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Mole Crowdsourcing: There could be an App for That

By Guest PostJanuary 1, 2014Healthandy j king, cancerous moles, clinical skin examinations, communication technology, decision-making, douglas grossman, jakob jensen, mole crowdsourcing, pattern, robert w gehl, skin cancer, texas tech university, united states, university of utah

University of Utah researchers identify new technique for identifying cancerous moles

Have you ever had a strange mole on your body and wondered if it was skin cancer? The best move is to schedule an appointment with a dermatologist, but many wait without realizing they could be dealing with melanoma.

Researchers at two universities – the University of Utah and Texas Tech University – have recently identified a new technique for handling this problem: Ask a crowd. (more…)

Many older Americans rely on people, devices, other strategies to get by

By Guest PostDecember 30, 2013Healthadapt to disability, daily life, older americans, public health intervention

ANN ARBOR — Only about a third of Americans ages 65 and older are fully able to take care of themselves and go about their daily lives completely independently, according to a new study published online in the American Journal of Public Health. (more…)

Genetic flaw in males triggers onset of liver cancer, diabetes

By Guest PostDecember 30, 2013Healthchin lee wu, common risk factor, diabetes, diseases, genetic flaw, glucose intolerance, hepatocellular carcinoma, hua xiao, liver cancer, males, mark williams, michigan state university, ncoa5 gene, onset, shenglan gao, therapeutic options, type 2 diabetes

Michigan State University researchers have uncovered a genetic deficiency in males that can trigger the development of one of the most common types of liver cancer and forms of diabetes.

The research, published in the online issue of Cancer Cell, found that when the NCOA5 gene, present in both men and women, was altered in male mice to a deficient level, a spontaneous reaction occurred producing cells that can lead to hepatocellular carcinoma, a type of liver cancer found to be two-to-four times more prevalent in men than women. (more…)

Angelina Jolie Effect: Breast Cancer Awareness vs. Knowledge

By Guest PostDecember 28, 2013Healthangelina jolie effect, breast cancer awareness, breast cancer risk, genetic testing, preventive double mastectomy

COLLEGE PARK, Md. – Angelina Jolie heightened awareness about breast cancer when she announced in a New York Times op-ed that she had undergone a preventive double mastectomy. But a new study led by researchers in the University of Maryland School of Public Health and the Johns Hopkins School of Public Health reveals that widespread awareness of Jolie’s story did not translate into increased understanding of breast cancer risk. (more…)

U.S. ranks near bottom among industrialized nations in efficiency of health care spending

By Guest PostDecember 26, 2013Healthhealth care spending, health care system, health quality, industrialized nations, life expectancy, united states

UCLA, McGill study also shows women fare worse than men in most countries

A new study by researchers at the UCLA Fielding School of Public Health and McGill University in Montreal reveals that the United States health care system ranks 22nd out of 27 high-income nations when analyzed for its efficiency of turning dollars spent into extending lives.
(more…)

High-fat diet during puberty speeds up breast cancer development

By Guest PostDecember 23, 2013Healthadult women, aggressive in nature, basal like, breast cancer development, cell growth, disease, environmental risk factors, experimental model, high fat diet, immune cell, mark aupperlee, michigan state university, precancerous lesions, preclinical model, puberty, research project, richard schwartz, risk of cancer, sandra haslam, tumor

New findings show that eating a high-fat diet beginning at puberty speeds up the development of breast cancer and may actually increase the risk of cancer similar to a type often found in younger adult women.

The research comes from the Breast Cancer and the Environment Research Program at Michigan State University and is published in the current online issue of Breast Cancer Research. (more…)

Database Tracks Toxic Side Effects of Pharmaceuticals

By Guest PostDecember 22, 2013Environment, Healthahmed enayetallah, allan peter davis, chemical toxicity, comparative toxicogenomics database, ctd, daniela sciaky, database, environmental science, gene testing patients, hypertension, jean lay, kelley lennon hopkins, kidney failure, liver disease, north Carolina, novel prediction, pfizer, pharmaceuticals, phenotype module, prediction, project, seizures, state university, thomas wiegers, toxic endpoints, toxic side effects

Sometimes the cure can be worse than the disease. Pharmaceutical drugs are known for their potential side effects, and an important aspect of personalized medicine is to tailor therapies to individuals to reduce the chances of adverse events. Now researchers from North Carolina State University have updated an extensive toxicology database so that it can be used to track information about therapeutic drugs and their unintentional toxic effects.

“Environmental science actually shares a common goal with drug makers: to improve the prediction of chemical toxicity,” says Dr. Allan Peter Davis, lead author of a paper on the work and the biocuration project manager of the Comparative Toxicogenomics Database (CTD) in NC State’s Department of Biological Sciences. (more…)

Zebrafish help decode link between calcium deficiency and colon cancer

By Guest PostDecember 21, 2013Health, Sciencebetween, calcium deficiency, calcium depleted, calcium regulation mechanism, calcium transporter, colon cancer, colon cancer cells, cunming duan, decode, epithelial cell, growth factor, human, link, lisa hebda, low calcium environments, new mechanism, pathway, trpv5, university of michigan, water calcium level, xueping zhong, yan bai, zebrafish, zebrafish embryo skin

ANN ARBOR — A tiny, transparent fish embryo and a string of surprises led scientists to a deeper understanding of the perplexing link between low calcium and colon cancer.

By studying zebrafish embryo skin, University of Michigan researchers decoded cell messages underlying abnormal colonic cell growth of the kind that can lead to tumors and colon cancer in calcium deficient individuals. They have also tested this new mechanism in human colon cancer cells. (more…)

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