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Researchers Develop System that Finds Prostate Cancer Metastases Earlier

By Guest PostOctober 2, 2011Health, Scienceandrogen deprivation therapy, bone metastasis model, bony metastasis, castration resistant prostate cancer, conventional imaging techniques, gene based imaging system, hormone treatment, jonsson comprehensive cancer center, lily wu, metastatic prostate cancers, oncologists, PET, positron emission tomography scanning, prostate, prostate cancer, prostate specific enhancing sequence, pses, tumor growth rate, ziyue karen jiang

Researchers at UCLA’s Jonsson Comprehensive Cancer Center have developed a way to image the spread of a dangerous form of prostate cancer earlier than today’s conventional imaging techniques. The new method may allow oncologists to find and treat metastases more quickly and give patients a better chance at survival.

The gene-based imaging system targets castration-resistant prostate cancer, an aggressive form of the disease that has become resistant to the hormone treatment known as androgen-deprivation therapy. Once this treatment no longer works, the cancer will progress within 12 to 18 months, and the prognosis becomes grim, said senior study author Dr. Lily Wu, a professor of molecular and medical pharmacology and a Jonsson Cancer Center researcher. (more…)

NASA Leads Study of Unprecedented Arctic Ozone Loss

By Guest PostOctober 2, 2011Science1989 montreal protocol, alfred wegener institute for polar and marine research, amount of ozone, Antarctic, antarctic ozone hole, Arctic, arctic ozone loss, arctic polar vortex, arctic stratospheric temperatures, aura and calipso spacecraft, boulder, canada, chemical ozone destruction, chlorine monoxide, denmark, depletion of earth ozone layer, finland, Germany, gloria manney, Japan, jet propulsion laboratory in pasadena, low temperatures, NASA, new mexico institute of mining and technology in socorro, noaa earth system research laboratory, ozone hole, potsdam, russia, spain, stratosphere, stratospheric ozone layer, the netherlands, ultraviolet rays, united states, winter

PASADENA, Calif. – A NASA-led study has documented an unprecedented depletion of Earth’s protective ozone layer above the Arctic last winter and spring caused by an unusually prolonged period of extremely low temperatures in the stratosphere.

The study, published online Sunday, Oct. 2, in the journal Nature, finds the amount of ozone destroyed in the Arctic in 2011 was comparable to that seen in some years in the Antarctic, where an ozone “hole” has formed each spring since the mid-1980s. The stratospheric ozone layer, extending from about 10 to 20 miles (15 to 35 kilometers) above the surface, protects life on Earth from the sun’s harmful ultraviolet rays. (more…)

MU Researchers Find New Insight into Fatal Spinal Disease

By Guest PostOctober 2, 2011Health, Scienceamyotrophic lateral sclerosis, cells, degeneration of skeletal muscles, duchenne muscular dystrophy, dysfunctions of the synapses, global neurofilament alterations, human disease, jeffrey m dale, michael garcia, motor neurons, protein deficiency, sma, spinal muscular atrophy, system, treatments for muscular dystrophy, university of missouri, virginia garcia

*Discovery could lead to treatments for muscular dystrophy and ALS*

COLUMBIA, Mo. – Researchers at the University of Missouri have identified a communication breakdown between nerves and muscles in mice that may provide new insight into the debilitating and fatal human disease known as spinal muscular atrophy (SMA).

“Critical communication occurs at the point where nerves and muscles ‘talk’ to each other. When this communication between nerves and muscles is disrupted, muscles do not work properly,” said Michael Garcia, associate professor of biological sciences in the College of Arts and Science and the Christopher S. Bond Life Sciences Center. “In this study, we found that delivery of ‘the words’ a nerve uses to communicate with muscles was disrupted before they arrived at the nerve ending.” (more…)

When You Really, Really Have to go: Study Wins Ig Nobel Prize

By Guest PostOctober 2, 2011Entertainment, Scienceig nobel prize, miss sweety poo, scientific humor magazine

Past winners have included scientists who found that asthma symptoms can be treated with a roller coaster ride and veterinarians who reported cows with names give more milk than those without. (more…)

NASA Space Telescope Finds Fewer Asteroids Near Earth

By Guest PostOctober 1, 2011Scienceamy mainzer, asteroids, astronomers, dinosaurs, distant galaxies, jupiter, lindley johnson, mars, NASA, near earth asteroids, neowise, spaceguard, survey project, tim spahr, wide field infrared survey explorer, wise

PASADENA, Calif. –– New observations by NASA’s Wide-field Infrared Survey Explorer, or WISE, show there are significantly fewer near-Earth asteroids in the mid-size range than previously thought. The findings also indicate NASA has found more than 90 percent of the largest near-Earth asteroids, meeting a goal agreed to with Congress in 1998.

Astronomers now estimate there are roughly 19,500 — not 35,000 — mid-size near-Earth asteroids. Scientists say this improved understanding of the population may indicate the hazard to Earth could be somewhat less than previously thought. However, the majority of these mid-size asteroids remain to be discovered. More research also is needed to determine if fewer mid-size objects (between 330 and 3,300-feet wide) also mean fewer potentially hazardous asteroids, those that come closest to Earth. (more…)

‘Heat-proof’ Eggs Help Turtles Cope With Hot Beaches

By Guest PostSeptember 29, 2011Nature, Scienceascension island, cayman islands department of environment, coast of south america, eggs, favourable genes, green turtles, jonathan blount, mark orr, rapid climate change, sam weber, sea turtles, south atlantic ocean, turtle evolution, turtles are naturally heat tolerant, uk, university of exeter, warming climate threatens

*Sea turtles face an uncertain future as a warming climate threatens to reduce their reproductive viability.*

*However, new research led by the University of Exeter and published this week in Proceedings of the Royal Society B shows that some turtles are naturally heat-tolerant.*

The study focused on green turtles nesting on Ascension Island, a UK overseas territory in the South Atlantic Ocean. Scientists from the Universities of Exeter and Groningen found that eggs laid by turtles nesting on a naturally hot beach withstand high temperatures better than eggs from turtles nesting on a cooler beach just a few kilometres away. (more…)

Modified Vaccine Shows Promise in Preventing Malaria

By Guest PostSeptember 29, 2011Health, Scienceandrea amalfitano, barnett rosenberg, circumsporozoite protein, csp, deadly disease, eat 2, gene, gene adjuvants, global effort to prevent malaria infections, hiv, immune response, immune system stimulating gene, key role, malaria parasite, malaria vaccine, michigan state university, nathaniel j schuldt, protein, rea, us army, vaccine, virus, yasser a aldhamen

EAST LANSING, Mich. — Continuing a global effort to prevent malaria infections, Michigan State University researchers have created a new malaria vaccine – one that combines the use of a disabled cold virus with an immune system-stimulating gene – that appears to increase the immune response against the parasite that causes the deadly disease.

At the same time, the group led by Andrea Amalfitano of the College of Osteopathic Medicine also discovered another immune-system stimulating agent – created at MSU and which has been successful in improving immune responses in vaccines for diseases such as HIV – paradoxically made for a less effective malaria vaccine. (more…)

Over the Hump: Ecologists Use Power of Network Science to Challenge Long-Held Theory

By Guest PostSeptember 26, 2011Nature, Sciencealpine tundra, british ecologist, bugle lily, ecologists, effects of environmental change on biodiversity, elizabeth borer, emperor new clothes, global sampling, grime unimodal pattern, habitats, henry gholz, hump shaped model, j philip grime, mt gilboa, national science foundation, peter adler, plant and animal species, productivity of the habitat, scientist, South Africa, utah state university

*Global sampling of 48 sites on five continents yields unprecedented data set*

For decades, ecologists have toiled to nail down principles explaining why some habitats have many more plant and animal species than others.

Much of this debate is focused on the idea that the number of species is determined by the productivity of the habitat.

Shouldn’t a patch of prairie contain a different number of species than an arid steppe or an alpine tundra? (more…)

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