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UCLA scientists test new strategy that could help fight ovarian cancer

Approach borrows from technique of inhibiting protein fibers that cause Alzheimer’s and Parkinson’s diseases

UCLA scientists have developed a promising novel method to treat gynecologic tumors. The approach focuses on a protein called p53, which is commonly mutated in women who have high-grade serous ovarian cancer, the deadliest form of reproductive cancer. In many women with the disease, the cancer is very advanced by the time it is diagnosed and is therefore difficult to treat. (more…)

Fat Cells in Abdomen Fuel Spread of Ovarian Cancer

By Guest PostNovember 4, 2011Health, Scienceabdominal cavity, breast cancer, cause of cancer deaths in women, energy dense lipids, ernst lengyel, fabp4, fat carrier, fat cells, fatty acid binding protein, fatty tissue, gastric and colon cancers, growth of ovarian cancer, healthy mice, hilary kenny, intestines, kristin nieman, nutrients, omentum, ovarian cancer, ovarian cancer cells, ovarian cancer metastasis, protein, protein signals, stomach, tumor cells, university of chicago

A large pad of fat cells that extends from the stomach and covers the intestines provides nutrients that promote the spread and growth of ovarian cancer, reports a University of Chicago-based research team in the journal Nature Medicine, published online Oct. 30.

Ovarian cancer, the fifth-leading cause of cancer deaths in women, tends to spread within the abdominal cavity as opposed to distant organs. In 80 percent of women, by the time ovarian cancer is diagnosed, it has spread to the pad of fat cells, called the omentum. Often, cancer growth in the omentum exceeds the growth of the original ovarian cancer. (more…)

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UCLA scientists test new strategy that could help fight ovarian cancer

Fat Cells in Abdomen Fuel Spread of Ovarian Cancer