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Huntington’s Disease

By Guest PostApril 8, 2012Healthalzheimer's disease, amyloid fiber, amyloid seeding assay, asa, brain tissue, david w colby, fluorescent detector, hd, huntingtin, huntingtons disease, monomeric polyglutamine peptide, neurological disease, novel technology, prion disease, protein, sharad gupta, shyann jie, thioflavin t, university of delaware

UD researchers develop novel technique for early detection of misfolded protein

University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in the pathogenesis, or development, of Huntington’s disease.

Huntington’s disease (HD) is one of several neurological diseases, such as Alzheimer’s disease or prion disease, associated with proteins that fold into abnormal structures. HD is characterized by progressive motor impairment, cognitive decline and behavioral abnormalities, and ultimately death. (more…)

Fewer Deaths, Complications with Robotic Bladder Cancer Surgery, But Cost is Higher

By Guest PostApril 8, 2012Healthadam s kibel, bladder, bladder cancer, cancer, european urology, georgetown university hospital, hua yin yu, intravenous nutrition, jim hu, parenteral nutrition, paul l nguyen, radical cystectomy, robot, robotic assisted surgery, robotic surgery, statistical analysis

With technological advancements opening the door to less invasive medical procedures, robotic-assisted surgery is becoming increasingly popular, despite being more expensive than traditional surgery. Robotic-assisted surgical removal of the bladder due to cancer is a new approach to the traditional “open” — or more invasive — operation called a radical cystectomy.

Bladder cancer is the fourth most commonly diagnosed cancer in men, and the American Cancer Society estimates that 73,500 people will be diagnosed with bladder cancer in 2012. A third of those will require a radical cystectomy. (more…)

Can Inflammation Predict Heart Disease and Stroke?

By Guest PostApril 7, 2012Healthanti inflammatory medication, asthma, blood clots, blood test, c reactive protein, cardiovascular disease, cholesterol, chronic inflammation, crp, disease, heart attack, heart disease, inflammation, protein, stroke

Can Inflammation Predict Heart Disease and Stroke?

Groundbreaking research may be able to help predict how likely it is that a person will have heart disease or a stroke in the future. Studies have linked inflammation to the risk of cardiovascular disease because of the association between the release of C-Reactive Protein (CRP) and heart disease.

What is C-Reactive Protein (CRP)?

The National Institute of Health explains that CRP is a protein that is released when there is inflammation present in the body. The liver produces the protein and a blood test can be done to find out how much CRP is present in a person’s body.

What is inflammation?

John W. Kimball maintains a website describing in depth how inflammation develops in the body. Inflammation develops as a result of injury to the body. It can often be recognized by swelling and redness at the site of inflammation and may be accompanied by pain. Although inflammation often occurs on the surface of the skin, it can also occur internally. (more…)

UCLA Study Identifies Genes Linked to Post-Traumatic Stress Disorder

By Guest PostApril 7, 2012Healthafghanistan, alan steinberg, american, armen goenjian, danger, david walling, devon schmidt, disorder, DNA, ernest noble, flashbacks, gene, hyper alert, Iraq, julia bailey, natural disaster, post traumatic, ptsd, ptsd symptom, rape, stress disorder, symptoms, tph1, tph2, uma dandekar, variant, war, war veteran

Why do some people experience post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? A new UCLA study may shed light on the answer.

UCLA scientists have linked two genes involved in serotonin production to a higher risk of developing PTSD. Published in the April 3 online edition of the Journal of Affective Disorders, the findings suggest that susceptibility to PTSD is inherited, pointing to new ways of screening for and treating the disorder. (more…)

Oxygen in Tumours Predicts Prostate Cancer Recurrence

By Guest PostApril 5, 2012Healthgenetic signature, hypoxia in tumors, oxygen in tumours, oxygen level, prostate cancer, radiation therapy

TORONTO, ON — Low oxygen levels in tumors can be used to predict cancer recurrence in men with intermediate-risk prostate cancer even before they receive radiation therapy. (more…)

Soy and Menopause

By Guest PostApril 5, 2012Healthartika rangan casini, estrogen, frequency, genistein, hot flashes, Japan, kathy f atkinson, melissa melby, menopause, placebo, soy, soy isoflavones, soy on menopause, soy protein, soybeans, tofu, utero

*Large-scale study finds soy may alleviate hot flashes in menopause*

In the most comprehensive study to date to examine the effects of soy on menopause, researchers have found that two daily servings of soy can reduce the frequency and severity of hot flashes by up to 26 percent, compared to a placebo.

The findings, published in Menopause: The Journal of the North American Menopause Association, reviewed 19 previous studies that examined more than 1,200 women. (more…)

Seeing Double: 1 in 30 Babies Born in U.S. is a Twin

By Guest PostApril 4, 2012Healthbarbara luke, birth of twins, children, fertility therapies, fertility treatment, fetal loss, fetuses, joyce martin, medication, ovulation stimulation, reproductive technologies, twin, twin birth, united states, women

EAST LANSING, Mich. — Women having children at older ages and the growing availability of fertility treatments has led to a marked increase in the birth of twins: In 2009, one in every 30 babies born in the United States was a twin compared with one in every 53 in 1980.

The findings, presented by Michigan State University’s Barbara Luke this week at the 14th Congress of the International Society of Twin Studies in Florence, Italy, have important health implications, including greater morbidity and mortality risks and higher health care costs. (more…)

Curcumin Shows Promise in Attacking Parkinson’s Disease

By Guest PostApril 1, 2012Healthalpha synuclein protein, amino acid, basir ahmad, body temperature, clumping, curcumin, disease, folding, lisa lapidus, parkinson's, protein, spice, technique, turmeric

EAST LANSING, Mich. — Curcumin, a compound found in the spice turmeric, is proving effective at preventing clumping of a protein involved in Parkinson’s disease, says a Michigan State University researcher.

A team of researchers led by Basir Ahmad, an MSU postdoctoral researcher, demonstrated earlier this year that slow-wriggling alpha-synuclein proteins are the cause of clumping, or aggregation, which is the first step of diseases such as Parkinson’s. A new study led by Ahmad, which appears in the current issue of the Journal of Biological Chemistry, shows that curcumin can help prevent clumping. (more…)

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