Tag Archives: hypoxia

Everest Expedition Suggests Nitric Oxide Benefits for Intensive Care Patients

The latest results from an expedition to Mount Everest that looked at the body’s response to low oxygen levels suggest that drugs or procedures that promote the body’s production of a chemical compound called nitric oxide (NO) could improve the recovery of critically ill patients in intensive care.

Many critically ill patients suffer from a shortage of oxygen (a condition known as ‘hypoxia’), which can be life-threatening. NO is produced by virtually every cell and organ in the body where it serves many important functions including the regulation of blood pressure, learning and memory formation, and protecting us from infectious diseases. (more…)

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Researcher Aims to Improve Effectiveness of Radiation Therapy for Cancer

Sara Rockwell is a leader in her field. A professor of therapeutic radiology and pharmacology at the School of Medicine, Rockwell was among the first researchers to study the effects of oxygen deficiency on the response of malignant cells to radiation and anticancer drugs, and was among the first to consider the implications of this deficiency in microscopic tumors for the development of solid malignancies.

Rockwell, who is also associate dean for scientific affairs, joined the faculty of Yale School of Medicine in 1974, and teaches radiation biology, pharmacology, cancer biology, ethics and career development skills. She earned her bachelor’s degree in physics from Penn State University in 1965. She went on to earn her doctorate degree in biophysics from Stanford University in 1971. (more…)

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