Yale University scientists have developed a new mechanism for attacking cancerous tumors that intensifies the body’s immune response while simultaneously weakening the tumor’s ability to resist it.
“We believe this is a paradigm-changing immunotherapeutic method for cancer therapy,” said Tarek M. Fahmy, a bioengineer at Yale and the project’s principal investigator. “In essence, it’s a one-two punch strategy that seems to work well for melanoma and may work even better with other cancers.” (more…)
In new study published in PNAS, scientists found that nanoparticles, produced from chemicals in tea, reduced tumors by 80 percent
COLUMBIA, Mo. – Currently, large doses of chemotherapy are required when treating certain forms of cancer, resulting in toxic side effects. The chemicals enter the body and work to destroy or shrink the tumor, but also harm vital organs and drastically affect bodily functions. Now, University of Missouri scientists have found a more efficient way of targeting prostate tumors by using gold nanoparticles and a compound found in tea leaves. This new treatment would require doses that are thousands of times smaller than chemotherapy and do not travel through the body inflicting damage to healthy areas. The study is being published in the Proceedings of the National Academy of Science.(more…)
A team of researchers, including Mary-Frances O’Connor at the UA, has found a genetic variability linked to stress and inflammation that may impact the health of some widows and widowers
The death of a spouse can be one of life’s most distressing events, and for many years bereavement researchers have noted increased mortality risk in some widows and widowers. This has been called the “widowhood effect.”(more…)
Findings could aid researchers in understanding progression of disease
It’s well known in conventional biology that during the process of mammalian cell division, or mitosis, a mother cell divides equally into two daughter cells. But when it comes to cancer, say UCLA researchers, mother cells may be far more prolific. (more…)
For the first time, the U.S. Food and Drug Administration is considering approving a drug that helps prevent someone from acquiring HIV. It’s called Truvada, and has been approved for use since 2004 to treat infected people.
Now it has been shown to protect healthy people who are exposed to HIV. The UW’s International Clinical Research Center, within the Department of Global Health, played a key role in examining the drug’s effectiveness for HIV prevention.
Researchers Connie Celum and Jared Baeten led a study, published this week in the New England Journal of Medicine, of pre-exposure prophylaxis among heterosexual couples in Kenya and Uganda. One partner had HIV (and was not yet eligible for HIV treatment) and the other partner did not have HIV. Uninfected partners were given either Truvada or Tenofovir (both antiretroviral drugs) or a placebo. (more…)
Copper alloys may make more hygienic cooking surfaces than stainless steel, according to a recent study by Sadhana Ravishankar of the UA department of veterinary science and microbiology. Her lab group discovered that copper alloys have antimicrobial effects against the foodborne pathogen Salmonella enterica.
Each year a tiny, rod-shaped species of bacteria with a fondness for proliferating on human food causes numerous cases of food poisoning around the world, sometimes leading to severe illness and even death.(more…)
COLUMBUS, Ohio – A new study reveals a simple strategy that people can use to minimize how angry and aggressive they get when they are provoked by others.
When someone makes you angry, try to pretend you’re viewing the scene at a distance – in other words, you are an observer rather than a participant in this stressful situation. Then, from that distanced perspective, try to understand your feelings.
Researchers call this strategy “self-distancing.” (more…)
Heart attacks during pregnancy are uncommon, but the prevalence of heart disease in pregnant mothers has increased over the past decade as more women delay pregnancy until they are older. These women, who are generally less physically active than their younger peers, tend to have higher cholesterol levels and are at greater risk of heart disease and diabetes.
While research has shown that the heart typically functions better during pregnancy due to a rise in cardiac pumping capacity to meet increased demands, a new UCLA study in rats and mice demonstrates that heart attacks occurring in the last trimester or late months of pregnancy result in worse heart function and more damaged heart tissue than heart attacks among non-pregnant females.
