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Huntington’s Disease

By Guest PostApril 8, 2012Healthalzheimer's disease, amyloid fiber, amyloid seeding assay, asa, brain tissue, david w colby, fluorescent detector, hd, huntingtin, huntingtons disease, monomeric polyglutamine peptide, neurological disease, novel technology, prion disease, protein, sharad gupta, shyann jie, thioflavin t, university of delaware

UD researchers develop novel technique for early detection of misfolded protein

University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in the pathogenesis, or development, of Huntington’s disease.

Huntington’s disease (HD) is one of several neurological diseases, such as Alzheimer’s disease or prion disease, associated with proteins that fold into abnormal structures. HD is characterized by progressive motor impairment, cognitive decline and behavioral abnormalities, and ultimately death. (more…)

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Huntington’s Disease