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Database Tracks Toxic Side Effects of Pharmaceuticals

By Guest PostDecember 22, 2013Environment, Healthahmed enayetallah, allan peter davis, chemical toxicity, comparative toxicogenomics database, ctd, daniela sciaky, database, environmental science, gene testing patients, hypertension, jean lay, kelley lennon hopkins, kidney failure, liver disease, north Carolina, novel prediction, pfizer, pharmaceuticals, phenotype module, prediction, project, seizures, state university, thomas wiegers, toxic endpoints, toxic side effects

Sometimes the cure can be worse than the disease. Pharmaceutical drugs are known for their potential side effects, and an important aspect of personalized medicine is to tailor therapies to individuals to reduce the chances of adverse events. Now researchers from North Carolina State University have updated an extensive toxicology database so that it can be used to track information about therapeutic drugs and their unintentional toxic effects.

“Environmental science actually shares a common goal with drug makers: to improve the prediction of chemical toxicity,” says Dr. Allan Peter Davis, lead author of a paper on the work and the biocuration project manager of the Comparative Toxicogenomics Database (CTD) in NC State’s Department of Biological Sciences. (more…)

Nanoscale Coatings Improve Stability and Efficiency of Devices for Renewable Fuel Generation

By Guest PostDecember 7, 2013Environment, Scienceaaron k vannucci, acidic, ald, atomic layer deposition, berc kalanyan, carbon dioxide, carbon neutral fuels, chemical pathway, device, efficiency, Environment, gregory parsons, hydrocarbon fuel, hydrogen, klondike bar, leila alibabaei, low ph, mark losego, molecular catalysts, molecular photoelectrochemical cell, nanoscale coatings, north Carolina, oxygen, ph, renewable fuel generation, solar water splitting, stability, state university, ultra thin layer, water oxidation, water splitting devices

Splitting water into its components, two parts hydrogen and one part oxygen, is an important first step in achieving carbon-neutral fuels to power our transportation infrastructure – including automobiles and planes.

Now, North Carolina State University researchers and colleagues from the University of North Carolina at Chapel Hill have shown that a specialized coating technique can make certain water-splitting devices more stable and more efficient. Their results are published online in two separate papers in the Proceedings of the National Academy of Sciences. (more…)

Companies that Screen Social Media Accounts Alienate Job Candidates

By Guest PostDecember 3, 2013Economy, Technologyadam meade, company, facebook account, hypothetical scenario, job applicant, job candidate, lori foster thompson, north Carolina, potential employee, privacy, professionalism, social media, state university, will stoughton

Research from North Carolina State University shows companies that screen the social media accounts of job applicants alienate potential employees – making it harder for them to attract top job candidates. In some cases, social media screening even increases the likelihood that job candidates may take legal action against the offending company.

“The recruiting and selection process is your first indication of how you’ll be treated by a prospective employer,” says Will Stoughton, a Ph.D. student at NC State and lead author of a paper describing the research. “If elite job prospects feel their privacy has been compromised, it puts the hiring company at a competitive disadvantage.” (more…)

Researchers Integrate Single-Crystal BFO onto a Silicon Chip, Open Door to Smart Devices

By Guest PostDecember 1, 2013Sciencebismuth ferrite, data, electronic functions, jay narayan, john prater, magnetic field, magnetic field strength, north Carolina, s rao, silicon chip, single crystal bfo, smart devices, state university, substrate

Researchers from North Carolina State University have for the first time integrated a material called bismuth ferrite (BFO) as a single crystal onto a silicon chip, opening the door to a new generation of multifunctional, smart devices.

BFO has both ferromagnetic and ferroelectric properties, meaning that it can be magnetized by running an electric current through the material. Potential applications for BFO include new magnetic memory devices, smart sensors and spintronics technologies. (more…)

New Technique Controls Dimensions of Gold Nanorods while Manufacturing on a Large Scale

By Guest PostNovember 27, 2013Scienceascorbic acid, cancer treatment, dissolved in solution, gold nanorods, joseph tracy, klaudia kozek, krystian kozek, large scale, nanoscale gold rods, new technique, north Carolina, optical properties, state university, sumeet mishra, vitamin c, wavelengths, wei chen wu

North Carolina State University researchers have a developed a technique for efficiently producing nanoscale gold rods in large quantities while simultaneously controlling the dimensions of the nanorods and their optical properties. The optical properties of gold nanorods make them desirable for use in biomedical applications ranging from imaging technologies to cancer treatment.

“This technique should facilitate the economical manufacture of large volumes of gold nanorods,” says Dr. Joseph Tracy, an associate professor of materials science and engineering at NC State and senior author of a paper on the work. “And that should be good news for both the science community and the biomedical research and development community.” (more…)

Colossal New Predatory Dino Terrorized Early Tyrannosaurs

By Guest PostNovember 24, 2013Nature, Scienceacrocanthosaurus, carcharodontosaur, carnivorous dinosaur, cedar mountain formation, early tyrannosaurs, largest ever discovered, late cretaceous period, lindsay zanno, meeker family, neovenatoridae, new predatory dino, new species, North America, north Carolina, paleontologist, peter makovicky, siats meekerorum, skeleton, small bodied tyrannosaurs, state university, tyrannosaurus rex, utah, ute tribal legend

A new species of carnivorous dinosaur – one of the three largest ever discovered in North America – lived alongside and competed with small-bodied tyrannosaurs 98 million years ago. This newly discovered species, Siats meekerorum, (pronounced see-atch) was the apex predator of its time, and kept tyrannosaurs from assuming top predator roles for millions of years.

Named after a cannibalistic man-eating monster from Ute tribal legend, Siats is a species of carcharodontosaur, a group of giant meat-eaters that includes some of the largest predatory dinosaurs ever discovered. The only other carcharodontosaur known from North America is Acrocanthosaurus, which roamed eastern North America more than 10 million years earlier. Siats is only the second carcharodontosaur ever discovered in North America; Acrocanthosaurus, discovered in 1950, was the first. (more…)

Transgender controversies can lead to ‘gender panic,’ study finds

By Guest PostNovember 6, 2013Culture, Generalanatomically male, binary, female, gender panic, genitalia, grand valley, hormone level, kristen schilt, laurel westbrook, male female gender, moral panic, naturalness, new york city, olympics as women, sex panic, state university, transgender, transgender people, university of chicago, victim, violent crime

When New York City moved in 2006 to make it easier for transgender people to revise the gender on their birth certificates, the proposal was widely expected to pass.

But the anti-discrimination measure failed, in part because of public opposition to removing the requirement that individuals have genital surgery before claiming a different gender. (more…)

Study Finds Natural Compound Can Be Used for 3-D Printing of Medical Implants

By Guest PostNovember 3, 2013Science3d printing, 3d printing technology, alexander nguyen, anastasia koroleva, biocompatible, chapel hill, laser zentrum hannover, medical implants, natural compound, non toxic polymers, nontoxic, north Carolina, photoreactive liquid precursors, riboflavin, roger narayan, shaun gittard, solid polymer, state university, three-dimensional, university, vitamin b2

Researchers from North Carolina State University, the University of North Carolina at Chapel Hill and Laser Zentrum Hannover have discovered that a naturally-occurring compound can be incorporated into three-dimensional (3-D) printing processes to create medical implants out of non-toxic polymers. The compound is riboflavin, which is better known as vitamin B2.

“This opens the door to a much wider range of biocompatible implant materials, which can be used to develop customized implant designs using 3-D printing technology,” says Dr. Roger Narayan, senior author of a paper describing the work and a professor in the joint biomedical engineering department at NC State and UNC-Chapel Hill. (more…)

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