Category Archives: Health

Prostate Cancer Now Detectable Using Imaging-Guided Biopsy, UCLA Study Shows

Groundbreaking research by a team of UCLA physicians and engineers demonstrates that prostate cancer — long identifiable only through painful, hit-or-miss biopsies — can be diagnosed far more easily and accurately using a new image-guided, targeted biopsy procedure. (more…)

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Cognitive Behavioural Therapy Proves Effective at Reducing Depression in People Who Have not Responded to Antidepressants

Antidepressants are the most widely used treatment for people with moderate to severe depression.

However, up to two thirds of people with depression don’t respond fully to this type of treatment. New findings have shown cognitive behavioural therapy (CBT), provided in addition to usual care, can reduce symptoms of depression and help improve patients’ quality of life.

This is the first large-scale trial to test the effectiveness of CBT – a type of talking psychotherapy- given in addition to usual care that includes antidepressants. The National Institute for Health Research Health Technology Assessment (NIHR HTA)-funded CoBalT study aimed to determine the best ‘next step’ treatment for people whose depression had not responded to medication alone. (more…)

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UCLA Doctors Remove Man’s Heart, Replace it with Total Artificial Heart

Portable power supply allows patient to go home while he awaits new heart

Imagine living without a heart. It is possible — if you have a new artificial heart pumping blood through your body. You can even go to the supermarket, watch your kid’s soccer game or go on a hike.

Ronald Reagan UCLA Medical Center has performed its first procedure to remove a patient’s diseased heart and replace it with a SynCardia Temporary Total Artificial Heart.

Chad Washington, 35, underwent the seven-hour transplant surgery at UCLA on Oct. 29, led by Dr. Murray Kwon, an assistant professor of cardiothoracic surgery. (more…)

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Another Muscular Dystrophy Mystery Solved; MU Scientists Inch Closer to a Therapy for Patients

COLUMBIA, Mo. — Approximately 250,000 people in the United States suffer from muscular dystrophy, which occurs when damaged muscle tissue is replaced with fibrous, bony or fatty tissue and loses function. Three years ago, University of Missouri scientists found a molecular compound that is vital to curing the disease, but they didn’t know how to make the compound bind to the muscle cells. In a new study, published in the Proceedings of the National Academies of Science, MU School of Medicine scientists Yi Lai and Dongsheng Duan have discovered the missing pieces to this puzzle that could ultimately lead to a therapy and, potentially, a longer lifespan for patients suffering from the disease.

Duchenne muscular dystrophy (DMD), predominantly affecting males, is the most common type of muscular dystrophy. Patients with Duchenne muscular dystrophy have a gene mutation that disrupts the production of dystrophin, a protein essential for muscle cell survival and function. Absence of dystrophin starts a chain reaction that eventually leads to muscle cell degeneration and death. While dystrophin is vital for muscle development, the protein also needs several “helpers” to maintain the muscle tissue. One of these “helper” molecular compounds is nNOS, which produces nitric oxide that can keep muscle cells healthy after exercise. (more…)

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Bilirubin Can Prevent Damage from Cardiovascular Disease, MU Researchers Find

COLUMBIA, Mo. ­— Each year, about 610,000 Americans suffer their first heart attack, according to the Centers for Disease Control and Prevention. Heart attacks and other symptoms of cardiovascular disease can be caused when blockage occurs in the arteries. In a new study from the University of Missouri, a scientist has discovered a natural defense against arterial blockage: bilirubin.

Bilirubin is typically something parents of newborns hear about when their children are diagnosed with jaundice. Generated during the body’s process to recycle worn-out red blood cells, bilirubin is metabolized by the liver and, usually, leaves the body harmlessly. (Many babies’ livers are not developed enough to metabolize the bilirubin, which results in the infants being diagnosed with jaundice, or high levels of bilirubin in their systems.) Now, MU scientists have found that bilirubin can be used to inhibit the clogging of arteries, and thus prevent the deadly consequences often experienced by individuals with cardiovascular disease. (more…)

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