Tag Archives: red blood cell

Researchers discover hormone that controls supply of iron in red blood cell production

Findings could lead to treatments for blood disorders associated with both iron deficiencies and overloads

A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production.

Iron is an essential functional component of hemoglobin, the molecule that transports oxygen throughout the body. Using a mouse model, researchers found that erythroferrone is made by red blood-cell progenitors in the bone marrow in order to match iron supply with the demands of red blood-cell production. Erythroferrone is greatly increased when red blood-cell production is stimulated, such as after bleeding or in response to anemia. (more…)

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UCLA Scientists Discover ‘Missing Link’ Between Blood Stem Cells, Immune System

UCLA researchers have discovered a type of cell that is the “missing link” between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function.

The research was done using human bone marrow, which contains all the stem cells that produce blood during post-natal life. (more…)

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Pigeons’ Homing Skill Not Down to Iron-Rich Beak Cells

The theory that pigeons’ famous skill at navigation is down to iron-rich nerve cells in their beaks has been disproved by a new study published in Nature.

The study shows that iron-rich cells in the pigeon beak are in fact specialised white blood cells, called macrophages. This finding, which shatters the established dogma, puts the field back on course as the search for magnetic cells continues. (more…)

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