*Analysis questions U.S. Task Force recommendations for every-other-year screening starting at age 50*
ANN ARBOR, Mich. — A new study questions the controversial U.S. Preventative Service Task Force recommendations for breast cancerscreening, with data that shows starting at a younger age and screening more frequently will result in more lives saved.
The study analyzed the same data looked at by the task force, which issued its guidelines on mammography screening in November 2009. The study authors compared the task force’s recommendations for screening every other year in women 50-74 to American Cancer Society guidelines of screening every year in women 40-84.(more…)
Coffee, that morning elixir, may give us an early jump-start to the day, but numerous studies have shown that it also may be protective against type 2 diabetes. Yet no one has really understood why.
Now, researchers at UCLA have discovered a possible molecular mechanism behind coffee’s protective effect. A protein called sex hormone–binding globulin (SHBG) regulates the biological activity of the body’s sex hormones, testosterone and estrogen, which have long been thought to play a role in the development of type 2 diabetes. And coffee consumption, it turns out, increases plasma levels of SHBG. (more…)
A study by Newcastle University in Britain, indicates that green tea may protect the brain from diseases such as Alzheimer’s and other types of dementia. The research, published in the journal Phytomedicine, also suggests that the ancient Chinese remedy that has been popularized throughout the world may also have an important role in protecting the body against cancer.
In the study, scientists investigated whether the beneficial properties of green tea, which had already been proven in newly prepared and undigested tea, were still active once the tea was digested. (more…)
Aspirin - to fight cancer. Image credit: Volker Mintzlaff
Or does it? Fresh research from Oxford University seems to reveal that a low dose of aspirin taken over a substantial period of time produces promising results, indicating that the death rates of many types of cancer reduce greatly. In fact, the evidence presented is staggering and if true, would be a medical breakthrough of exponential proportions.
Let us be optimistic, for cancer is a disease which has cut across most families around the globe. Few of us have not lost a grandparent, parent, uncle or aunt to this disease, in some cases even brothers, or worse still, nephews or nieces…or worse still, sons or daughters, grandsons and daughters. Now it seems there is good news which does not involve chemo-therapy or radio-therapy, which create many success stories but also many victims. (more…)
Dr. Owen Witte, director of the Broad Stem Cell Research Center at UCLA and a Howard Hughes Medical Institute investigator. Image credit: University of California
A protein that is crucial for regulating the self-renewal of normal prostate stem cells, which are needed to repair injured cells or restore normal cells killed by hormone-withdrawal therapy for cancer, also aids the transformation of healthy cells into prostate cancer cells, researchers at UCLA have found.
The findings, by scientists with the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA, may have important implications for controlling cancer growth and progression.
Results from the three-year study, done in primary cells and in animal models, were published Dec. 2 in the early online edition of the peer-reviewed journal Cell Stem Cell.
The protein, called Bmi-1, is often up-regulated, or turned on, in prostate cancer. It has been associated with higher-grade cancers and is predictive of poor prognosis, according to previous studies. However, its functional roles in prostate stem cell maintenance and prostate cancer have been unclear, said the study’s senior author, Dr. Owen Witte, director of the Broad Stem Cell Research Center and a Howard Hughes Medical Institute investigator.(more…)
New research from North Carolina State University shows that most online news stories about cancer contain language that likely contributes to public uncertainty about the disease – a significant finding, given that at least one-third of Americans seek health information online.
“Previous studies show that more than 100 million Americans seek health information online, and that their findings affect their health decisions,” says Dr. Kami Kosenko, an assistant professor of communication at NC State and co-author of a paper describing the study. “But, while people facing uncertainty about cancer issues are likely to seek out additional information, we’ve found that there are features of the information they’re seeking that may actually exacerbate the uncertainty.” (more…)
A model representation of telomerase's RNA "core domain," determined by Juli Feigon, Qi Zhang and colleagues in Feigon's UCLA laboratory. Image credit: Juli Feigon, UCLA Chemistry and Biochemistry/PNAS
Telomerase is an enzyme that maintains the DNA at the ends of our chromosomes, known as telomeres. In the absence of telomerase activity, every time our cells divide, our telomeres get shorter. This is part of the natural aging process, as most cells in the human body do not have much active telomerase. Eventually, these DNA-containing telomeres, which act as protective caps at the ends of chromosomes, become so short that the cells die.
But in some cells, such as cancer cells, telomerase, which is composed of RNA and proteins, is highly active and adds telomere DNA, preventing telomere shortening and extending the life of the cell.
UCLA biochemists have now produced a three-dimensional structural model of the RNA “core domain” of the telomerase enzyme. Because telomerase plays a surprisingly important role in cancer and aging, understanding its structure could lead to new approaches for treating disease, the researchers say.(more…)
Richmond, Va. – If you were dying from cancer, would you consider genetic testing? A recent study conducted by researchers from Virginia Commonwealth University Massey Cancer Centershowed that most terminally ill cancer patients who were eligible for genetic testing never received it despite that it could potentially save a relative’s life.
The research, “Exploring Hereditary Cancer Among Dying Cancer Patients—A Cross-Sectional Study of Hereditary Risk and Perceived Awareness of DNA Testing and Banking,” was recently published in the Journal of Genetic Counseling, and is the first to document the prevalence of hereditary cancer risk and the need for genetic services and patient education among terminally ill cancer patients. (more…)
