Tag Archives: dna sequencing

How Biological Research Can be Transformed

One of the research teams from The University of Texas, Austin, has successfully demonstrated an all-new process of protein sequencing that happens to be more sensitive than the already-existing technology. Moreover, such a way also helps identify molecules of an individual protein, instead of processing a million molecules simultaneously. The new biological advancement proves to be impactful in the field of research. It also makes it efficient and competent enough to disclose the latest biomarkers to diagnose cancer and many other diseases. Furthermore, they also enhance the primary understanding of the way healthy cells function. (more…)

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Worms in space

UD researcher explores effect of zero gravity on genes of microscopic worms

With apologies to the late NASA legend Neil Armstrong, whose boots were the first to step onto the surface of the moon, you might describe Chandran Sabanayagam’s research at the Delaware Biotechnology Institute as one small freefall for a worm, one giant leap for biogenetics. (more…)

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A virus reveals the physics of nanopores

Nanopores could provide a new way to sequence DNA quickly, but the physics involved isn’t well understood. That’s partly because of the complexities involved in studying the random, squiggly form DNA takes in solution. Researchers from Brown have simplified matters by using a stiff, rod-like virus instead of DNA to experiment with nanopores. Their research has uncovered previously unknown dynamics in polymer-nanopore interactions.

PROVIDENCE, R.I. [Brown University] — Nanopores may one day lead a revolution in DNA sequencing. By sliding DNA molecules one at a time through tiny holes in a thin membrane, it may be possible to decode long stretches of DNA at lightning speeds. Scientists, however, haven’t quite figured out the physics of how polymer strands like DNA interact with nanopores. Now, with the help of a particular type of virus, researchers from Brown University have shed new light on this nanoscale physics. (more…)

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Bacteria on your hands reflect the country you live in

Where and how you live strongly influences both the type and number of microbes you carry on your hands, according to a new international study led by scientists at Yale and Stanford.

The research identified and analyzed bacteria on the hands of women in Tanzania and graduate students in the United States, finding that bacterial populations were more similar among the subjects within a country than between subjects of different countries. (more…)

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The final nail in the Jurassic Park coffin

It is hardly possible to talk about fossil insects in amber without the 1993 movie Jurassic Park entering the debate.

The idea of recreating dinosaurs by extracting DNA from insects in amber has held the fascination of the public for two decades. Claims for successful extraction of DNA from ambers up to 130 million-years-old by various scientists in the early 1990s were only seriously questioned when a study at the Natural History Museum, London, was unable to replicate the process. The original claims are now considered by many to be a text-book example of modern contaminant DNA in the samples. Nonetheless, some scientists hold fast to their original claims.

Research just published in the journal The Public Library of Science ONE (PLOS ONE) by a team of researchers from the Faculty of Life Sciences at The University of Manchester can now confirm that the existence of DNA in amber fossils is highly unlikely. The team led by amber expert Dr David Penney and co-ordinated by ancient DNA expert Professor Terry Brown used highly-sensitive ‘next generation’ sequencing techniques – the most advance type of DNA sequencing – on insects in copal, the sub-fossilized resin precursor of amber. (more…)

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Help Wanted: Millions of Cloud-Skilled IT Workers Needed

A study released today by Microsoft and the International Data Corporation (IDC) shows that millions of cloud-related IT jobs are sitting open and millions more will open up in the next two years due to a shortage in cloud-certified IT workers.

REDMOND, Wash. – Dec. 19, 2012 – The information technology forecast for the next two years calls for increasing cloudiness – cloud computing job opportunities, that is.

One in four IT positions worldwide is currently unfilled, and 28 percent of those are cloud-related, according to research [1] released today by the International Data Corporation (IDC). The research also shows that an estimated 1.7 million cloud-related IT jobs are open worldwide right now, and there will be as many as 7 million cloud computing jobs available by 2015. (more…)

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Duplex-sequencing Method Could Lead to Better Cancer Detection and Treatment

During an ice climbing trip to the Canadian Rockies last Christmas, two young researchers from the University of Washington, Drs. Michael Schmitt and Jesse Salk, talked about a simple but powerful idea to get better results when looking at cancer cells. If they could reduce the error rate in DNA sequencing, then researchers could better pinpoint which cells are mutating.

This improvement could lead to early diagnosis of cancer and a better treatment plan once researchers knew which cells were resistant to chemotherapy. (more…)

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Global Bullfrog Trade Spreads Deadly Amphibian Fungus Worldwide

ANN ARBOR, Mich.— The global trade in bullfrogs, which are farmed as a food source in South America and elsewhere, is spreading a deadly fungus that is contributing to the decline of amphibians worldwide, according to a University of Michigan biologist and his colleagues.

Amphibian populations are declining worldwide at an alarming rate, and the spread of the deadly chytrid fungus is believed to be a contributing factor. The fungus infects the skin of frogs, toads and salamanders.

In a study to be published in an upcoming edition of the journal Molecular Ecology, University of Michigan evolutionary biologist Timothy James and his colleagues examine the role of bullfrog farming in spreading the chytrid fungus between the forests and frog farms of Brazil and then to the United States and Japan. (more…)

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