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Breast screening: The new high-tech, simpler approach

By Guest PostNovember 5, 2013Health2d mammography, 2d synthetic mammography, 3d data, 3d mammography, 3d screening, assessment, breast center, breast screening, diagnostic radiologist, high tech, journal radiology, liane philpotts, lumpectomy, mammography, radiologist

In two years, 3D screening has picked up more early cancers than mammography while cutting down on the number of callbacks. One radiologist calls it “a game changer.”

October 2013) No woman wants to get a call that her radiologist has found a suspicious image on her mammogram, and then learn that she might need a biopsy—only to find out it was all a false alarm. Now, thanks to new technology, fewer women will get those calls.

Digital breast tomosynthesis, or 3-D mammography, is transforming breast screening by significantly reducing callbacks while picking up more cancers, and eliminating some of the fear and anxiety many women experience. All women who visit the Breast Center at Smilow Cancer Hospital at Yale-New Haven for mammography are now getting tomosynthesis over plain 2D mammography, says Liane Philpotts, MD, chief of breast imaging for the Breast Center. (more…)

Left-handed people more likely to have psychotic disorders such as schizophrenia: Yale Study

By Guest PostNovember 2, 2013Healthbiomarker, bipolar syndrome, christopher chee, deanna dial, depression, hussam jefee, left handed people, mary i schroeder, michael helfenbein, psychosis, psychotic disorders, rebecca hana, schizophrenia, us population

Being left-handed has been linked to many mental disorders, but Yale researcher Jadon Webb and his colleagues have found that among those with mental illnesses, people with psychotic disorders like schizophrenia are much more likely to be left-handed than those with mood disorders like depression or bipolar syndrome.

The new study is published in the October-December 2013 issue of the journal SAGE Open. (more…)

UCLA scientist uncovers biological clock able to measure age of most human tissues

By Guest PostNovember 1, 2013Health, Scienceage, age predictive tool, biological clock, cancer, cancer in women, chronological age, dna methylation levels, embryonic stem cell, genome biology, hormones, human aging process, human tissues, saliva, stem cell research, steve horvath, telomeres, ucla scientist

Study finds women’s breast tissue ages faster than the rest of the body

Everyone grows older, but scientists don’t really understand why. Now a UCLA study has uncovered a biological clock embedded in our genomes that may shed light on why our bodies age and how we can slow the process.

Published in the Oct. 21 edition of the journal Genome Biology, the findings could offer valuable insights to benefit cancer and stem cell research. (more…)

UW work contributes to largest international study of Alzheimer’s genes

By Guest PostOctober 31, 2013Healthalzheimer's disease, alzheimers genes, amyloid precursor protein, annette fitzpatrick, autoimmune disorder, brain cell, bruce psaty, cell migration, cognitive decline, debby tsuang, gene, genomics of alzheimer, inflammation, international study, joshua bis, lipid transport, multiple sclerosis, neurodegenerative disease, paul k crane, tau protein

Eleven regions of the human genome have been newly discovered to influence the onset of Alzheimer’s disease. The findings stem from the largest international study ever conducted on this disorder, which causes gradual memory loss and other forms of cognitive decline in older people.

As of 2009, 10 genes were known to be related to Alzheimer’s, the result of about a quarter-century of research. Yet the reasons behind individual susceptibility or resistance to the disease continued to be poorly understood. In February of 2011, four international research groups studying Alzheimer’s disease genetics united to more quickly identify other genes related to the disorder. (more…)

Grandson of first chemotherapy doctor now teaches at Yale School of Medicine

By Guest PostOctober 28, 2013Healthchemical weapons, first chemotherapy doctor, guided treatments, gustaf lindskog, lymphocidal chemical, nitrogen mustard, thoracic surgeon

When Dr. Dieter Lindskog first began walking the halls of Yale School of Medicine a decade ago, people would stop him often to ask, “Are you by any chance related to …?” Now they stop him rarely, either because they know the answer or are too young to recognize the famous name — that of the grandfather who upended accepted tenets of medical practice and, in doing so, gave birth to the science and art of modern oncology. (more…)

Small bits of genetic material fight cancer’s spread

By Guest PostOctober 25, 2013Healthbone fracture, bone lesions, bone metastasis, brian ell, cancer, class of molecules, combat, david waning, disease, extreme pain, gene, genetic material, Germany, hamburg, indiana university, indianapolis, khalid mohammad, micrornas, nerve compression, pathological activity, predictors of metastasis, princeton university, therapeutic target, theresa guise, university cancer center, yibin kang

A class of molecules called microRNAs may offer cancer patients two ways to combat their disease.

Researchers at Princeton University have found that microRNAs — small bits of genetic material capable of repressing the expression of certain genes — may serve as both therapeutic targets and predictors of metastasis, or a cancer’s spread from its initial site to other parts of the body. The research was published in the journal Cancer Cell. (more…)

One in 2,000 of UK population carries variant CJD proteins

By Guest PostOctober 17, 2013Healthabnormal prion protein, degenerative brain disease, mad cow disease, prion protein

One in 2,000 people in the UK are estimated to be carrying variant Creutzfeldt-Jakob disease (vCJD) proteins, according to a study led by Professor Sebastian Brandner (UCL Institute of Neurology). (more…)

Scientists Cooking Up Alloy “Recipes” For Bone Implants

By Guest PostOctober 17, 2013Health, Sciencealloy recipes, armed with microscopes, bone, bone implants, computer simulations, general electric, hamish fraser, ji cheng, niobium, ohio state university, President Obama, strain, stress, tantalum, titanium, united states, zhao

Project will utilize Ohio State’s new microscopy facility

COLUMBUS, Ohio — Armed with microscopes, computers and an innovative way to study metals, researchers at The Ohio State University and their partners are building a database of new titanium alloys.

The goal: to reduce the stress that pins, plates and other medical implants put on healthy bones. (more…)

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