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Targeting Protein Critical To Cell Division Stops Cancer Cells From Proliferating And Kills Them

By Guest PostDecember 18, 2011Scienceanti cancer therapies, apoptosis, biology and metabolism, cancers, cell death, cell division, chemotherapy, chromosome transmission, combination therapy, computational analyses, daughter cells, DNA, drug taxol, dynamic structure, formation of a tumor, function, genetic screen, jorge torres, kinesin like protein, malignant cells, mitosis, mitotic spindle, molecular motor, normal cells, novel strategy, protein, spindle function, stard9, toxic

Suppressing a newly identified protein involved in regulating cell division could be a novel strategy for fighting certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

During the five-year study, designed to seek new targets for anti-cancer therapies, researchers discovered that depleting the protein, called STARD9, also helped the commonly used chemotherapy drug Taxol work more effectively against certain cancers. (more…)

‘Fingerprinting’ Method Tracks Mercury Emissions from Coal-Fired Power Plant

By Guest PostDecember 17, 2011Environmentatmosphere, brains of fetuses, central nervous system, chemical fingerprints, chlorine producing plants, coal, coal combustion, coal fired power plants, coal samples, crystal river, crystal river plant, eastern kentucky, effects on humans, element mercury, environmental pollution, gerald keeler, global atmospheric pool, global mercury reservoir, heart, immune system, incinerators, isotopic fractionation, jason demers, joel blum, laura sherman, mass dependent fractionation, mdf, mercury emissions, mercury emissions in florida, mercury fingerprinting technique, mercury isotope fingerprints, methylmercury, microorganism, natural phenomenon, naturally occurring element, non radioactive, nuclei, power plant, primary source of mercury pollution, protons, rainfall, timothy dvonch, toxic, university of michigan, west virginia

ANN ARBOR, Mich.— For the first time, the chemical “fingerprints” of the element mercury have been used by University of Michigan researchers to directly link environmental pollution to a specific coal-burning power plant.

The primary source of mercury pollution in the atmosphere is coal combustion. The U-M mercury-fingerprinting technique – which has been under development for a decade – provides a tool that will enable researchers to identify specific sources of mercury pollution and determine how much of it is being deposited locally. (more…)

UCLA Scientists Design Experimental Treatment for Iron-Overload Diseases

By Guest PostNovember 6, 2011Health, Scienceamino acids, bo qiao, change in iron flow in the body, cooley anemia, damage, effects of hepcidin in mice, elizabeta nemeth, emilio ramos, excess iron in the body, ferroportin, genetic disorders, gloria c preza, heart, hepcidin, hereditary hemochromatosis, hormone, iron overload, iron overload diseases, iron regulating activity, iron regulation, liver, minihepcidins, molecules, organs, piotr ruchala, therapy, tomas ganz, toxic

Iron overload is a common condition affecting millions of people worldwide. Excess iron in the body is toxic, and deposits can cause damage to the liver, heart and other organs. Current treatments, researchers say, are not ideal and have significant side effects.

Iron in the body is regulated by a hormone called hepcidin, and a deficiency in this hormone can cause the iron overload seen in genetic disorders like hereditary hemochromatosis and Cooley’s anemia. (more…)

Researchers Find That Pollution Forms an Invisible Barrier for Marine Life

By Guest PostMarch 18, 2011Environmentanthropogenic factors, bacteria, chemicals, chlorinated hydrocarbons, coastal areas, coastal water ecosystems, contaminants, discharge, ecosystem based management, evolutionary trajectory, heavy metals, human impacts, human stressors, jon puritz, larvae, los angeles, marine life, municipal treatment plants, nutrients, ocean, pacific coast, petroleum hydrocarbons, plankton, pollutants, population, rob toonen, sea stars, sewage, southern california bight, species, starfish, toxic, united states, urban runoff, urban runoff plumes

Over 50 percent of the population in the United States and over 60 percent in the world live in coastal areas. Rapidly growing human populations near the ocean have massively altered coastal water ecosystems.

One of the most extensive human stressors is the discharge of chemicals and pollutants into the ocean. In the Southern California Bight, more than 60 sewage and urban runoff sources discharge over 1 billion gallons of liquid on a dry day with the two largest sources of contaminants being sewage from municipal treatment plants and urban runoff from highly modified river basins. (more…)

Tag Archives: toxic

Targeting Protein Critical To Cell Division Stops Cancer Cells From Proliferating And Kills Them

‘Fingerprinting’ Method Tracks Mercury Emissions from Coal-Fired Power Plant

UCLA Scientists Design Experimental Treatment for Iron-Overload Diseases

Researchers Find That Pollution Forms an Invisible Barrier for Marine Life