Tag Archives: ohio state university

To Cap or Not to Cap: Scientists Find New RNA Phenomenon That Challenges Dogma

COLUMBUS, Ohio – Some RNA molecules spend time in a restful state akin to hibernation rather than automatically carrying out their established job of delivering protein-building instructions in cells, new research suggests.

And instead of being a fluke or a mistake, the research suggests that this restful period appears to be a programmed step for RNA produced by certain types of genes, including some that control cell division and decide where proteins will work in a cell to sustain the cell’s life.

This could mean that protein production in cells is not as clear-cut as biology textbooks suggest, scientists say. (more…)

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“Self-Distancing” Can Help People Calm Aggressive Reactions, Study Finds

COLUMBUS, Ohio – A new study reveals a simple strategy that people can use to minimize how angry and aggressive they get when they are provoked by others.

When someone makes you angry, try to pretend you’re viewing the scene at a distance – in other words, you are an observer rather than a participant in this stressful situation. Then, from that distanced perspective, try to understand your feelings.

Researchers call this strategy “self-distancing.” (more…)

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Practical Tool Can ‘Take Pulse’ of Blue-Green Algae Status in Lakes

COLUMBUS, Ohio – Scientists have designed a screening tool that provides a fast, easy and relatively inexpensive way to predict levels of a specific toxin in lakes that are prone to blue-green algal blooms.

Blue-green algae is not your average pond scum – rather than consisting of plant-like organisms, blue-green algae actually are cyanobacteria, and some species are linked to the production and release of the toxin microcystin into the water. Human exposure to the toxin through drinking or recreational water contact can threaten public health by causing liver damage, neurological problems and gastrointestinal illness in humans. (more…)

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Study: Heart Damage after Chemo Linked to Stress in Cardiac Cells

COLUMBUS, Ohio – Blocking a protein in the heart that is produced under stressful conditions could be a strategy to prevent cardiac damage that results from chemotherapy, a new study suggests.

Previous research has suggested that up to a quarter of patients who receive the common chemotherapy drug doxorubicin are at risk of developing heart failure later in life. Exactly how that heart damage is done remains unclear.

In this study, scientists identified a protein called heat shock factor-1 (HSF-1) as a likely source of chemotherapy-related heart damage in mice and cell cultures. Heat shock factor-1 is known to be induced by stress – in this case, the chemotherapy treatment itself. (more…)

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Statistical Analysis Projects Future Temperatures in North America

COLUMBUS, Ohio – For the first time, researchers have been able to combine different climate models using spatial statistics – to project future seasonal temperature changes in regions across North America.

They performed advanced statistical analysis on two different North American regional climate models and were able to estimate projections of temperature changes for the years 2041 to 2070, as well as the certainty of those projections.

The analysis, developed by statisticians at Ohio State University, examines groups of regional climate models, finds the commonalities between them, and determines how much weight each individual climate projection should get in a consensus climate estimate. (more…)

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“Losing Yourself” in A Fictional Character Can Affect Your Real Life

COLUMBUS, Ohio – When you “lose yourself” inside the world of a fictional character while reading a story, you may actually end up changing your own behavior and thoughts to match that of the character, a new study suggests.

Researchers at Ohio State University examined what happened to people who, while reading a fictional story, found themselves feeling the emotions, thoughts, beliefs and internal responses of one of the characters as if they were their own – a phenomenon the researchers call “experience-taking.” (more…)

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Researchers Find Potential ‘Dark Side’ To Diets High In Beta-Carotene

COLUMBUS, Ohio – New research suggests that there could be health hazards associated with consuming excessive amounts of beta-carotene.

This antioxidant is a naturally occurring pigment that gives color to foods such as carrots, sweet potatoes and certain greens. It also converts to vitamin A, and foods and supplements are the only sources for this essential nutrient.

But scientists at Ohio State University have found that certain molecules that derive from beta-carotene have an opposite effect in the body: They actually block some actions of vitamin A, which is critical to human vision, bone and skin health, metabolism and immune function. (more…)

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Research Shows Why One Bacterial Infection is So Deadly in Cystic Fibrosis

COLUMBUS, Ohio – Scientists have found why a certain type of bacteria, harmless in healthy people, is so deadly to patients with cystic fibrosis.

The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Cystic fibrosis is a chronic disorder characterized by a buildup of mucus in the lungs and other parts of the body, and various types of lung infection are responsible for about 85 percent of deaths in these patients. (more…)

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