Category Archives: Science

UCLA Uses Hybrid, Precision Heart Procedures to Help Stop Deadly Arrhythmias

Hybrid Cardiac Procedure. Schematic of the heart showing the minimally-invasive approaches to allow access to the surface of the heart (the blue and red areas) during this hybrid cardiac procedure. Image credit: University of California

New techniques now being used at UCLA allow doctors to more precisely target certain areas of the heart to stop ventricular arrhythmias — serious abnormal rhythms in the heart’s lower chambers — in high-risk patients.

 

Generally, arrhythmias can be controlled by medications, and sometimes defibrillators. But a potentially life-threatening, recurrent arrhythmia known as a ventricular tachycardia, which originates in one of the heart’s two ventricles, can produce a fast heart beat that requires other interventions, such as catheter ablation, in which the precise focus area of the arrhythmia must be controlled. 

Cardiologists will often use catheter ablation once medications and other therapies have failed. The procedure involves the insertion of a tiny, metal-tipped catheter through a vein in the groin or neck to reach the inside of the heart. Prior to the procedure, electrical tests are conducted on the heart to identify and map the exact site of the arrhythmia’s origin.  (more…)

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Low Blood Levels of Vitamin D Linked to Chubbier Kids, Faster Weight Gain

ANN ARBOR, Mich.—Kids who are deficient in vitamin D accumulated fat around the waist and gained weight more rapidly than kids who got enough vitamin D, a new University of Michigan study suggests.

Vitamin D, which is primarily provided to the body by the sun, has been a hot topic in the U.S. lately. The federal standards for vitamin D intake have come under fire by public health professionals as being much too low, and disagreement continues over the proper amount of vitamin D necessary for optimal health. (more…)

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Study Shows Extreme Form of Pregnancy-Related Morning Sickness Could be Genetic

*Pregnant women whose sisters had condition are 17 times more likely to have it*

Approximately 60,000 pregnant women are hospitalized each year due to hyperemesis gravidarum (HG), an extreme form of nausea and vomiting that endangers their lives and often forces them to reluctantly terminate their pregnancies.  

And for women with sisters, mothers and grandmothers on either side of the family who have experienced extreme morning sickness during pregnancy, the risk of HG may be heightened, according to a new study led by researchers from UCLA and the University of Southern California.  (more…)

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New 3-D Model of RNA ‘Core Domain’ of Enzyme Telomerase May Offer Clues to Cancer, Aging

A model representation of telomerase's RNA "core domain," determined by Juli Feigon, Qi Zhang and colleagues in Feigon's UCLA laboratory. Image credit: Juli Feigon, UCLA Chemistry and Biochemistry/PNAS

Telomerase is an enzyme that maintains the DNA at the ends of our chromosomes, known as telomeres. In the absence of telomerase activity, every time our cells divide, our telomeres get shorter. This is part of the natural aging process, as most cells in the human body do not have much active telomerase. Eventually, these DNA-containing telomeres, which act as protective caps at the ends of chromosomes, become so short that the cells die.

 

But in some cells, such as cancer cells, telomerase, which is composed of RNA and proteins, is highly active and adds telomere DNA, preventing telomere shortening and extending the life of the cell. 

UCLA biochemists have now produced a three-dimensional structural model of the RNA “core domain” of the telomerase enzyme. Because telomerase plays a surprisingly important role in cancer and aging, understanding its structure could lead to new approaches for treating disease, the researchers say.  (more…)

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The Genetics of Self-Incompatibility

*Petunias show that the mechanisms behind inbreeding prevention are similar to immune response*

About the image: The female part of the petunia flower secretes an enzyme that is designed to deter pollen tube growth, thereby preventing fertilization. However, in the cases that the pollen has come from a genetically different plant, the pollen produces its own protein that combats the pistil’s enzyme. With the enzyme out of the way, the pollen tube can keep growing and fertilization can occur. Image credit: Zina Deretsky, National Science Foundation

Inbreeding is a bad strategy for any organism, producing weak and problematic offspring. So imagine the challenge of inbreeding prevention in a plant where male and female sexual organs grow right next to each other! Such is the genetic conundrum faced by the petunia. (more…)

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Scientists to Spy on People’s Dreams and Thoughts

Image credit: Wikipedia

Until now it was believed that a person is unable to read the thoughts of fellow human beings. “Spying” on the dreams of another person appeared unrealistic. However, recent research by American scientists revealed that both these things are quite possible. Overly complex devices and paranormal abilities are not required to do so.

Recently, a respectable scientific journal Nature published an article that ten years ago would have been considered a fiction and would not have been publication at all. A group of American researchers led by Dr. Moran Cerf claims to have found a way to electronically records and decipher human dreams and thoughts. No complicated devices are required. The entire transcript can successfully go through an electroencephalograph – a device that for decades has been used by neuroscientists around the world. (more…)

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Cosmic Curiosity Reveals Ghostly Glow of Dead Quasar

The green Voorwerp in the foreground remains illuminated by light emitted up to 70,000 years ago by a quasar in the center of the background galaxy, which has since died out. Image credit: WIYN/William Keel/Anna Manning

While sorting through hundreds of galaxy images as part of the Galaxy Zoo citizen science project two years ago, Dutch schoolteacher and volunteer astronomer Hanny van Arkel stumbled upon a strange-looking object that baffled professional astronomers. Two years later, a team led by Yale University researchers has discovered that the unique object represents a snapshot in time that reveals surprising clues about the life cycle of black holes.

In a new study, the team has confirmed that the unusual object, known as Hanny’s Voorwerp (Hanny’s “object” in Dutch), is a large cloud of glowing gas illuminated by the light from a quasar-an extremely energetic galaxy with a supermassive black hole at its center. The twist, described online in the Astrophysical Journal Letters, is that the quasar lighting up the gas has since burned out almost entirely, even though the light it emitted in the past continues to travel through space, illuminating the gas cloud and producing a sort of “light echo” of the dead quasar. (more…)

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Better Weather: Water-vapor Profiling System Could Result in More Accurate, Less Costly Forecasting

A vehicle from the National Severe Storms Laboratory observes conditions around a tornado in Wyoming during June of 2009. Image credit: Mike Coniglio, NOAA/NSSL

Researchers at the Georgia Institute of Technology and Bennett Aerospace are leveraging light detection and ranging (lidar) technology to develop a ground-based system that will automatically measure water vapor in the atmosphere. Known as”WaV-ProTM,” for Water Vapor Profiler, the system aims to provide more frequent data collection that could dramatically improve weather forecasting.

Initial work on the project began in mid-2009, when Bennett Aerospace, in collaboration with the Georgia Tech Research Institute (GTRI), won a Phase I Small Business Innovation Research grant from the National Oceanic and Atmospheric Administration (NOAA) to develop design requirements for the system. Recently, the researchers won a Phase II grant to build and test critical components needed for a final operating prototype of WaV-Pro. (more…)

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