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Breast screening: The new high-tech, simpler approach

In two years, 3D screening has picked up more early cancers than mammography while cutting down on the number of callbacks. One radiologist calls it “a game changer.”

October 2013) No woman wants to get a call that her radiologist has found a suspicious image on her mammogram, and then learn that she might need a biopsy—only to find out it was all a false alarm. Now, thanks to new technology, fewer women will get those calls.

Digital breast tomosynthesis, or 3-D mammography, is transforming breast screening by significantly reducing callbacks while picking up more cancers, and eliminating some of the fear and anxiety many women experience. All women who visit the Breast Center at Smilow Cancer Hospital at Yale-New Haven for mammography are now getting tomosynthesis over plain 2D mammography, says Liane Philpotts, MD, chief of breast imaging for the Breast Center. (more…)

Fat cells in breast may connect social stress to breast cancer

By Guest PostJune 23, 2013Healthacaca, acetyl coa carboxykase, acly, aggressive breast cancer, antigen mice, atp citrate lyase, breast, carcinoma in situ, chronic stress, erin wonder, estrogen, fat cells, female mice, gene, her2, hexokinase, hk2, hormones, leptin, lumpectomy, mammary fat, mammary glands, martha mcclintock, matthew brady, maxwell skor, metabolism, metabolism of glucose, multiple tissues, paul volden, progesterone, receptor, social stress, suzanne conzen, sv40 t, triple negative, tumor growth, tumors, university of chicago

Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research.

Some forms of stress exposure may be associated with an increased risk of certain types of aggressive breast cancer. But the mechanisms linking the biology of social stress to cancer have been hard to identify. To unravel that mechanism, the researchers looked for differences between mice raised in small groups and those that grow up in an isolated setting—an established model of chronic stress without social supports. (more…)

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Breast screening: The new high-tech, simpler approach

Fat cells in breast may connect social stress to breast cancer