Tag Archives: united states

They Know The Drool

*The search for biomarkers of disease in spit*

It’s a researcher’s dream: a simple, noninvasive test to detect life-threatening cancer, heart disease, or other maladies while they’re still treatable.

A team of University of Minnesota researchers is in hot pursuit of that goal, using one of the simplest means imaginable: testing spit. They’ve discovered that conditions such as breast and oral cancer leak certain proteins into saliva, and if detected, such proteins can be “biomarkers” for the disease. (more…)

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Vision Improves Modestly in Patients after Human Embryonic Stem Cells Transplants

Researchers at UCLA’s Jules Stein Eye Institute and colleagues who successfully transplanted specialized retinal cells derived from human embryonic stem cells into the eyes of two legally blind patients report that the transplants appear safe and that both patients have experienced modest improvement in their vision.

The preliminary findings, published online Jan. 23 in the journal The Lancet, represent a milestone in the therapeutic use of stem cells and may pave the way for a new therapy to treat eye diseases, the researchers said. Because this is the first time physicians have applied the power of regenerative medicine to eye disease, the clinical trials are being watched closely by scientists, stem-cell therapy advocates and the public. (more…)

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NASA Sees Repeating La Niña Hitting its Peak

La Niña, “the diva of drought,” is peaking, increasing the odds that the Pacific Northwest will have more stormy weather this winter and spring, while the southwestern and southern United States will be dry.

Sea surface height data from NASA’s Jason-1 and -2 satellites show that the milder repeat of last year’s strong La Niña has recently intensified, as seen in the latest Jason-2 image of the Pacific Ocean, available at: https://sealevel.jpl.nasa.gov/images/ostm/20120108P1.jpg. (more…)

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Clearing a Potential Road Block to Bisabolane

*Joint BioEnergy Institute Researchers Identify Key Enzyme Structure*

The recent discovery that bisabolane, a member of the terpene class of chemical compounds used in fragrances and flavorings, holds high promise as a biosynthetic alternative to D2 diesel fuel has generated keen interest in the green energy community and the trucking industry. Now a second team of researchers with the U.S Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI) has determined the three-dimensional crystal structure of a protein that is key to boosting the microbial-based production of bisabolane as an advanced biofuel.

The JBEI research team, led by bioengineers Paul Adams and Jay Keasling, solved the protein crystal structure of an enzyme in the Grand fir (Abies grandis) that synthesizes bisabolene, the immediate terpene precursor to bisabolane. The performance of this enzyme – the Abies grandis α-bisabolene synthase (AgBIS) – when engineered into microbes, has resulted in a bottleneck that hampers the conversion by the microbes of simple sugars into bisabolene. (more…)

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MU Researchers Find Unique Protein Organization in Arteries Associated with Cardiovascular Disease

*Knowledge could assist in tissue replacements, treatments for high blood pressure and diabetes*

COLUMBIA, Mo. – Human arteries – some smaller than a strand of hair – stiffen as a person ages. This stiffening is a factor in cardiovascular disease, the leading cause of death in the United States, because it contributes to the circulatory complications in disorders such as high blood pressure and diabetes. University of Missouri researchers have now used advanced 3-D microscopic imaging technology to identify and monitor the proteins involved in this stiffening process. These findings could eventually help researchers and physicians understand and treat complications associated with cardiovascular disease. (more…)

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‘Tiger Mothers’ Should Tame Parenting Approach

EAST LANSING, Mich. — The Eastern view of parenting, as defined by best-selling author and self-described “tiger mother” Amy Chua, is that children should be pushed to excel at all costs. Parents needn’t worry about their happiness, she argues, only their success.

But now a Michigan State University scholar is refuting that theory. (more…)

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Russian River Water Unexpected Culprit Behind Arctic Freshening

A hemispherewide phenomenon – and not just regional forces – has caused record-breaking amounts of freshwater to accumulate in the Arctic’s Beaufort Sea.

Frigid freshwater flowing into the Arctic Ocean from three of Russia’s mighty rivers was diverted hundreds of miles to a completely different part of the ocean in response to a decades-long shift in atmospheric pressure associated with the phenomenon called the Arctic Oscillation, according to findings published in the Jan. 5 issue of Nature. (more…)

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Bringing Passito to America

EAST LANSING, Mich. — A Michigan State University researcher is working with vintners to introduce passito, an age-old Italian wine to the United States.

Passito, traced to 800 B.C. in Italy, is also known as straw wine. The grapes for passito are typically hand-picked and allowed to dry on cellar racks or, more traditionally, on mats of straw. (more…)

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