Approach borrows from technique of inhibiting protein fibers that cause Alzheimer’s and Parkinson’s diseases
UCLA scientists have developed a promising novel method to treat gynecologic tumors. The approach focuses on a protein called p53, which is commonly mutated in women who have high-grade serous ovarian cancer, the deadliest form of reproductive cancer. In many women with the disease, the cancer is very advanced by the time it is diagnosed and is therefore difficult to treat.(more…)
AUSTIN, Texas — An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this discovery by exploiting the evolutionary relatedness of yeast, frogs, mice and humans.(more…)
Yale University scientists have developed a new mechanism for attacking cancerous tumors that intensifies the body’s immune response while simultaneously weakening the tumor’s ability to resist it.
“We believe this is a paradigm-changing immunotherapeutic method for cancer therapy,” said Tarek M. Fahmy, a bioengineer at Yale and the project’s principal investigator. “In essence, it’s a one-two punch strategy that seems to work well for melanoma and may work even better with other cancers.” (more…)
Compared to normal cells, cancer cells have a prodigious appetite for glucose, the result of a shift in cell metabolism known as aerobic glycolysis or the “Warburg effect.” Researchers focusing on this effect as a possible target for cancer therapies have examined how biochemical signals present in cancer cells regulate the altered metabolic state.(more…)
UD alum and ‘Jeopardy!’ champ Craig tells students it’s important to take chances
When Li Liao, associate professor in the University of Delaware Department of Computer and Information Sciences, saw Roger Craig’s almost-perfect GRE score while Craig was applying to graduate school at UD, the faculty member said to himself, “Wow, this guy is smart.”
Liao says he took a chance on Craig, who had no formal training in computer science. Craig would go on to exceed his adviser’s expectations, studying bioinformatics and earning master’s and doctoral degrees in computer and information sciences at UD.
Craig also would set several records on the Jeopardy! quiz show in 2010 and 2011, among them, the all-time record for single-day winnings ($77,000). Craig said that when he hit the daily doubles, he almost always bet everything. (more…)
*Specialized structures used by cancer cells to invade tissues could also help them escape protection mechanisms aimed at eliminating them, a UA-led research team has discovered.*
Studying embryos of the sea squirt Ciona intestinalis, the researchers discovered that even non-invasive cells make the delicate, highly transient structures known as invadopodia. The group found that future heart cells in the Ciona embryo use invadopodia to pick up chemical signals from their surroundings. These so-called growth factors provide the cells with clues as to where they are in the developing embryo and what type of cell they are supposed to turn into. (more…)
GAINESVILLE, Fla. — When a movie character says, “It’s too quiet,” that’s usually a sign something bad may happen.
Now, University of Florida researchers have discovered that when variations of a certain protein in our cells are too quiet, it may add to the risk that someone will develop lung cancer. When scientists restored the protein to its normal, active self, its cancer-inhibiting properties reappeared. (more…)
For certain kinds of cancer, the most effective therapy does not use x-rays or gamma rays but beams of ions, the electrically charged cores of atoms, including hydrogen ions (protons) and heavier ions such as carbon and neon.(more…)
