Guest Post – Page 674 – Shamskm: A site to exchange knowledge and solutions

UMass Amherst Biochemists Trap a Chaperone Machine in Action, Opening Pathway to Possible New Cancer Treatment

By Guest PostJanuary 2, 2013Scienceadp, amino acid chains, anastasia zhuravleva, atp, bacteria, cancer cell, chemical environments, cycle, dnak, drug target, e coli bacteria, Environment, eugenia clerico, folding of proteins, heat shock protein, holding pattern, hsp, hsp70, humans, key step, lila gierasch, massachusetts amherst, mechanism, molecular chaperones, molecular machine, nanofactories, neurodegenerative diseases, nmr methods, nuclear magnetic resonance, origami like, ribosomes, stress, uncontrolled growth, university

AMHERST, Mass. – Molecular chaperones have emerged as exciting new potential drug targets, because scientists want to learn how to stop cancer cells, for example, from using chaperones to enable their uncontrolled growth. Now a team of biochemists at the University of Massachusetts Amherst led by Lila Gierasch have deciphered key steps in the mechanism of the Hsp70 molecular machine by “trapping” this chaperone in action, providing a dynamic snapshot of its mechanism.

She and colleagues describe this work in the current issue of Cell. Gierasch’s research on Hsp70 chaperones is supported by a long-running grant to her lab from NIH’s National Institute for General Medical Sciences. (more…)

Research by CU-Boulder Physicists Creates ‘Recipe Book’ for Building New Materials

By Guest PostJanuary 1, 2013Scienceamherst, bohdan senyuk, China, coffee cup, colloids, colorado boulder, continuously deformed, creation, ivan smalyukh, liquid crystal, liquid crystal displays, materials genome initiative, mathematical theorems, Pennsylvania, president barack obama, qingkun liu, randall kamien, recipe book, robert kusner, sailing he, tiny particle, tom lubensky, topology, university, university of massachusetts, White House, zhejiang university

By showing that tiny particles injected into a liquid crystal medium adhere to existing mathematical theorems, physicists at the University of Colorado Boulder have opened the door for the creation of a host of new materials with properties that do not exist in nature.

The findings show that researchers can create a “recipe book” to build new materials of sorts using topology, a major mathematical field that describes the properties that do not change when an object is stretched, bent or otherwise “continuously deformed.” Published online Dec. 23 in the journal Nature, the study also is the first to experimentally show that some of the most important topological theorems hold up in the real material world, said CU-Boulder physics department Assistant Professor Ivan Smalyukh, a study senior author. (more…)

Targeted Micro-Bubbles Detect Artery Inflammation, MU Study Finds

By Guest PostJanuary 1, 2013Healthanimals, arterial inflammation, artery inflammation, cardio exercise, cause of death, heart disease, human clinical trials, humans, isabelle masseau, leading, michael davis, pigs, plaque, risk for strokes, targeted micro bubbles, ultrasound, university of missouri, world

Procedure done in pigs could potentially detect heart disease early in humans

COLUMBIA, Mo. — Heart disease is a leading cause of death throughout the world. Doctors say that it is important to detect heart disease early before it becomes too serious. Now, researchers at the University of Missouri have found a way that they believe could help detect heart disease before it progresses too far as well as identify patients who are at risk for strokes.

In a study published in Medicine and Science in Sports and Exercise, Isabelle Masseau, an assistant teaching professor in the MU College of Veterinary Medicine, found that she could use targeted micro-bubbles to detect artery inflammation in pigs. She says that this procedure may help detect patients with heart disease or who are at risk for strokes before those ailments become too serious by monitoring artery inflammation, as that is an early warning sign of health problems. She says this procedure may also help monitor the effectiveness of artery inflammation treatments. (more…)

U of T Researchers Uncover Major Source of Evolutionary Differences among Species

By Guest PostJanuary 1, 2013Nature, Sciencealternative splicing, alzheimer, benjamin blencowe, brain, cancer, chicken, chimpanzee, disease, disease susceptibility, frog, fundamental characteristics, fundamental difference, genetic basis, genetic messages, heart, human, human brain, human diseases, identical, liver, mouse, multiple proteins, nuno barbosa morais, set of genes, species, university of toronto, vertebrate, vertebrate evolution

TORONTO, ON – University of Toronto Faculty of Medicine researchers have uncovered a genetic basis for fundamental differences between humans and other vertebrates that could also help explain why humans are susceptible to diseases not found in other species.

Scientists have wondered why vertebrate species, which look and behave very differently from one another, nevertheless share very similar repertoires of genes. For example, despite obvious physical differences, humans and chimpanzees share a nearly identical set of genes. (more…)

UMass Amherst Climate Model is First to Study Climate Effects of Arctic Hurricanes

By Guest PostDecember 31, 2012Environment21st century, alan condron, arctic hurricane, arctic region, arctic seas, barometric pressure, central eye, climate, climate model, climate prediction models, climate scientist, conveyer belt, cyclone, east anglia, England, Europe, forecast climate change, gas exploration, higher resolution modeling, ian renfrew, massachusetts amherst, missing storms, model, North America, north atlantic, norwegian sea, ocean water circulation, oil, oxymoron, polar lows, satellite, thermohaline circulation, thick ice, university, wave

AMHERST, Mass. – Though it seems like an oxymoron, Arctic hurricanes happen, complete with a central “eye,” extreme low barometric pressure and towering 30-foot waves that can sink small ships and coat metal platforms with thick ice, threatening oil and gas exploration. Now climate scientists at the University of Massachusetts Amherst and in England report the first conclusive evidence that Arctic hurricanes, also known as polar lows, play a significant role in driving ocean water circulation and climate.

Results point to potentially cooler conditions in Europe and North America in the 21^st century than other models predict. (more…)

Father’s Death Affects Early Adolescents’ Futures in Developing World, Says MU Anthropologist

By Guest PostDecember 31, 2012Economy, Generaladolescence, bangalore, brooke scelza, child, child outcomes, childhood, data, degree of risk, developing world, educational achievement, effect, evaluation, fathers death, harmful, India, loss of father, mary shenk, measurement tool, needy families, negative effect, offspring success, paternal investment, success in life, united states, university of missouri

Knowledge of effects could lead to better assistance for youths

COLUMBIA, Mo. – A father’s death can have long-term effects on a child’s later success in life and can be particularly harmful if the father passes away during a child’s late childhood or early adolescence, according to new research by a University of Missouri anthropologist. Recognizing the impact that a father’s death can have on adolescents could lead to improved counseling and assistance programs, especially for needy families in the developing world.

“Certain negative effects of a father’s death can’t be compensated for by the mother or other relatives,” said Mary Shenk, assistant professor of anthropology in MU’s College of Arts and Science. “The loss of a father can result in lower adult living standards for the bereaved children. Not only is a child emotionally affected, but the lack of a father’s earning power can cause children to get married younger or drop out of school in order to work.” (more…)

Monkey See, Monkey Do: Visual Feedback Is Necessary for Imitating Facial Expressions

By Guest PostDecember 31, 2012Generalalan johnston, cecilia heyes, chameleon effect, city university london, facial expressions, facial features, facial gestures, imitate, richard cook, target expression, Technology, university college london, university of oxford, visual feedback

Research using new technology shows that our ability to imitate facial expressions depends on learning that occurs through visual feedback.

Studies of the chameleon effect confirm what salespeople, tricksters, and Lotharios have long known: Imitating another person’s postures and expressions is an important social lubricant.

But how do we learn to imitate with any accuracy when we can’t see our own facial expressions and we can’t feel the facial expressions of others? (more…)

Author Archives: Guest Post