A brain-development gene found exclusively in humans has an unusual evolutionary history and could contribute to what makes us distinctly human. Equally surprising, this is a partial gene created from an incomplete duplication of its “parent” gene in the prehistoric human genome.
Gene duplication is an important driving force in creating physical changes in living things during evolution, explained the researchers studying the SRGAP2 gene family. Drs. Megan Dennis and Xander Nuttle, in the Howard Hughes Medicine Institute research lab of Dr. Evan Eichler, University of Washington professor of genome sciences, co-authored the report on the findings. (more…)
GAINESVILLE, Fla. — A new University of Florida study that determined the age of skeletal remains provides evidence humans reached the Western Hemisphere during the last ice age and lived alongside giant extinct mammals.(more…)
If you throw a rubber balloon filled with water against a wall, it will spread out and deform on impact, while the same balloon filled with honey, which is more viscous, will deform much less. If the balloon’s elastic rubber was stiffer, an even smaller change in shape would be observed.
By simply analyzing how much a balloon changes shape upon hitting a wall, you can uncover information about its physical properties.
Although cells are not simple sacks of fluid, they also contain viscous and elastic properties related to the membranes that surround them; their internal structural elements, such as organelles; and the packed DNA arrangement in their nuclei. Because variations in these properties can provide information about cells’ state of activity and can be indicative of diseases such as cancer, they are important to measure. (more…)
Berkeley Lab-led team explores a way to create biofuels, minus the photosynthesis
Is there a new path to biofuels hiding in a handful of dirt? Lawrence Berkeley National Laboratory (Berkeley Lab) biologist Steve Singer leads a group that wants to find out. They’re exploring whether a common soil bacterium can be engineered to produce liquid transportation fuels much more efficiently than the ways in which advanced biofuels are made today.
The scientists are working with a bacterium called Ralstonia eutropha. It naturally uses hydrogen as an energy source to convert CO2 into various organic compounds. (more…)
ANN ARBOR, Mich.— Portable gas sensors can allow you to search for explosives, diagnose medical conditions through a patient’s breath, and decide whether it’s safe to stay in a mine.(more…)
PASADENA, Calif. – Astronomers have gathered the most direct evidence yet of a supermassive black hole shredding a star that wandered too close. NASA’s Galaxy Evolution Explorer, a space-based observatory, and the Pan-STARRS1 telescope on the summit of Haleakala in Hawaii were among the first to help identify the stellar remains.
Supermassive black holes, weighing millions to billions times more than the sun, lurk in the centers of most galaxies. These hefty monsters lie quietly until an unsuspecting victim, such as a star, wanders close enough to get ripped apart by their powerful gravitational clutches. (more…)
Berkeley Lab scientists demonstrate the promise of synchrotron infrared spectroscopy of living cells for medical applications
Knowing how a living cell works means knowing how the chemistry inside the cell changes as the functions of the cell change. Protein phosphorylation, for example, controls everything from cell proliferation to differentiation to metabolism to signaling, and even programmed cell death (apoptosis), in cells from bacteria to humans. It’s a chemical process that has long been intensively studied, not least in hopes of treating or eliminating a wide range of diseases. But until now the close-up view – watching phosphorylation work at the molecular level as individual cells change over time – has been impossible without damaging the cells or interfering with the very processes that are being examined.
“To look into phosphorylation, researchers have labeled specific phosphorylated proteins with antibodies that carry fluorescent dyes,” says Hoi-Ying Holman of the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab). “That gives you a great image, but you have to know exactly what to label before you can even begin.” (more…)
