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Chemists Unlock Potential Target For Drug Development

By Guest PostJanuary 22, 2012Scienceadditives, analytical methods, bleeding, blood flow, blood platelets, bloodstream, clotting, cystic fibrosis, dana spence, diabetes, diseases, drug testing, druggable receptors, enzymes, human body, hypertension, michigan state university, molecule, nf449, p2x1, p2y receptor, pharmaceutical target, platelets, receptor, red blood cells, sickle cell anemia

EAST LANSING, Mich. — A receptor found on blood platelets whose importance as a potential pharmaceutical target has long been questioned may in fact be fruitful in drug testing, according to new research from Michigan State University chemists.

A team led by Dana Spence of MSU’s Department of Chemistry has revealed a way to isolate and test the receptor known as P2X1. By creating a new, simple method to study it after blood is drawn, the team has unlocked a potential new drug target for many diseases that impact red blood cells, such as diabetes, hypertension and cystic fibrosis. (more…)

MU Researchers Find Unique Protein Organization in Arteries Associated with Cardiovascular Disease

By Guest PostJanuary 13, 2012Health, Science3 d microscopic imaging technology, amount of protein, artery, artery functions, blood vessels, cardiovascular disease, cause of death, circulatory complications, diabetes, disorders, elastin, elastin production, factor, gerald meininger, high blood pressure, human arteries, michael hill, minute structural elements, molecular biologists, stiffening, stiffening process, tissue replacement proces, united states, university of missouri

*Knowledge could assist in tissue replacements, treatments for high blood pressure and diabetes*

COLUMBIA, Mo. – Human arteries – some smaller than a strand of hair – stiffen as a person ages. This stiffening is a factor in cardiovascular disease, the leading cause of death in the United States, because it contributes to the circulatory complications in disorders such as high blood pressure and diabetes. University of Missouri researchers have now used advanced 3-D microscopic imaging technology to identify and monitor the proteins involved in this stiffening process. These findings could eventually help researchers and physicians understand and treat complications associated with cardiovascular disease. (more…)

CAD for RNA

By Guest PostDecember 27, 2011Scienceaptazyme, biodegradable plastics, biofuels, biological systems, cad, cad platforms, cad type models, cells, computer assisted design, control systems, darmawi juminaga, diabetes, e coli, escherichia coli bacterium, genetic circuits, genetic expression, james carothers, jay keasling, jbei, jonathan goler, lignocellulosic biomass, microbes, microbial fuel production, molecules, parkinson, petrochemicals, ribozyme, rna devices, rna functions, rna molecules, simulations, synberc, synthetic biology, tools, university of california

*Joint BioEnergy Institute Researchers Develop CAD-Type Tools for Engineering RNA Control Systems*

The computer assisted design (CAD) tools that made it possible to fabricate integrated circuits with millions of transistors may soon be coming to the biological sciences. Researchers at the U.S. Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI) have developed CAD-type models and simulations for RNA molecules that make it possible to engineer biological components or “RNA devices” for controlling genetic expression in microbes. This holds enormous potential for microbial-based sustainable production of advanced biofuels, biodegradable plastics, therapeutic drugs and a host of other goods now derived from petrochemicals. (more…)

UA Physician: Diet and Lifestyle Key to Preventing Diabetes

By Guest PostNovember 18, 2011Healthamericans, big benefits, breast cancer and aids, carbohydrate intake, craig stump, diabetes, dietary and physical activity, endocrine specialist, high caloric foods, highly processed carbohydrates, ice cream, obesity, pre diabetic, simple behavior changes, stamina, type 2 diabetes, university of arizona college of medicine tucson, weight loss, white bread, white noodles, white potatoes, white rice

*Dr. Craig Stump, interim director of the Diabetes Research Program at the UA College of Medicine–Tucson, suggests simple behavior changes that can add up to big benefits.*

Diabetes kills more people each year than breast cancer and AIDS combined, and 79 million Americans are at high risk for developing type 2 diabetes, according to the U.S. Centers for Disease Control and Prevention and the American Diabetes Association. (more…)

Preventing Pancreatic Cell Death in Type 1 Diabetes

By Guest PostNovember 9, 2011Healthbeta cell death, blood glucose levels, diabetes, hyperglycemia, insulin producing cells, pancreatic cell death

Diabetes researchers at Yale University have developed a method to detect and measure the destruction of beta cells that occurs in the pancreas by measuring DNA expression in the blood. The destruction of beta cells leads, over time, to type 1 diabetes. Their finding could ultimately lead to a treatment that stops the progression of the disease. The paper appears in the Online Early Edition of the Proceedings of the National Academy of Sciences. (more…)

Even with Regular Exercise, People with Inactive Lifestyles More at Risk for Chronic Diseases, MU Researchers Say

By Guest PostAugust 4, 2011Healthamericans, centers for disease control and prevention, chronic liver condition, diabetes, fatty liver disease, good health, high caloric food, inactive lifestyles, john thyfault, literature, muscle strengthening activity, nafld, new epidemic, nonalcoholic fatty liver disease, obesity, primary cause of chronic diseases, rate of metabolic dysfunction in americans, researchers, scott rector, type 2 diabetes, university of missouri, weekly exercise

COLUMBIA, Mo. – According to the Centers for Disease Control and Prevention, 25 percent of Americans have inactive lifestyles (they take fewer than 5,000 steps a day) and 75 percent do not meet the weekly exercise recommendations (150 minutes of moderate activity each week and muscle-strengthening activity twice a week) to maintain good health. After reviewing recent literature, University of Missouri researchers contend that physical inactivity is the primary cause of chronic diseases such as diabetes, obesity and fatty liver disease and that even people who set aside time for exercise regularly but are otherwise sedentary, may not be active enough to combat these diseases. Inactivity, in addition to the availability of high-caloric food has led to an increased rate of metabolic dysfunction in Americans. (more…)

Tai Chi Helps Prevent Falls and Improves Mental Health in Elderly

By PravdaJuly 19, 2011Healthancient chinese art, balance, british, cardiovascular disease, chinese, diabetes, diseases, effects of tai chi on health, elderly, hypertension, improves mental health, korean, meditative effects, musculoskeletal pain, osteoporosis, parkinson's, philosophy of tai chi, symptoms of cancer or rheumatoid arthritis, tai chi, tai chi master, treatment for fibromyalgia, yang chengfu

Tai Chi helps reduce the risk of falls in the elderly, and improves mental health, is what a new study shows. However, practicing the ancient Chinese art does not help to ease the symptoms of cancer or rheumatoid arthritis.

The information is from the research of a team that analyzed 35 reviews of studies evaluating the effects of Tai Chi on health.

The databases reviewed were British, Chinese and Korean that assessed the impact of Tai Chi on various diseases, including diabetes, hypertension, cancer, osteoarthritis, Parkinson’s, musculoskeletal pain, rheumatoid arthritis, osteoporosis and cardiovascular disease. (more…)

Couples-oriented Programs Found to Boost Healthy Behaviors Among African Americans

By Guest PostMay 17, 2011Healthafrican american couples, antiretroviral therapy, cancer screenings, cardiovascular disease, chronic diseases, diabetes, gail wyatt, haart, healthier eating, hiv and its treatment with haart, hiv medications, hiv-positive, increased physical activity, john b jemmott, nabila el bassel, std risk reduction program, virus, willo pequegnat

*Intervention focuses on couples in which one partner is HIV-positive*

Intervention programs that promote healthier eating, increased physical activity and cancer screenings may be beneficial for African American couples that are at high risk for chronic diseases and that include one partner who is HIV-positive, according to new research.

With such inverventions, each partner appears to draw encouragement from the other to monitor his or her own lifestyle and health, according to study co-author Gail Wyatt, a professor of psychiatry and biobehavioral sciences at the Semel Institute for Neuroscience and Human Behavior at UCLA and an associate director of the UCLA AIDS Institute. (more…)

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