Tag Archives: standard model

Forcing the Molecular Bond Issue

New and Improved Model of Molecular Bonding from Researchers at Berkeley Lab’s Molecular Foundry

Material properties and interactions are largely determined by the binding and unbinding of their constituent molecules, but the standard model used to interpret data on the formation and rupturing of molecular bonds suffers from inconsistencies. A collaboration of researchers led by a scientist at the U.S Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a first-of-its-kind model for providing a comprehensive description of the way in which molecular bonds form and rupture. This model enables researchers to predict the “binding free energy” of a given molecular system, which is key to predicting how that molecule will interact with other molecules.

“Molecular binding and unbinding events are much simpler than we have been led to believe from the standard model over the past decade,” says Jim DeYoreo, a scientist with the Molecular Foundry, a DOE nanoscience center at Berkeley Lab who was one of the leaders of this research. “With our new model, we now have a clear means for measuring one of the most important parameters governing how materials and molecules bind together.” (more…)

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What’s Happening with the Higgs Boson

Berkeley Lab scientists, major contributors to the ATLAS experiment at the Large Hadron Collider, explain what the excitement is about

CERN, the European Organization for Nuclear Research headquartered in Geneva, Switzerland, will hold a seminar early in the morning on July 4 to announce the latest results from ATLAS and CMS, two major experiments at the Large Hadron Collider (LHC) that are searching for the Higgs boson. Both experimental teams are working down to the wire to finish analyzing their data, and to determine exactly what can be said about what they’ve found.

“We do not yet know what will be shown on July 4th,” says Ian Hinchliffe, a theoretical physicist in the Physics Division at the U.S. Department of Energy’s Lawrence Berkeley National Laboratory (Berkeley Lab), who heads the Lab’s participation in the ATLAS experiment. “I have seen many conjectures on the blogs about what will be shown: these are idle speculation. Things are moving very fast this week, and it’s an exciting time at CERN. Many years of hard work are coming to fruition.” (more…)

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New Take on Impacts of Low Dose Radiation

*Berkeley Lab Researchers Find Evidence Suggesting Risk May Not Be Proportional to Dose at Low Dose Levels*

Researchers with the U.S. Department of Energy (DOE)’s Lawrence Berkeley National Laboratory (Berkeley Lab), through a combination of time-lapse live imaging and mathematical modeling of a special line of human breast cells, have found evidence to suggest that for low dose levels of ionizing radiation, cancer risks may not be directly proportional to dose. This contradicts the standard model for predicting biological damage from ionizing radiation – the linear-no-threshold hypothesis or LNT – which holds that risk is directly proportional to dose at all levels of irradiation.

“Our data show that at lower doses of ionizing radiation, DNA repair mechanisms work much better than at higher doses,” says Mina Bissell, a world-renowned breast cancer researcher with Berkeley Lab’s Life Sciences Division. “This non-linear DNA damage response casts doubt on the general assumption that any amount of ionizing radiation is harmful and additive.” (more…)

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