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Common Parasite May Trigger Suicide Attempts

By Guest PostAugust 18, 2012Health, Scienceamerica, biological change, biological mechanism, brain, brain cell, damage, depression, harmless, infection, inflammation, lena brundin, parasite, parkinsons disease, suicide attempt, symptom, t gondii, teodor postolache, toxoplasma gondii, united states

EAST LANSING, Mich. — A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts.

New research appearing in the August issue of The Journal of Clinical Psychiatry adds to the growing work linking an infection caused by the Toxoplasma gondii parasite to suicide attempts. Michigan State University’s Lena Brundin was one of the lead researchers on the team.

About 10-20 percent of people in the United States have Toxoplasma gondii, or T. gondii, in their bodies, but in most it was thought to lie dormant, said Brundin, an associate professor of experimental psychiatry in MSU’s College of Human Medicine. In fact, it appears the parasite can cause inflammation over time, which produces harmful metabolites that can damage brain cells. (more…)

Skin Patch Improves Attention Span in Stroke Patients

By Guest PostJuly 7, 2012Healthadhd, brain damage, drug rotigotine, hemi spatial neglect, masud husain, parkinsons disease, placebo treatment, receptors in brain, skin patch, stroke, stroke patient, ucl, university college london

Researchers at the UCL Institute of Neurology have found that giving the drug rotigotine as a skin patch can improve inattention in some stroke patients.

Hemi-spatial neglect, a severe and common form of inattention that can be caused by brain damage following a stroke, is one of the most debilitating symptoms, frequently preventing patients from living independently. When the right side of the brain has suffered damage, the patient may have little awareness of their left-hand side and have poor memory of objects that they have seen, leaving them inattentive and forgetful. Currently there are few treatment options. (more…)

MSU Researchers Identify Path to Treat Parkinson’s Disease at Its Inception

By Guest PostJanuary 17, 2012Healthalpha synuclein proteins, cellular damage, folding, parkinsons disease

EAST LANSING, Mich. — Imagine if doctors could spot Parkinson’s disease at its inception and treat the protein that triggers it before the disease can sicken the patient. (more…)

New Study to Test Unusual Hypothesis on Beta Brainwaves

By Guest PostDecember 4, 2011Sciencebasal ganglia, beta, beta brainwaves, beta oscillations, brown university, christopher moore, cortex, david orenstein, hypothesis, key brain circuit, model, moore and jones, neurons, neuroscientists, optogenetics, parkinsonian symptoms, parkinsons disease, physical brain, predictions, sensory information, somatosensory system, stephanie jones, thalamocortical circuit, thalamus, touch, touch perception circuit

Beta oscillations are tightly linked to Parkinson’s disease and the ability to process sensory information, such as touch. Two neuroscientists have brought their collaboration to Brown University and won funding from the National Science Foundation to see if they can finally provide a definitive, if unorthodox, explanation for beta brainwaves.

Before she could seek to convince the world that her computer model of a key brain circuit explains a fundamental, 80-year-old mystery of neuroscience with potential relevance to Parkinson’s disease, Stephanie Jones sought to convince Christopher Moore. The new Brown neuroscience professors are now close collaborators, but when they first started talking about the beta oscillations of the cortex, Moore thought Jones was plain wrong, if not a bit nuts. (more…)

“PARKINSONIAN” Worms May Hold The Key to Identifying Drugs for Parkinson’s Disease, Says Scientist

By Guest PostNovember 13, 2011Health, Scienceadela ben yakar, alzheimers, andres vidal gadea, c elegans worms, degenerative disorder of the central nervous system, dopamine deficient worms, dopaminergic systems, early dementia, early symptoms, genetic structure, humans, jon pierce shimomura, layla young, nervous system, neurobiology, neurodegenerative diseases, parkinsonian, parkinsons disease, potential drugs, potential therapeutic, professor, simple test, stephen topper, terrible time, university of texas at austin, worm model

AUSTIN, Texas — Researchers at The University of Texas at Austin have devised a simple test, using dopamine-deficient worms, for identifying drugs that may help people with Parkinson’s disease.

The worms are able to evaluate as many as 1,000 potential drugs a year. The researchers have received federal funding that could increase that to one million drug tests a year. (more…)

Brain Imaging Technique: New Hope for Understanding Parkinson’s Disease

By Guest PostMarch 2, 2011Health, Sciencebasal ganglia, biomedical engineering, brain imaging technique, brain oscillations, disease progression, l dopa, medication, mri, neural oscillations, neurology, parkinsons disease, patients, placebo pill, rachael seidler, radiology, ripple in the pond, scott peltier, symptoms, treatment, youngbin kwak

ANN ARBOR, Mich.— A non-invasive brain imaging technique gives new hope to patients with Parkinson’s disease in finding new and better treatment plans and tracking the disease progression, a new University of Michigan study shows.

The technique uses an MRI to measure resting state brain activity oscillations, said Rachael Seidler, associate professor in the School of Kinesiology and the Department of Psychology, and study author. (more…)

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