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Portable Diagnostics Designed To Be Shaken, Not Stirred

By Guest PostMay 12, 2012Scienceashutosh shastry, asymmetrical surface, audio speaker, blood, energy, hannah hickey, karl bohringer, lotus effect, lotus leaf, medical researcher, menlo park, Nanotechnology, portable diagnostics, rough surface, saliva, smartphone, todd duncombe, university of washington, vibration, vibration frequency, water sample, yegan erdem

As medical researchers and engineers try to shrink diagnostics to fit in a person’s pocket, one question is how to easily move and mix small samples of liquid.

University of Washington researchers have built and patented a surface that, when shaken, moves drops along certain paths to conduct medical or environmental tests.

“This allows us to move drops as far as we want, and in any kind of layout that we want,” said Karl Böhringer, a UW professor of electrical engineering and bioengineering. The low-cost system, published in a recent issue of the journal Advanced Materials, would require very little energy and avoids possible contamination by diluting or electrifying the samples in order to move them. (more…)

You’re Beautiful, Vesta

By Guest PostMay 11, 2012Sciencedawn mission, meteorites from vesta, mineral data, protoplanet, protoplanet vesta, vesta

NASA’s UCLA-led Dawn mission shows protoplanet’s surprising surface

When UCLA’s Christopher T. Russell looks at the images of the protoplanet Vesta produced by NASA’s Dawn mission, he talks about beauty as much as he talks about science. (more…)

UCLA Scientists Unlock Mystery of How ‘Handedness’ Arises

By Guest PostMay 10, 2012Scienceachiral building blocks, achiral objects, chirality, handedness, lithographic triangular particles, mirror image phenomenon, molecular characteristic

The overwhelming majority of proteins and other functional molecules in our bodies display a striking molecular characteristic: They can exist in two distinct forms that are mirror images of each other, like your right hand and left hand. Surprisingly, each of our bodies prefers only one of these molecular forms. (more…)

Brighter, Smaller Probes to Uncover the Secret Lives of Proteins

By Guest PostMay 10, 20121 commentSciencealexis ostrowski, andrew mueller, berkeley lab, bruce cohen, cellular mechanism, daniel gargas, delia milliron, disease, elan katz, emory chan, erbium, function, gang han, imagine tracking, james schuck, lanthanide, live cell, los angeles, molecule, nanocrystal, nanoparticle, nayf4, photobleach, protein, radio transmitter, sodium yttrium fluoride, vistamar school, wanda robot, ytterbium

Berkeley Lab scientists create nanoparticle probes that may lead to a better understanding of diseases

Imagine tracking a deer through a forest by clipping a radio transmitter to its ear and monitoring the deer’s location remotely. Now imagine that transmitter is the size of a house, and you understand the problem researchers may encounter when they try to use nanoparticles to track proteins in live cells.

Understanding how a protein moves around a cell helps researchers understand the protein’s function and the cellular mechanisms for making and processing proteins. This information also helps researchers study disease, which at a cellular level may mean that a protein is malfunctioning, stops being made, or is sent to the wrong part of the cell. But nanoparticle probes that are too big can disrupt a protein’s normal activities. (more…)

Scientists Measure Communication between Stem Cell-Derived Motor Neurons, Muscle Cells

By Guest PostMay 10, 2012Science: walking, amyotrophic lateral sclerosis, bennett g novitch, breathing, communication, electrode, genetic mutation, joy umbach, lou gehrigs disease, motor function, motor neuron, muscle cells, neurodegenerative diseases, neurological disorder, spinal muscular atrophy, synaptic activity, vitro system

In an effort to identify the underlying causes of neurological disorders that impair motor functions such as walking and breathing, UCLA researchers have developed a novel system to measure communication between stem cell–derived motor neurons and muscle cells in a Petri dish.

The study provides an important proof of principle that functional motor circuits can be created outside the body using these neurons and cells and that the level of communication, or synaptic activity, between them can be accurately measured by stimulating the motor neurons with an electrode and then tracking the transfer of electrical activity into the muscle cells to which the neurons are connected. (more…)

NASA’s Spitzer Sees the Light of Alien ‘Super Earth’

By Guest PostMay 9, 2012Science55 cancri, 55 cancri e, atmosphere, bill danchi, gaseous planet, hot jupiter, jet propulsion laboratory, kelvin, michael gillon, michael werner, NASA, planet, signs of life, solar system, spitzer project, spitzer space telescope, super earth

PASADENA, Calif. – NASA’s Spitzer Space Telescope has detected light emanating from a “super-Earth” planet beyond our solar system for the first time. While the planet is not habitable, the detection is a historic step toward the eventual search for signs of life on other planets.

“Spitzer has amazed us yet again,” said Bill Danchi, Spitzer program scientist at NASA Headquarters in Washington. “The spacecraft is pioneering the study of atmospheres of distant planets and paving the way for NASA’s upcoming James Webb Space Telescope to apply a similar technique on potentially habitable planets.” (more…)

Biologists Turn Back the Clock to Understand Evolution of Sex Differences

By Guest PostMay 9, 2012Nature, Scienceabderrahman khila, antlers, battle, darwin, ehab abouheif, evolution, hooks, locke rowe, male guppies, mating, mcgill university, moose, peacocks, plumage, rheumatobates rileyi, rna interference, sex differences, sexes, traits in nature, tusks, university of toronto, walruses, water striders, wild colours

Battles of sexes shown to spur adaptive sex differences

Sex differences account for some of the most of the spectacular traits in nature: the wild colours of male guppies, the plumage of peacocks, tusks on walruses and antlers on moose. Sexual conflict – the battle between males and females over mating – is thought to be a particularly potent force in driving the evolution of traits that differ in males and females.

However, the genetic processes responsible for producing such traits are not well understood, nor how they evolved from their simpler less elaborate ancestral forms. We tend to assume that each tiny step in evolution is an advantage. But are they really? (more…)

A NASA Weather ‘Eye in the Sky’ Marks 10 Years

By Guest PostMay 7, 2012Environment, Scienceairs, amsu a, atmosphere, atmospheric infrared sounder, bae systems, boston, carbon dioxide, climate change, climate research, earth, energy cycle, eric fetzer, eye, global water, greenhouse gases, hyperspectral sounding, instrument, jet propulsion laboratory, model, monster, moustafa chahine, NASA, sky, tom pagano, water vapor, weather forecasting, weather satellites

For 10 years, it has silently swooped through space in its orbital perch 438 miles (705 kilometers) above Earth, its nearly 2,400 spectral “eyes” peering into Earth’s atmosphere, watching. But there’s nothing alien about NASA’s Atmospheric Infrared Sounder, or AIRS, instrument, a “monster” of weather and climate research that celebrates its 10th birthday in orbit May 4.

AIRS, built by BAE Systems, Boston, under the direction of NASA’s Jet Propulsion Laboratory, Pasadena, Calif., is one of six instruments flying on NASA’s Aqua spacecraft as part of NASA’s Earth Observing System. AIRS, along with its partner microwave instrument, the Advanced Microwave Sounding Unit (AMSU-A), has faithfully measured our planet’s atmospheric temperature, water vapor, clouds and greenhouse gases with unprecedented accuracy and stability. Over the past decade, AIRS and AMSU-A have improved our understanding of Earth’s global water and energy cycles, climate change and trends and how Earth’s climate system is responding to increased greenhouse gases. (more…)

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