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Neuer Wirkstoff hemmt Krebsprotein MYC

By Guest PostAugust 24, 2014Scienceandre maia chagas, anja nohe, best dosage, easton lachappelle, kostenguenstige laborelemente, laborausruestung, osteoporosis treatment, prasad dhurjati, scripps research institute, universitaet innsbruck, unlimited tomorrow, usa, wachstum, wirkstoff

Das Protein MYC ist einer der wichtigsten Faktoren bei der Entstehung von Tumoren im Menschen. Nun haben Wissenschaftler des Scripps Research Institute in den USA und vom Institut für Biochemie der Universität Innsbruck einen neuen Wirkstoff entdeckt, der direkt mit dem MYC-Protein interagiert und das Tumorwachstum stoppen kann.

Das Protein MYC ist entscheidend an der Zellteilung und am Wachstum von Organismen beteiligt. Als Genregulator steuert es die Expression von mindestens 15 Prozent aller menschlichen Gene. Dabei verstärkt es die Expression von wachstums-relevanten Genen. Ist das Myc-Gen verändert und permanent aktiv, kann diese Verstärkung dauerhaft wirken und das Wachstum von Tumoren hervorrufen. Um in der Zelle Gene an- und abschalten zu können, benötigt MYC allerdings einen Partner. Nur wenn es sich mit dem Protein MAX verbindet, kann es an das Erbgut andocken. „Genau hier setzt der neue Wirkstoff an“, sagt Klaus Bister vom Institut für Biochemie der Universität Innsbruck, dessen Arbeitsgruppe gemeinsam mit Forschern des Scripps Research Institute in La Jolla, USA, die neue Substanz und deren Wirkung nun in der amerikanischen Fachzeitschrift Proceedings of the National Academy of Sciences (PNAS) vorstellt. (more…)

NASA’s NuSTAR Sees Rare Blurring of Black Hole Light

By Guest PostAugust 23, 2014Scienceblack hole, black hole coronas, black hole light, gravity

NASA’s Nuclear Spectroscopic Telescope Array (NuSTAR) has captured an extreme and rare event in the regions immediately surrounding a supermassive black hole. A compact source of X-rays that sits near the black hole, called the corona, has moved closer to the black hole over a period of just days. (more…)

Bachnetzwerke regulieren mikrobielle Gemeinschaftsgefüge

By Guest PostAugust 23, 2014Sciencebiodiversitaet, biofilm, blogger cocomadkilla, brand glowrious, cocomadkilla, feng, ferroelectret nanogenerator, mensch, nelson sepulveda, oekosystem, parentalen umwelteffekt, silicone wafer, swiss blogger, umwelt, universitaet wien, wei li

Biofilme im Bachnetzwerk der Ybbs analysiert

Ein interdisziplinäres Forschungsteam rund um den Limnologen Tom J. Battin von der Universität Wien zeigt erstmals, dass die Organisation mikrobieller Lebensgemeinschaften von der Organisation der Umwelt, in der die Mikroorganismen leben, beeinflusst wird. Die WissenschafterInnen sequenzierten dazu die DNA von Biofilmen aus 114 Bächen im Einzugsgebiet der Ybbs und errechneten über Netzwerkanalysen das Gefüge der mikrobiellen Gemeinschaften. Ihre Ergebnisse publizieren sie in der renommierten Fachzeitschrift PNAS. (more…)

Eye movements reveal difference between love and lust

By Guest PostAugust 21, 2014Scienceb all, b lymphozyten, data analyses, data collection, david medgyesi, difference, elmar dolezal, john cacioppo, love, michael reth, romantic love, sexual desire, soul singer, stephanie cacioppo, university of chicago

Soul singer Betty Everett once proclaimed, “If you want to know if he loves you so, it’s in his kiss.” But a new study by University of Chicago researchers suggests the difference between love and lust might be in the eyes after all.

Specifically, where your date looks at you could indicate whether love or lust is in the cards. The new study found that eye patterns concentrate on a stranger’s face if the viewer sees that person as a potential partner in romantic love, but the viewer gazes more at the other person’s body if he or she is feeling sexual desire. That automatic judgment can occur in as little as half a second, producing different gaze patterns. (more…)

Tiniest Catch: UA Scientists’ Fishing Expedition Reveals Viral Diversity in the Sea

By Guest PostAugust 20, 2014Sciencefishing expedition, lab cultured bacteria, ocean viruses, viral tagging

Using bacteria as bait, UA scientists caught wild ocean viruses and found that the genetic lines between virus types in nature are less blurred than previously thought

A fishing expedition of microscopic proportions led by University of Arizona ecologists revealed that the lines between virus types in nature are less blurred than previously thought. (more…)

Printing the Metals of the Future

By Guest PostAugust 18, 2014Science3d print, 3d printing technique, printing metals, printing process

3-D printers can create all kinds of things, from eyeglasses to implantable medical devices, straight from a computer model and without the need for molds. But for making spacecraft, engineers sometimes need custom parts that traditional manufacturing techniques and standard 3-D printers can’t create, because they need to have the properties of multiple metals. Now, researchers at NASA’s Jet Propulsion Laboratory in Pasadena, California, are implementing a printing process that transitions from one metal or alloy to another in a single object. (more…)

Mutation Stops Worms from Getting Drunk

By Guest PostAugust 17, 2014Scienceaustin, caenorhabditis elegans, flotus, gal gadot, indian workforce, jon pierce shimomura, liang wang, nafion, neuroscientist, paralysed arms, potus, real wonder woman, scott davis, skill gap, university of texas, upskilling india

AUSTIN, Texas — Neuroscientists at The University of Texas at Austin have generated mutant worms that do not get intoxicated by alcohol, a result that could lead to new drugs to treat the symptoms of people going through alcohol withdrawal.

The scientists accomplished this feat by inserting a modified human alcohol target into the worms, as reported this week in The Journal of Neuroscience. (more…)

Evolution of a Bimetallic Nanocatalyst

By Guest PostAugust 16, 2014Scienceberkeley lab, christoph heinrich, ehrlichkeit, evolution, evolution of literature, gerhard schroeder, gulf diplomats, haimei zheng, hydrogen gas, joseph dexter, nitrat im grundwasser, oxygen, platinum, poem for mother, pramit chaudhuri, quantitative criticism, reaction, umweltverband wwf

Atomic-scale snapshots of a bimetallic nanoparticle catalyst in action have provided insights that could help improve the industrial process by which fuels and chemicals are synthesized from natural gas, coal or plant biomass. A multi-national lab collaboration led by researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) has taken the most detailed look ever at the evolution of platinum/cobalt bimetallic nanoparticles during reactions in oxygen and hydrogen gases. (more…)

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