Tag Archives: viral infection

How nanoscience will improve our health and lives in the coming years

Targeted medicine deliveries and increased energy efficiency are just two of many ways

Nanoscience research involves molecules that are only 1/100th the size of cancer cells and that have the potential to profoundly improve the quality of our health and our lives. Now nine prominent nanoscientists look ahead to what we can expect in the coming decade, and conclude that nanoscience is poised to make important contributions in many areas, including health care, electronics, energy, food and water. (more…)

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Our own treacherous immune genes can cause cancer after viral infection

HPV (human papillomavirus) infection is widely known to induce cancer. Many of the mutations that cause this virally-induced cancer are caused by a family of genes that normally combats viral infections, finds new UCL research.

This raises the possibility of developing drugs to regulate the activity of these genes to prevent HPV-associated cancers from developing and reduce the ability of existing cancers to evolve resistance to treatments. (more…)

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IRCM scientists find a novel research model for the study of auto-immune diseases

A team of researchers at the IRCM, led by Dr. Javier M. Di Noia in the Immunity and Viral Infections research division, discovered a novel research model for the study of auto-immune diseases. The Montréal scientists are the first to find a way to separate two important mechanisms that improve the quality of antibodies. This study was featured in a recent issue of The Journal of Immunology.

Dr. Di Noia’s team studies B cells, a group of white blood cells known as lymphocytes whose main function is to produce antibodies to fight against antigens. Antibodies are proteins used by the immune system to identify and neutralize foreign objects (antigens), such as bacteria and viruses, by precisely binding to them, thus making them an essential part of the immune system. Antibodies can come in different varieties (or classes), which perform different roles and adapt the immune response to eliminate each different toxin or pathogen they encounter. The body’s great diversity of antibodies therefore allows the immune system to specifically neutralize an equally wide variety of antigens. (more…)

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UA Scientists Help Discover Most Abundant Ocean Virus

Researchers have discovered four previously unknown viruses that infect the Earth’s most abundant organism, the marine bacterium SAR11. Because of their huge numbers, these tiny players have critical roles in the global cycle of carbon and other nutrients.

The greatest battle in Earth’s history has been going on for hundreds of millions of years, isn’t over yet, and until now no one knew it existed, scientists reported today in the journal Nature.

In one corner is the Earth’s most abundant organism: SAR11, an ocean-living bacterium that survives where most other cells would die and plays a major role in the planet’s carbon cycle. It had been theorized that SAR11 was so small and widespread that it must be invulnerable to attack. (more…)

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Engineered Immune Cells Resist Infection from Hiv and Could Ultimately Replace Drug Therapy

AUSTIN, Texas — Researchers at The University of Texas at Austin and the Stanford University School of Medicine have found a novel way to engineer key cells of the immune system so they remain resistant to infection from HIV, the virus that causes AIDS.

The study, which was published this week in Molecular Therapy, describes the use of a kind of molecular scissors to cut and paste a series of HIV-resistant genes into T cells, specialized immune cells targeted by the virus. (more…)

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Studies: Pigs Look Healthy But Test Positive for Flu at Fairs; Flu Transmission Seen Between Pigs and Humans

COLUMBUS, Ohio – More than 80 percent of pigs that tested positive for influenza A virus at Ohio county fairs between 2009 and 2011 showed no signs of illness, according to a new study.

Ohio State University researchers tested 20 pigs each at 53 fair events over those three summers and found at least one flu-positive pig at 12 fairs – almost a quarter of fairs tested. (more…)

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