Author Archives: Guest Post

New Key to Organism Complexity Identified

Berkeley Scientists Find that a Critical Transcription Factor Co-exists in Two Distinct States

The enormously diverse complexity seen amongst individual species within the animal kingdom evolved from a surprisingly small gene pool. For example, mice effectively serve as medical research models because humans and mice share 80-percent of the same protein-coding genes. The key to morphological and behavioral complexity, a growing body of scientific evidence suggests, is the regulation of gene expression by a family of DNA-binding proteins called “transcription factors.” Now, a team of researchers with the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley has discovered the secret behind how one these critical transcription factors is able to perform – a split personality. (more…)

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Engineered Immune Cells Resist Infection from Hiv and Could Ultimately Replace Drug Therapy

AUSTIN, Texas — Researchers at The University of Texas at Austin and the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection from HIV, the virus that causes AIDS. (more…)

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Technology in the Classroom

UD students use iPads to study the presidential election

Ralph Begleiter and Paul Brewer, professors in the University of Delaware’s Department of Communication, wanted to see if students enrolled in their Road to the Presidency class would pay more attention to the presidential election if media were at their fingertips 24/7. Through a UD Information Technologies (IT) Transformation Grant, iPads were distributed to students enrolled in the course.

“There is something about a student laying their finger on the iPad and discovering what event occurred to make a jump in public opinion popularity occur. It’s that interactivity that makes it a personal experience for the student,” Begleiter observed. (more…)

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Keepers of Prometheus: The World’s Oldest Tree

After a nearly 5,000-year vigil upon a Nevada mountaintop, an ancient tree now finds its home in the UA Laboratory of Tree-Ring Research. A member of the long-lived Bristlecone pine species, the tree called Prometheus is the oldest individual ever known to have lived. Its age was not accurately known until a few years ago.

On a craggy, windswept peak in a lonely Nevada wilderness stands a grove of old-growth trees. Gnarled and twisted, shaped by the weather and whirling winds into erratic growth forms, their roots have clung to the pebble-strewn mountainside for literally millennia. (more…)

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UCLA Study First to Image Concussion-Related Abnormal Brain Proteins in Retired NFL Players

Technique may lead to earlier diagnosis, tracking of brain disorders in athletes

Sports-related concussions and mild traumatic brain injuries have grabbed headlines in recent months, as the long-term damage they can cause becomes increasingly evident among both current and former athletes. The Centers for Disease Control and Prevention estimates that millions of these injuries occur each year.

Despite the devastating consequences of traumatic brain injury and the large number of athletes playing contact sports who are at risk, no method has been developed for early detection or tracking of the brain pathology associated with these injuries. (more…)

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IBM and The Institute of Bioengineering and Nanotechnology Develop New Antimicrobial Hydrogel to Fight Superbugs and Drug-Resistant Biofilms

Applications range from protective coating to sterilize hospital surfaces and medical equipment or as an injection to more effectively treat patients

SAN JOSE, Calif. – 24 Jan 2013: Researchers from IBM and the Institute of Bioengineering and Nanotechnology revealed today an antimicrobial hydrogel that can break through diseased biofilms and completely eradicate drug-resistant bacteria upon contact. The synthetic hydrogel, which forms spontaneously when heated to body temperature, is the first-ever to be biodegradable, biocompatible and non-toxic, making it an ideal tool to combat serious health hazards facing hospital workers, visitors and patients.

Traditionally used for disinfecting various surfaces, antimicrobials can be found in traditional household items like alcohol and bleach. However, moving from countertops to treating drug resistant skin infections or infectious diseases in the body are proving to be more challenging as conventional antibiotics become less effective and many household surface disinfectants are not suitable for biological applications. (more…)

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