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The final nail in the Jurassic Park coffin

By Guest PostSeptember 16, 2013Sciencecontaminating modern molecules, copal, david penney, dna expert, dna from ambers, dna from insects, dna molecules, dna sequencing, final nail, jurassic park coffin, jurassic park scenario, pcr, polymerase chain reaction, recreating dinosaurs, sub fossilized insects, terry brown, university of manchester

It is hardly possible to talk about fossil insects in amber without the 1993 movie Jurassic Park entering the debate.

The idea of recreating dinosaurs by extracting DNA from insects in amber has held the fascination of the public for two decades. Claims for successful extraction of DNA from ambers up to 130 million-years-old by various scientists in the early 1990s were only seriously questioned when a study at the Natural History Museum, London, was unable to replicate the process. The original claims are now considered by many to be a text-book example of modern contaminant DNA in the samples. Nonetheless, some scientists hold fast to their original claims.

Research just published in the journal The Public Library of Science ONE (PLOS ONE) by a team of researchers from the Faculty of Life Sciences at The University of Manchester can now confirm that the existence of DNA in amber fossils is highly unlikely. The team led by amber expert Dr David Penney and co-ordinated by ancient DNA expert Professor Terry Brown used highly-sensitive ‘next generation’ sequencing techniques – the most advance type of DNA sequencing – on insects in copal, the sub-fossilized resin precursor of amber. (more…)

A SMART(er) Way to Track Influenza

By Guest PostJune 12, 2012Scienceaartik sarma, amplification, andrew artenstein, anubhav tripathi, biological debris, brown assay, brown university, carmichael ong, DNA, first aid kit, flu detection test, genetic sequence, H1N1, hiv, influenza rna, influenza rna sequence, iPhone, magnetics, memorial hospital, microfluidics, nasba, nucleic acid sequence, pigs, polymerase chain reaction, prototype, rhode island, rna partners, rna probe, rna strand, smart, smart detector, stephanie mccalla, steven opal, swine flu, tb, tracking of influenza, tuberculosis, united states, virus in mexico

Brown University researchers have created a reliable and fast flu-detection test that can be carried in a first-aid kit. The novel prototype device isolates influenza RNA using a combination of magnetics and microfluidics, then amplifies and detects probes bound to the RNA. The technology could lead to real-time tracking of influenza. Results are published in the Journal of Molecular Diagnostics.

PROVIDENCE, R.I. [Brown University] — In April 2009, the world took notice as reports surfaced of a virus in Mexico that had mutated from pigs and was being passed from human to human. The H1N1 “swine flu,” as the virus was named, circulated worldwide, killing more than 18,000 people, according to the World Health Organization. The Centers for Disease Control and Prevention in the United States said it was the first global pandemic in more than four decades. (more…)

Innovation Served on a Napkin: How GTRI Moved a Simple Idea From Inspiration to Fabrication

By Guest PostSeptember 3, 2011Science3 d cell, adrenaline, air-conditioning, bloo solar of west sacramento, boeing, boston in 2003, dna replicating process, georgia, georgia tech research institute, gtri, horizon, ip2biz, jack flicker, jud ready, kevlar, larry bawden, micro scale manhattan, microelectronics, nanotechnologies, napkin, octagonal, pcr, polymerase chain reaction, powerpoint presentation, prototypes, solar energy, xcor, yellow jacket flying club

A ground-breaking innovation, birthed in a sudden flash of insight, is the stuff of legend. Air conditioning, Kevlar, the DNA-replicating process known as PCR (polymerase chain reaction) — each was the product of a Eureka! moment. The list may soon be longer by one, thanks to a wandering mind and a napkin.

When Jud Ready attended an academic conference on materials science in Boston in 2003, he didn’t plan on coming home with the idea for a three-dimensional solar cell, but that’s what happened. (more…)

Tag Archives: polymerase chain reaction

The final nail in the Jurassic Park coffin

A SMART(er) Way to Track Influenza

Innovation Served on a Napkin: How GTRI Moved a Simple Idea From Inspiration to Fabrication