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Volunteers Can Now Help Scripps Research Institute Scientists Seek Ebola Cure in Their (Computers’) Spare Time

By Guest PostDecember 3, 2014Health, Technologyaais openidl, aids, andrea graham, cancer, co infections, dengue fever, duerre sommer, influenza, Japan, malaria, naturvertraegliche energiewende, project, sarah budischak, scripps research institute, solving infectious disease, stanley litow, use of blockchain

IBM’s SoftLayer cloud-enabled World Community Grid to provide free virtual supercomputer power to The Scripps Research Institute to speed screening of promising chemical compounds

ARMONK, NY & LA JOLLA, CA – 03 Dec 2014: Although some medical therapies show promise as treatments for Ebola, scientists are still looking urgently for a definitive cure.

For the first time, anyone with access to a computer or Android-based mobile device can help scientists perform this critical research — no financial contribution, passport, or PhD necessary. In fact, volunteers can be asleep, traveling or on a coffee break when they help researchers search for an Ebola cure. (more…)

Neuer Wirkstoff hemmt Krebsprotein MYC

By Guest PostAugust 24, 2014Scienceandre maia chagas, anja nohe, best dosage, easton lachappelle, kostenguenstige laborelemente, laborausruestung, osteoporosis treatment, prasad dhurjati, scripps research institute, universitaet innsbruck, unlimited tomorrow, usa, wachstum, wirkstoff

Das Protein MYC ist einer der wichtigsten Faktoren bei der Entstehung von Tumoren im Menschen. Nun haben Wissenschaftler des Scripps Research Institute in den USA und vom Institut für Biochemie der Universität Innsbruck einen neuen Wirkstoff entdeckt, der direkt mit dem MYC-Protein interagiert und das Tumorwachstum stoppen kann.

Das Protein MYC ist entscheidend an der Zellteilung und am Wachstum von Organismen beteiligt. Als Genregulator steuert es die Expression von mindestens 15 Prozent aller menschlichen Gene. Dabei verstärkt es die Expression von wachstums-relevanten Genen. Ist das Myc-Gen verändert und permanent aktiv, kann diese Verstärkung dauerhaft wirken und das Wachstum von Tumoren hervorrufen. Um in der Zelle Gene an- und abschalten zu können, benötigt MYC allerdings einen Partner. Nur wenn es sich mit dem Protein MAX verbindet, kann es an das Erbgut andocken. „Genau hier setzt der neue Wirkstoff an“, sagt Klaus Bister vom Institut für Biochemie der Universität Innsbruck, dessen Arbeitsgruppe gemeinsam mit Forschern des Scripps Research Institute in La Jolla, USA, die neue Substanz und deren Wirkung nun in der amerikanischen Fachzeitschrift Proceedings of the National Academy of Sciences (PNAS) vorstellt. (more…)

Powerful New Approach to Attack Flu Virus

By Guest PostMay 29, 2012Scienceadaptable virus, avian flu, biopharmaceutical industry, dna deep sequencing, flu epidemics, flu virus, H1N1, H5N1, Israel, kurt stepnitz, la jolla, michigan state university, mutations, nature biotechnology, new approach, pandemic influenza viruses, protein, rehovot, san diego, Science, scripps research institute, smallpox, subtypes, swine flu, therapeutic proteins, tim whitehead, university of washington, weizmann institute

EAST LANSING, Mich. — An international research team has manufactured a new protein that can combat deadly flu epidemics.

The paper, featured on the cover of the current issue of Nature Biotechnology, demonstrates ways to use manufactured genes as antivirals, which disable key functions of the flu virus, said Tim Whitehead, assistant professor of chemical engineering and materials science at Michigan State University.

“Our most potent design has proven effective on the vulnerable sites on many pandemic influenza viruses, including several H1N1 (Spanish flu, Swine flu) and H5N1 (Avian flu) subtypes,” said Whitehead, the paper’s co-lead author. “These new therapeutics are urgently needed, so we were especially pleased to see that it neutralizes H1N1 viruses with potency.” (more…)

Jeopardy! Winnings Spur IBM and Scripps Research Institute Collaboration to Fight Against Malaria

By Guest PostNovember 18, 2011Science, Technologyafrica, alex l perryman, asia, clean water techniques, critical to human health, drug resistant strains, economic distress, go fight against malaria, hiv, human competitors, ibm, jeopardy game, malaria, mike pique, multi drug resistant aids, plasmodium falciparum, renewable energy materials, ruth huey, sargis dallakyan, scripps research institute, south america, stefano forli, subhash sinha, supercomputer of the people, watson computing system, world community grid, world health organization

*Project to use 2 million PCs to crunch numbers, compress 100 years of research into just one*

LA JOLLA, CA and ARMONK, NY – IBM’s Watson computing system broke new ground earlier this year when it defeated two celebrated human competitors on the Jeopardy! game show. Now, The Scripps Research Institute is hoping to do something equally novel but more critical to human health with part of the prize money from that tournament: Find a cure for drug-resistant malaria. And it’s asking for the public’s help.

To that end, Scripps Research and IBM are encouraging anyone in the world with a personal computer to join World Community Grid, a sort of “supercomputer of the people” that will crunch numbers and perform simulations for “GO Fight Against Malaria”—the project that Scripps Research and IBM have launched at https://www.worldcommunitygrid.org. (more…)

Peking University People’s Hospital Partners with IBM to Build China’s First Evidence-Based Patient Centric Care System

By Guest PostJuly 15, 20102 commentsTechnologyChina, chinese, epc3, evidence-based patient centric care, first-of-a-kind, healthcare, her, hiv, ibm, longitudinal, peking university people’s hospital, program, scripps research institute, thomas li

BEIJING – 15 Jul 2010: IBM and Peking University People’s Hospital (People’s Hospital) have built an evidence-based patient centric care (ePC3) system to enable cooperation and resource sharing among medical services providers for improved patient care.

(more…)

Tag Archives: scripps research institute

Volunteers Can Now Help Scripps Research Institute Scientists Seek Ebola Cure in Their (Computers’) Spare Time

Neuer Wirkstoff hemmt Krebsprotein MYC

Powerful New Approach to Attack Flu Virus

Jeopardy! Winnings Spur IBM and Scripps Research Institute Collaboration to Fight Against Malaria

Peking University People’s Hospital Partners with IBM to Build China’s First Evidence-Based Patient Centric Care System