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Natural Compound Mitigates Effects of Methamphetamine Abuse, University of Missouri Researchers Find

By Guest PostNovember 26, 2013Healthalzheimer's disease, behavioral impairments, bond life, brain, colored vegetables, dennis miller, disease research, dopamine level, drug addiction, effects, grace y sun, hyperactivity, methamphetamine abuse, mizzou advantage, model, natural compound, neurodegenerative disorders, neurological, neurotransmitter dopamine, parkinsons disease, resveratrol containing products, sciences center, stroke, sustainable energy, university of missouri

COLUMBIA, Mo. – Studies have shown that resveratrol, a natural compound found in colored vegetables, fruits and especially grapes, may minimize the impact of Parkinson’s disease, stroke and Alzheimer’s disease in those who maintain healthy diets or who regularly take resveratrol supplements. Now, researchers at the University of Missouri have found that resveratrol may also block the effects of the highly addictive drug, methamphetamine.

Dennis Miller, associate professor in the Department of Psychological Sciences in the College of Arts & Science and an investigator with the Bond Life Sciences Center, and researchers in the Center for Translational Neuroscience at MU, study therapies for drug addiction and neurodegenerative disorders. Their research targets treatments for methamphetamine abuse and has focused on the role of the neurotransmitter dopamine in drug addiction. Dopamine levels in the brain surge after methamphetamine use; this increase is associated with the motivation to continue using the drug, despite its adverse consequences. However, with repeated methamphetamine use, dopamine neurons may degenerate causing neurological and behavioral impairments, similar to those observed in people with Parkinson’s disease. (more…)

UCLA doctors test stem-cell therapy to improve blood flow in angina patients

By Guest PostNovember 24, 2013Healthali nsair, angina patients, angioplasty, blood flow, cd34 protein, coronary bypass, heart attack, heart in 3d, heart muscle, heart transplant, jonathan tobis, las vegas, marty greenfield, phase 3, pluripotent cell, rubine gevorgyan, stem cell injection, stem cell therapy, ucla doctors, william suh

Clinical trial evaluates treatment for patients who haven’t responded to other FDA–approved procedures

Marty Greenfield lives with crushing pain every day due to angina, a condition that is caused by an inadequate supply of blood to the heart. He has suffered a heart attack, and a coronary bypass procedure and angioplasty have provided little relief. His doctor referred him to UCLA to be considered for a heart transplant.

Dr. Jonathan Tobis, a UCLA clinical professor of cardiology, performed an angiogram and angioplasty on Greenfield, 64, but found that the patient was not a candidate for a heart transplant because his heart muscle function was still good. (more…)

Society for Neuroscience 2013: How sleep aids visual task learning

By Guest PostNovember 22, 2013Health, Sciencebrainwaves, brown university, david orenstein, decline of function, due to aging, electronic encephalography, ji won bang, magnetic resonance imaging, measure the brainwaves, neural mechanism, neural oscillations, playing the piano, polysomnography, psychological sciences, san diego, sigma brainwave, sigma frequency, sleep, sleeping brain, society for neuroscience, supplementary motor area, Takeo Watanabe, visual cortical area, visual task learning, yuka sasaki

At the Society for Neuroscience annual meeting in San Diego Nov. 10, 2013, Brown University scientists presented research showing what happens in the brain during sleep to lock in learning of a visually oriented “Where’s Waldo”-like task.

PROVIDENCE, R.I. [Brown University] — As any indignant teacher would scold, students must be awake to learn. But what science is showing with increasing sophistication is how the brain uses sleep for learning as well. At the annual meeting of the Society for Neuroscience in San Diego Nov. 10, 2013, Brown University researchers discussed new research describing the neural mechanism by which the sleeping brain locks in learning of a visual task. (more…)

Tomato therapy: Engineered veggies target intestinal lipids, improve cholesterol

By Guest PostNovember 19, 2013Healthatherosclerosis, cholesterol levels, clogged arteries, engineered tomatoes, systemic inflammation, tomato therapy

UCLA researchers report that tiny amounts of a specific type of lipid in the small intestine may play a greater role than previously thought in generating the high cholesterol levels and inflammation that lead to clogged arteries.
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Cause of genetic disorder found in “dark matter” of DNA

By Guest PostNovember 18, 2013Healthblood, cause, cell, dark matter, disease, DNA, genetic disorder, glucose, junk dna, mike weedon, pancreatic agenesis, pancreatic beta cells, professor andrew hattersley, ptf1a regulatory region, regulating level, sugar, type 1 diabetes, university of exeter

For the first time, scientists have used new technology which analyses the whole genome to find the cause of a genetic disease in what was previously referred to as “junk DNA”.

Pancreatic agenesis results in babies being born without a pancreas, leaving them with a lifetime of diabetes and problems digesting food.

In a breakthrough for genetic research, teams led by the University of Exeter Medical School and Imperial College London found that the condition is most commonly caused by mutations in a newly identified gene regulatory element in a remote part of the genome, which can now be explored thanks to advances in genetic sequencing. (more…)

Personal reflection triggers increased brain activity during depressive episode

By Guest PostNovember 17, 2013Healthanxiety, brain imaging technology, british queen, depression, depressive episode, fmri, frontal cortex, increased brain activity, laura parkes, may sarsam, neuroimaging, personal reflection, peter kinderman, psychological theory, university of liverpool, university of manchester

Research by the Universities of Liverpool and Manchester has found that people experiencing depressive episodes display increased brain activity when they think about themselves.

Using functional magnetic resonance imaging (fMRI) brain imaging technologies, scientists found that people experiencing a depressive episode process information about themselves in the brain differently to people who are not depressed.

Researchers scanned the brains of people in major depressive episodes and those that weren’t whilst they chose positive, negative and neutral adjectives to describe either themselves or the British Queen – a figure significantly removed from their daily lives but one that all participants were familiar with. (more…)

The science of living better, longer

By Guest PostNovember 16, 2013Healthaging process, better health, disease modifying therapy, quality of life, risk of falling, science of living

Did you ever wonder what science is doing to help us age more comfortably, in better health, doing the things we care about, for a longer span of time? (more…)

Experimental drug shows encouraging results in treating most common form of lung cancer

By Guest PostNovember 15, 2013Healthamerican cancer society, australia, common form, drug related, edward garon, experimental drug, immunotherapy drug, kill cancer cell, lung cancer, merck, mk 3475, new drug, phase 1b study, protein pd1, side effects, sydney, treating, ucla, world conference

An experimental cancer drug that has shown promise in the treatment of melanoma has also shown early potential as an effective treatment for patients with non-small cell lung cancer, the leading cause of cancer death among men and women worldwide.

Dr. Edward Garon, director of thoracic oncology at UCLA’s Jonsson Comprehensive Cancer Center, presented the preliminary results of a Phase 1B study of the new drug, called MK-3475, on Oct. 29 at the World Conference on Lung Cancer in Sydney, Australia. (more…)

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