UCLA researchers have discovered that some scar-forming cells in the heart, known as fibroblasts, have the ability to become endothelial cells — the cells that form blood vessels. The finding could point the way toward a new strategy for treating people who have suffered a heart attack, because increasing the number of blood vessels in the heart boosts its ability to heal after injury. (more…)
Nicht nur der Mensch altert, sondern auch sein Immunsystem. Wie genau dieser Alterungsprozess abläuft, untersucht die Biomedizinerin Beatrix Grubeck-Loebenstein. Die Immunologin erklärt, warum Impfungen im Alter schlechter funktionieren und was „seneszente“ T-Zellen sind. (more…)
Freiburger Pharmakologen identifizieren Schalter, die für das kardiale Genprogramm eine bedeutende Rolle spielen
Freiburger Pharmakologen haben erstmals das Epigenom von Herzmuskelzellen komplett entschlüsselt. Sie versprechen sich davon unter anderem neue Erkenntnisse über die Entstehung angeborener Herzfehler und der chronischen Herzinsuffizienz. Die Ergebnisse hat das Team in der Fachzeitschrift „Nature Communications“ veröffentlicht. (more…)
ForscherInnen der MFPL liefern wichtige neue Einblicke in Muskelprotein
ForscherInnen um Kristina Djinović-Carugo von den Max F. Perutz Laboratories (MFPL) der Universität Wien und der Medizinischen Universität Wien haben erstmals die molekulare Struktur und Steuerung des lebenswichtigen Muskelproteins α-Actinin aufgeklärt. Die neue Studie erlaubt nie dagewesene Einblicke in die Funktionsweise des Proteins und seine Rolle bei Muskelerkrankungen. Die in Zusammenarbeit mit dem King’s College London (KCL) gewonnen Erkenntnisse, die zu verbesserten Behandlungsmöglichkeiten beitragen können, erscheinen im hochkarätigen Fachjournal Cell. (more…)
Using a recently developed biomarker of aging known as an epigenetic clock, UCLA researchers working closely with a German team of investigators have found for the first time that obesity greatly accelerates aging of the liver. This finding could explain the early onset of many age-related diseases, including liver cancer, in people who are obese. (more…)
IBM’s SoftLayer cloud-enabled World Community Grid to provide free virtual supercomputer power to The Scripps Research Institute to speed screening of promising chemical compounds
ARMONK, NY & LA JOLLA, CA – 03 Dec 2014: Although some medical therapies show promise as treatments for Ebola, scientists are still looking urgently for a definitive cure.
For the first time, anyone with access to a computer or Android-based mobile device can help scientists perform this critical research — no financial contribution, passport, or PhD necessary. In fact, volunteers can be asleep, traveling or on a coffee break when they help researchers search for an Ebola cure. (more…)
For older adults, being unable to identify scents is a strong predictor of death within five years, according to a study published Oct. 1 in the journal PLOS ONE. Thirty-nine percent of study subjects who failed a simple smelling test died during that period, compared to 19 percent of those with moderate smell loss and just 10 percent of those with a healthy sense of smell. (more…)
‘Souped-up’ antibiotics could give doctors an advantage over bacteria that develop immunity to medicines
We face an urgent global health problem because scientists are not developing new antibiotics as fast as bacteria are developing antibiotic resistance. (more…)
