bone metastasis – Shamskm: A site to exchange knowledge and solutions

Small bits of genetic material fight cancer’s spread

By Guest PostOctober 25, 2013Healthbone fracture, bone lesions, bone metastasis, brian ell, cancer, class of molecules, combat, david waning, disease, extreme pain, gene, genetic material, Germany, hamburg, indiana university, indianapolis, khalid mohammad, micrornas, nerve compression, pathological activity, predictors of metastasis, princeton university, therapeutic target, theresa guise, university cancer center, yibin kang

A class of molecules called microRNAs may offer cancer patients two ways to combat their disease.

Researchers at Princeton University have found that microRNAs — small bits of genetic material capable of repressing the expression of certain genes — may serve as both therapeutic targets and predictors of metastasis, or a cancer’s spread from its initial site to other parts of the body. The research was published in the journal Cancer Cell. (more…)

Prostate Cancer Spreads to Bones by Overtaking The Home of Blood Stem Cells

ANN ARBOR, Mich.— Like bad neighbors who decide to go wreck another community, prostate and breast cancer usually recur in the bone, according to a new University of Michigan study.

Now, U-M researchers believe they know why. Prostate cancer cells specifically target and eventually overrun the bone marrow niche, a specialized area for hematopoietic stem cells, which make red and white blood cells, said Russell Taichman, professor at the U-M School of Dentistry and senior author of the study. (more…)

Tag Archives: bone metastasis

Small bits of genetic material fight cancer’s spread

Prostate Cancer Spreads to Bones by Overtaking The Home of Blood Stem Cells