Tag Archives: degenerative diseases

What Do Animals ‘Know’? More Than You May Think

Rats use their knowledge to make decisions when faced with ambiguous situations, UCLA psychologists report.

“Rats often make judgments and behave as if they’re rational creatures,” said UCLA associate professor of psychology Aaron Blaisdell, a member of UCLA’s Brain Research Institute and senior author of a new study published in the December issue of the journal Psychonomic Bulletin and Review.

“To make a decision in the face of uncertainty, rats call on prior history and reasoning,” Blaisdell said. “They apply what they know to a situation where they are uncertain. The rats are not necessarily thinking like little humans, but they have learned through experience. A lot of animal behavior seems to be rational. Their behavior follows logical inferences.” (more…)

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U-M Researchers Identify Protein Essential for Cell Division in Blood-forming Stem Cells

ANN ARBOR, Mich.— University of Michigan researchers have discovered that a protein known to regulate cellular metabolism is also necessary for normal cell division in blood-forming stem cells. Loss of the protein results in an abnormal number of chromosomes and a high rate of cell death. 

The finding demonstrates that stem cells are metabolically different from other blood-forming cells, which can divide without the protein, Lkb1. This metabolic difference could someday be used to better control the behavior of blood-forming stem cells used in disease treatments, said Sean Morrison, director of the U-M Center for Stem Cell Biology, which is based at the Life Sciences Institute.  (more…)

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