Why Some Pain Drugs Become Less Effective Over Time
Researchers at the University of Montreal’s Sainte-Justine Hospital have identified how neural cells are able to build up resistance to opioid pain drugs within hours. “A better understanding of these mechanisms will enable us to design drugs that avoid body resistance to these drugs and produce longer therapeutic responses, including longer-acting opioid analgesics”, lead author Dr. Graciela Pineyro said. (more…)