Category Archives: Health

Project Aims To Improve HIV/AIDS Prevention Materials For African-American Women

African-American women make up a disproportionate number of HIV/AIDS cases in the United States. Researchers from North Carolina State University are trying to change that, leading a National Science Foundation project aimed at developing HIV/AIDS prevention materials that resonate with African-American female college students.

African-Americans represent approximately 14 percent of the U.S. population, but accounted for an estimated 44 percent of new HIV infections in 2009. The estimated rate of new HIV infections among African-American women was 15 times that of white women and over three times that of Latina women. (more…)

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How Good Cholesterol Turns Bad

Berkeley Lab Researchers Find New Evidence on How Cholesterol Gets Moved from HDLs to LDLs

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from “good” high density lipoproteins (HDLs) to “bad” low density lipoproteins (LDLs). These findings point the way to the design of safer, more effective next generation CETP inhibitors that could help prevent the development of heart disease. (more…)

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In The Mouth, Smoking Zaps Healthy Bacteria, Welcomes Pathogens

COLUMBUS, Ohio — According to a new study, smoking causes the body to turn against its own helpful bacteria, leaving smokers more vulnerable to disease.

Despite the daily disturbance of brushing and flossing, the mouth of a healthy person contains a stable ecosystem of healthy bacteria. New research shows that the mouth of a smoker is a much more chaotic, diverse ecosystem—and is much more susceptible to invasion by harmful bacteria. (more…)

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Radiation Generates Cancer Stem Cells From Less Aggressive Breast Cancer Cells

Breast cancer stem cells, thought to be the sole source of tumor recurrence, are known to be resistant to radiation therapy and don’t respond well to chemotherapy.

Now, researchers with the UCLA Department of Radiation Oncology at UCLA’s Jonsson Comprehensive Cancer Center report for the first time that radiation treatment, despite killing half of all tumor cells during every treatment, transforms other cancer cells into treatment-resistant breast cancer stem cells. (more…)

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High Population Density is Greatest Risk Factor For Water-Linked Diseases

COLUMBUS, Ohio – Water-associated infectious disease outbreaks are more likely to occur in areas where a region’s population density is growing, according to a new global analysis of economic and environmental conditions that influence the risk for these outbreaks.

Ohio State University scientists constructed a massive database containing information about 1,428 water-associated disease outbreaks that were reported between 1991 and 2008 around the world. By combining outbreak records with data on a variety of socio-environmental factors known about the affected regions, the researchers developed a model that can be used to predict risks for water-associated disease outbreaks anywhere in the world. (more…)

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When Nerve Meets Muscle, Biglycan Seals The Deal

In the absence of the protein biglycan, synapses at neuromuscular junctions in mice began to break up about five weeks after birth, according to a new study led by Brown University researchers. Reintroducing byglycan helped fix the loss of synaptic stability in cell culture. The research may be relevant to efforts to treat motor neuron diseases, such as amyotrophic lateral sclerosis (ALS, Lou Gehrig’s Disease) and spinal muscular atrophy. (more…)

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