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Fat cells in breast may connect social stress to breast cancer

By Guest PostJune 23, 2013Healthacaca, acetyl coa carboxykase, acly, aggressive breast cancer, antigen mice, atp citrate lyase, breast, carcinoma in situ, chronic stress, erin wonder, estrogen, fat cells, female mice, gene, her2, hexokinase, hk2, hormones, leptin, lumpectomy, mammary fat, mammary glands, martha mcclintock, matthew brady, maxwell skor, metabolism, metabolism of glucose, multiple tissues, paul volden, progesterone, receptor, social stress, suzanne conzen, sv40 t, triple negative, tumor growth, tumors, university of chicago

Local chemical signals released by fat cells in the mammary gland appear to provide a crucial link between exposure to unrelenting social stressors early in life, and the subsequent development of breast cancer, researchers from the University of Chicago report in the July 2013 issue of the journal Cancer Prevention Research.

Some forms of stress exposure may be associated with an increased risk of certain types of aggressive breast cancer. But the mechanisms linking the biology of social stress to cancer have been hard to identify. To unravel that mechanism, the researchers looked for differences between mice raised in small groups and those that grow up in an isolated setting—an established model of chronic stress without social supports. (more…)

Common Antifungal Drug Decreases Tumor Growth and Shows Promise as Cancer Therapy

By Guest PostAugust 21, 2012Healthantifungal drug, blood vessel growth, cancer therapy, fibrosarcoma tumors, tumor growth

AUSTIN, Texas — An inexpensive antifungal drug, thiabendazole, slows tumor growth and shows promise as a chemotherapy for cancer. Scientists in the College of Natural Sciences at The University of Texas at Austin made this discovery by exploiting the evolutionary relatedness of yeast, frogs, mice and humans. (more…)

Yale Scientists Identify Gene That Controls The Spread of Melanoma

By Guest PostDecember 16, 2011Health, Sciencebeta catenin, braf gene, disease, drug treatments, gene, genetically altered mice, human melanoma, intestine, lungs, lymph nodes, malignant melanoma, manjula santhanakrishnan, marcus w bosenberg, melanoma, metastasis, skin, skin cancer, spleen, tumor growth, william damsky, yale cancer center

Yale Cancer Center researchers have identified a gene in melanoma that can dramatically affect the spread of the disease. The study, published in the journal Cancer Cell, provides new insight into how melanoma metastasizes in patients with advanced disease, and which organs are most likely to be affected. These findings could potentially lead to new drug treatments.

Malignant melanoma is the most deadly form of skin cancer, accounting for 80 percent of all skin cancer deaths. Nearly all melanoma deaths are a result of metastasis, which can occur early in the course of tumor growth in the skin. (more…)

UF Researchers Find Quiet Protein Speaks Loudly in Fight Against Cancer

By Guest PostMay 5, 2011Healthaubrey thompson, brahma, brm, cancer causing genes, cancer inhibiting properties, cancer therapy, carcinogens, cell adhesion, cells, david reisman, dna repair, geoffrey liu, hdac, histone deacetylase, lung cancer, oncogene, protein, race, sex, tumor growth, university of florida, university of toronto

GAINESVILLE, Fla. — When a movie character says, “It’s too quiet,” that’s usually a sign something bad may happen.

Now, University of Florida researchers have discovered that when variations of a certain protein in our cells are too quiet, it may add to the risk that someone will develop lung cancer. When scientists restored the protein to its normal, active self, its cancer-inhibiting properties reappeared. (more…)

Tag Archives: tumor growth

Fat cells in breast may connect social stress to breast cancer

Common Antifungal Drug Decreases Tumor Growth and Shows Promise as Cancer Therapy

Yale Scientists Identify Gene That Controls The Spread of Melanoma

UF Researchers Find Quiet Protein Speaks Loudly in Fight Against Cancer