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A Second Pathway for Antidepressants: Berkeley Lab Reports New Fluorescent Assay Reveals TREK1 Mechanism

By Guest PostFebruary 25, 2011Scienceantidepressant drugs, berkeley lab, c terminal, cell based fluorescent assay, cytoplasm, ehud isacoff, flow of electrical current, fluorescent protein, fluoxetine, gfp, green fluorescent protein, guillaume sandoz, high speed transistors, human brain, ion channels, membrane, molecular gates, neurons, pharmacological agents, plasma membrane, protein, prozac, sarah bell, transmembrane proteins, trek1, trek1 potassium channel

Using a unique and relatively simple cell-based fluorescent assay they developed, scientists with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC), Berkeley have identified a means by which fluoxetine, the active ingredient in Prozac, suppresses the activity of the TREK1 potassium channel. TREK1 activity has been implicated in mood regulation and could be an important target for fluoxetine and other antidepressant drugs. (more…)

‘Chemical Compounds in Trees Can Fight Deadly Staph Infections in Humans’

By Guest PostFebruary 23, 2011Health, Scienceacne treatment, anti bacterial, antibiotic, bacteria, brian thompson, cash crop, cedar needles, chung ho lin, evolving bacterium, farmers, george stewart, immune systems, key to fighting a deadly bacterium, little economic value, methicillin-resistant, missouri, mrsa, pneumonia, red cedar tree, resistant to most medications, skin, skin cancer, staph infections, staphylococcus aureus, superbug, toxic shock syndrome, trash tree, tree species

COLUMBIA, Mo. – Most people would never suspect that a “trash tree,” one with little economic value and often removed by farmers due to its ability to destroy farmland, could be the key to fighting a deadly bacterium. Now, a University of Missouri researcher has found an antibiotic in the Eastern Red Cedar tree that is effective against methicillin-resistant Staphylococcus aureus (MRSA), a “superbug” that is resistant to most medications.

“I wanted to find a use for a tree species that is considered a nuisance,” said Chung-Ho Lin, research assistant professor in the MU Center for Agroforestry at the College of Agriculture, Food and Natural Resources. “This discovery could help people fight the bacteria as well as give farmers another cash crop.” (more…)

Even in a Crowd, You Remain Unique, UCLA Life Scientists Report

By Guest PostFebruary 23, 2011Sciencea face in the crowd, bigger crowds, crowd, daniel blumstein, evolution of individuality, humans, kimberly pollard, paradoxical, personal uniqueness, rodents, social creatures, social groups, species, the kinks, unique, waldo

“Am I just a face in the crowd? Is that all I’ll ever be? … Do you think I stand out?”

—The Kinks, “A Face in the Crowd”

It may seem paradoxical, but being part of a crowd is what makes you unique, according to UCLA life scientists.

Biologists Kimberly Pollard and Daniel Blumstein examined the evolution of individuality —personal uniqueness — by recording alarm-call vocalizations in eight species of rodents that live in social groups of various sizes. They found that the size of the groups strongly predicted the individual uniqueness in the animals’ voices: The bigger the group, the more unique each animal’s voice typically was and the easier it was to tell individuals apart. (more…)

Global Warming May Reroute Evolution

By Guest PostFebruary 21, 2011Environment, Nature, Scienceasclepias syriaca, asexual reproduction, carbon dioxide levels, cardenolides, chemical defenses, driving force of evolution, elevated carbon dioxide, environmental factors, genetic composition, global warming, heart poisons, interaction, mark hunter, milkweed, milkweed plants, monarch caterpillars, plant eating insects, plant evolution, plants and insects, rachel vannette, selection pressure

ANN ARBOR, Mich.— Rising carbon dioxide levels associated with global warming may affect interactions between plants and the insects that eat them, altering the course of plant evolution, research at the University of Michigan suggests.

The research focused on the effects of elevated carbon dioxide on common milkweed, Asclepias syriaca. Milkweed is one of many plants that produce toxic or bitter chemical compounds to protect themselves from being eaten by insects. These chemical defenses are the result of a long history of interactions between the plants and insects such as monarch caterpillars that feed on them. (more…)

Herschel Measures Dark Matter for Star-Forming Galaxies

By Guest PostFebruary 21, 2011Sciencealexandre amblard, asantha cooray, astronomers, dark matter, distant galaxies, european space agency, exotic substance, Galaxy, herschel, herschel space observatory, jamie bock, longer wavelength infrared light, massive galaxies, Milky Way, Nature, star forming galaxies, stars, telescope, universe, william danchi

PASADENA, Calif. — The Herschel Space Observatory has revealed how much dark matter it takes to form a new galaxy bursting with stars. Herschel is a European Space Agency cornerstone mission supported with important NASA contributions.

The findings are a key step in understanding how dark matter, an invisible substance permeating our universe, contributed to the birth of massive galaxies in the early universe. (more…)

Oldest Fossils of Large Seaweeds, Worm-like Animals Tell Story of Ancient Oxygen

By Guest PostFebruary 20, 2011Sciencealgae and worms, black shale, cambrian explosion, dynamic and complex nature, ediacaran period, Environment, eukaryotes, evolution of life, geochemical data, global ocean, lantian, lantian basin, macrofossils, macroscopic eukaryotes, organic rich black, oxygen, pristine fossils, richard lane, seaweeds, shuhai xiao, snowball earth, south china, virginia tech, xunlai yuan

*Geobiologists uncover Davy Jones Locker of fossils near small village in south China*

Almost 600 million years ago, before the rapid evolution of life forms known as the Cambrian explosion, a community of seaweeds and worm-like animals lived in a quiet deep-water niche near what is now Lantian, a small village in south China.

Then they simply died, leaving some 3,000 nearly pristine fossils preserved between beds of black shale deposited in oxygen-free and unbreathable waters. (more…)

Scientists Build the World’s First Anti-laser

By Guest PostFebruary 20, 2011Scienceanti-laser, coherent light-light waves, gain medium, gallium arsenide, loss medium, near-infrared radiation, optical computing, scientific papers, yale university

More than 50 years after the invention of the laser, scientists at Yale University have built the world’s first anti-laser, in which incoming beams of light interfere with one another in such a way as to perfectly cancel each other out. The discovery could pave the way for a number of novel technologies with applications in everything from optical computing to radiology.

Conventional lasers, which were first invented in 1960, use a so-called “gain medium,” usually a semiconductor like gallium arsenide, to produce a focused beam of coherent light-light waves with the same frequency and amplitude that are in step with one another. (more…)

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