Environmental conditions have a much stronger influence on the mix of microbes living in various parts of your body than does competition between species. Instead of excluding each other, microbes that fiercely compete for similar resources are more likely to cohabit in the same individual.
This phenomenon was discovered in a recent study of the human microbiome – the vast collection of our resident bacteria, fungi, and other tiny organisms. (more…)
In a twist on “survival of the fittest,” researchers have discovered that evolution is driven not by a single beneficial mutation but rather by a group of mutations, including ones called “genetic hitchhikers” that are simply along for the ride. These hitchhikers are mutations that do not appear to have a role in contributing to an organism’s fitness and therefore its evolution, yet may play an important role down the road.
Researchers from Princeton University found in a study of 1,000 generations of adaptation in 40 yeast populations that about five to seven specific mutations, rather than just a one, are needed for an organism to succeed. The knowledge of how mutations drive evolution can inform our understanding of how tumors resist chemotherapeutics and how bacteria evolve resistance to antibiotics. The study was published July 21 in the journal Nature. (more…)
Researchers from North Carolina State University have developed three-dimensional (3-D) printing technology and techniques to create free-standing structures made of liquid metal at room temperature.
“It’s difficult to create structures out of liquids, because liquids want to bead up. But we’ve found that a liquid metal alloy of gallium and indium reacts to the oxygen in the air at room temperature to form a ‘skin’ that allows the liquid metal structures to retain their shapes,” says Dr. Michael Dickey, an assistant professor of chemical and biomolecular engineering at NC State and co-author of a paper describing the work. (more…)
In 2020, a new-generation Mars rover will land on the Red Planet and gather much more detailed data than Curiosity, which is on Mars now. NASA revealed details about the new rover at a news conference Tuesday, July 9, 2013. Brown University’s Jack Mustard chaired the Mars 2020 Science Definition Team.
PROVIDENCE, R.I. [Brown University] — NASA unveiled details about a new roverproposed to land on the surface of Mars in 2020. The details came in the form of a 154-page document prepared by the Mars 2020 Science Definition Team, which was tasked with recommending scientific objectives of the mission. (more…)
Using molecular simulations that modeled a potassium channel and its immediate cellular environment, atom for atom, UChicago scientists have discovered that just 12 molecules of water cause the long post-activation recovery period required by such ion channels before they can function again. The research has revealed a new mechanism in the function of a nearly universal biological structure that will have broad implications, ranging from fundamental biology to the design of pharmaceuticals.
“Our research clarifies the nature of this previously mysterious inactivation state. This gives us better understanding of fundamental biology and should improve the rational design of drugs, which often target the inactivated state of channels,” said Benoît Roux, professor of biochemistry and molecular biology, whose team’s findings were published online July 28 in Nature. (more…)
U.S. Department of Energy national laboratories – including Berkeley Lab – collaborate to build the new magnets CERN needs to increase LHC luminosity by an order of magnitude
The U.S. LHC Accelerator Program (LARP) has successfully tested a powerful superconducting quadrupole magnet that will play a key role in developing a new beam focusing system for CERN’s Large Hadron Collider (LHC). This advanced system, together with other major upgrades to be implemented over the next decade, will allow the LHC to produce 10 times more high-energy collisions than it was originally designed for.
Dubbed HQ02a, the latest in LARP’s series of High-Field Quadrupole magnets is wound with cables of the brittle but high-performance superconductor niobium tin (Nb3Sn). Compared to the final-focus quadrupoles presently in place at the LHC, which are made with niobium titanium, HQ02a has a larger aperture and superconducting coils designed to operate at a higher magnetic field. In a recent test at the Fermi National Accelerator Laboratory (Fermilab), HQ02a achieved all its challenging objectives. (more…)
A University of Colorado Boulder team has developed a radically new technique that uses the power of sunlight to efficiently split water into its components of hydrogen and oxygen, paving the way for the broad use of hydrogen as a clean, green fuel.(more…)
How did life on Earth get started? Three new papers co-authored by Mike Russell, a research scientist at NASA’s Jet Propulsion Laboratory, Pasadena, Calif., strengthen the case that Earth’s first life began at alkaline hydrothermal vents at the bottom of oceans. Scientists are interested in understanding early life on Earth because if we ever hope to find life on other worlds — especially icy worlds with subsurface oceans such as Jupiter’s moon Europa and Saturn’s Enceladus — we need to know what chemical signatures to look for.
Two papers published recently in the journal Philosophical Transactions of the Royal Society B provide more detail on the chemical and precursor metabolic reactions that have to take place to pave the pathway for life. Russell and his co-authors describe how the interactions between the earliest oceans and alkaline hydrothermal fluids likely produced acetate (comparable to vinegar). The acetate is a product of methane and hydrogen from the alkaline hydrothermal vents and carbon dioxide dissolved in the surrounding ocean. Once this early chemical pathway was forged, acetate could become the basis of other biological molecules. They also describe how two kinds of “nano-engines” that create organic carbon and polymers — energy currency of the first cells — could have been assembled from inorganic minerals. (more…)
