COLUMBUS, Ohio – An abnormally low level of a protein in certain nerve cells is linked to movement problems that characterize the deadly childhood disorder spinal muscular atrophy, new research in animals suggests.
Spinal muscular atrophy, or SMA, is caused when a child’s motor neurons – nerve cells that send signals from the spinal cord to muscles – produce insufficient amounts of what is called survival motor neuron protein, or SMN. This causes motor neurons to die, leading to muscle weakness and the inability to move. (more…)
Lowering glucose levels for people with diabetes is normally critical to improving health outcomes. But for diabetes patients with heart failure, that might not always be the case, say UCLA researchers.(more…)
People who received frequent dental X-rays in the past, before dosages were lowered, have an increased risk of developing a meningioma, the most common and potentially debilitating type of non-cancerous brain tumor, a new study led by the Yale School of Public Health has found. The study is published online in Cancer, a journal of the American Cancer Society.
Meningioma is listed as a rare disease by the National Institutes of Health. The estimated incidence is up to 8 out of 100,000 people, and it occurs more frequently among women than men. Although it is the most frequently diagnosed type of brain tumor, meningioma is listed as a rare disease by the National Institutes of Health. Tumors develop in a membrane that envelops the brain and the central nervous system known as the meninges. They can grow undetected for years and eventually reach the size of a baseball or larger. While they are not cancerous, they can cause debilitating side effects such as headaches, vision problems, and loss of speech and motor control. (more…)
A wearable artificial kidney, designed as a new treatment for kidney failure, will be tested in Seattle. The trial will be done in collaboration with the Food and Drug Administration under a new Innovations Pathway announced Monday.(more…)
UD researchers develop novel technique for early detection of misfolded protein
University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in the pathogenesis, or development, of Huntington’s disease.(more…)
With technological advancements opening the door to less invasive medical procedures, robotic-assisted surgery is becoming increasingly popular, despite being more expensive than traditional surgery. Robotic-assisted surgical removal of the bladder due to cancer is a new approach to the traditional “open” — or more invasive — operation called a radical cystectomy.
Bladder cancer is the fourth most commonly diagnosed cancer in men, and the American Cancer Society estimates that 73,500 people will be diagnosed with bladder cancer in 2012. A third of those will require a radical cystectomy. (more…)
Can Inflammation Predict Heart Disease and Stroke?
Groundbreaking research may be able to help predict how likely it is that a person will have heart disease or a stroke in the future. Studies have linked inflammation to the risk of cardiovascular disease because of the association between the release of C-Reactive Protein (CRP) and heart disease.
What is C-Reactive Protein (CRP)?
The National Institute of Health explains that CRP is a protein that is released when there is inflammation present in the body. The liver produces the protein and a blood test can be done to find out how much CRP is present in a person’s body.
What is inflammation?
John W. Kimball maintains a website describing in depth how inflammation develops in the body. Inflammation develops as a result of injury to the body. It can often be recognized by swelling and redness at the site of inflammation and may be accompanied by pain. Although inflammation often occurs on the surface of the skin, it can also occur internally. (more…)
Why do some people experience post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA study may shed light on the answer.
UCLA scientists have linked two genes involved in serotonin production to a higher risk of developing PTSD. Published in the April 3 online edition of the Journal of Affective Disorders, the findings suggest that susceptibility to PTSD is inherited, pointing to new ways of screening for and treating the disorder. (more…)
