive to the dust lanes in spiral galaxies, which appear dark in visible-light images. Spitzer’s view reveals complex structures that trace the galaxy’s spiral arm pattern.
Messier 63 lies 37 million-light years away — not far from the well-known Whirlpool galaxy and the associated Messier 51 group of galaxies. (more…)
