Category Archives: Science

Neurons that Control Overeating also Drive Appetite for Cocaine

Researchers at Yale School of Medicine have zeroed in on a set of neurons in the part of the brain that controls hunger, and found that these neurons are not only associated with overeating, but also linked to non-food associated behaviors, like novelty-seeking and drug addiction.

Published in the June 24 online issue of Nature Neuroscience, the study was led by Marcelo O. Dietrich, postdoctoral associate, and Tamas L. Horvath, the Jean and David W. Wallace Professor of Biomedical Research and chair of comparative medicine at Yale School of Medicine.

In attempts to develop treatments for metabolic disorders such as obesity and diabetes, researchers have paid increasing attention to the brain’s reward circuits located in the midbrain, with the notion that in these patients, food may become a type of “drug of abuse” similar to cocaine. Dietrich notes, however, that this study flips the common wisdom on its head. (more…)

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Water in a Changing World

Experimental watershed provides new insights, rich educational experience

Six years and about 4,000 water samples later, an outdoor experimental watershed laboratory established by University of Delaware faculty members Shreeram Inamdar and Delphis Levia at Fair Hill, Md., is now producing valuable data and novel insights into how water and chemicals move through the forest canopy, soils and watersheds, and how future climate change may impact or alter such responses.

Inamdar, associate professor in the Department of Plant and Soil Sciences, has investigated the role of soils, streams, and watersheds in leaching water and nutrients, while Levia, professor in the Department of Geography, has studied the interactions of atmosphere and the forest canopy in leaching water and nutrients. Together, they have provided a complete picture of watershed hydrology and biogeochemistry. (more…)

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Lariats: How RNA Splicing Decisions are Made

Lariats are discarded byproducts of RNA splicing, the process by which genetic instructions for making proteins are assembled. A new study has found hundreds more lariats than ever before, yielding new information about how splicing occurs and how it can lead to disease

PROVIDENCE, R.I. [Brown University] — Tiny, transient loops of genetic material, detected and studied by the hundreds for the first time at Brown University, are providing new insights into how the body transcribes DNA and splices (or missplices) those transcripts into the instructions needed for making proteins. (more…)

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Researchers Find Gold Nanoparticles Capable of ‘Unzipping’ DNA

New research from North Carolina State University finds that gold nanoparticles with a slight positive charge work collectively to unravel DNA’s double helix. This finding has ramifications for gene therapy research and the emerging field of DNA-based electronics.

“We began this work with the goal of improving methods of packaging genetic material for use in gene therapy,” says Dr. Anatoli Melechko, an associate professor of materials science and engineering at NC State and co-author of a paper describing the research. Gene therapy is an approach for addressing certain medical conditions by modifying the DNA in relevant cells. (more…)

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Combating Global Problems at BIARI

Some 140 participants and 30 visiting faculty from more than 45 countries arrived at Brown to take part in the Brown International Advanced Research Institutes (BIARI). The two-week program began June 11, 2012

PROVIDENCE, R.I. [Brown University] — Some 140 participants and 30 visiting faculty from more than 45 countries arrived at Brown to take part in the Brown International Advanced Research Institutes (BIARI). Participants, who were chosen from a pool of more than 850 applicants, come from several countries, including Brazil, China, Nigeria, India, and Ethiopia. (more…)

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Childhood Obesity Linked to Math Performance, MU Researcher Says

COLUMBIA, Mo. – Childhood obesity has increased dramatically throughout the past 40 years and has been tied to many health problems. Now, a University of Missouri researcher has found that children’s weight is associated with their math performance.

“The findings illustrate the complex relationships among children’s weight, social and emotional well-being, academics and time,” said Sara Gable, associate professor in the MU Department of Nutrition and Exercise Physiology, who led the study.

Gable looked at more than 6,250 children from the Early Childhood Longitudinal Study-Kindergarten Cohort, a nationally representative sample. The children were followed from the time they started kindergarten through fifth grade. At five points in time, parents provided information about their families, teachers reported on the children’s interpersonal skills and emotional well-being, and children were weighed and measured; they also took academic tests. (more…)

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Scientists Reconstruct Pre-Columbian Human Effects on the Amazon Basin

Findings overturn idea that the Amazon had large populations of humans that transformed the landscape

Small, shifting human populations existed in the Amazon before the arrival of Europeans, with little long-term effect on the forest.

That’s the result of research led by Crystal McMichael and Mark Bush of the Florida Institute of Technology (FIT). The finding overturns the idea the Amazon was a cultural parkland in pre-Columbian times with large human populations that transformed vast tracts of the landscape.

The Amazon Basin is one of the highest biodiversity areas on Earth. Understanding how it was modified by humans in the past is important for conservation and for understanding the ecological processes in tropical rainforests. (more…)

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