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How do we feel pain?

By Guest PostJanuary 24, 2014Healthdose of cannabinoids, hyperalgesia, nerve fibers, pain fibers, pain hypersensitivity, side effects, spinal cord

One day Donald Simone, then a psychology major at Northeastern University, was thumbing through the job listings for work-study students. (more…)

Multiple Sclerosis Study Reveals How Killer T Cells Learn to Recognize Nerve Fiber Insulators

By Guest PostJanuary 12, 2013Healtharsenal, autoimmune disorders, autoimmune encephalitis, autoimmune reactivity, axons, blood vessels, body, brain, branched tentacles, cancer, cd4+ t cell, cd8 t cells, central nervous system, chronic multiple sclerosis, corticosteroids, cytoxic t cells, degeneration of axons, electrical impulse conductors, electrical wire, fight disease, generalized immunosuppressants, humans, infection, inflamed lesions, inflammatory response, inflammatory situation, insulation, joan goverman, killer t cells, laboratory models, lesions, luca castelli, methotrexate, mouse model, multiple sclerosis, myelin protein, myelin sheath, nerve cell projections, nerve fibers, no cells, oligodendrocytes, pathogens, peptides, proteins, qingyong ji, spines, support cells, symptoms, tip dendritic cells, tissue damage, transmit signals, university of washington, white blood cells

Misguided killer T cells may be the missing link in sustained tissue damage in the brains and spines of people with multiple sclerosis, findings from the University of Washington reveal. Cytoxic T cells, also known as CD8+ T cells, are white blood cells that normally are in the body’s arsenal to fight disease.

Multiple sclerosis is characterized by inflamed lesions that damage the insulation surrounding nerve fibers and destroy the axons, electrical impulse conductors that look like long, branching projections. Affected nerves fail to transmit signals effectively. (more…)

Women with Sleep Apnea Have Higher Degree of Brain Damage than Men, UCLA Study Shows

By Guest PostDecember 4, 2012Healthbrain damage, mood regulation, nerve fibers, sleep apnea, white matter, women

Women suffering from sleep apnea have, on the whole, a higher degree of brain damage than men with the disorder, according to a first-of-its-kind study conducted by researchers at the UC LA School o f Nursing. The findings are reported in the December issue of the peer-reviewed journal SLEEP. (more…)

UCLA Researchers Map Damaged Connections in Phineas Gage’s Brain

By Guest PostMay 18, 2012Science1848 case, alzheimer's disease, andrei irimia, arthur w toga, behavioral change, brain, brain disorder, carinna m torgerson, cerebral cortex, computed tomographic data, emotional function, famous case, frontal temporal dementia, gage skull, history, human connectome project, jack van horn, laboratory, limbic structure, loni, mark wheeler, micah c chambers, microscopic links, model, myelin sheath, nerve fibers, neuro imaging, neurons, neuroscience, phineas gage, railroad, rod, san francisco, skull, south america, trajectory, traumatic brain injury, vermont, white matter

Famous 1848 case of man who survived a terrible accident has modern parallel

Poor Phineas Gage. In 1848, the supervisor for the Rutland and Burlington Railroad in Vermont was using a 13-pound, 3-foot-7-inch rod to pack blasting powder into a rock when he triggered an explosion that drove the rod through his left cheek and out of the top of his head. As reported at the time, the rod was later found, “smeared with blood and brains.”

Miraculously, Gage lived, becoming the most famous case in the history of neuroscience — not only because he survived a horrific accident that led to the destruction of much of his left frontal lobe but also because of the injury’s reported effects on his personality and behavior, which were said to be profound. Gage went from being an affable 25-year-old to one that was fitful, irreverent and profane. His friends and acquaintances said he was “no longer Gage.” (more…)

A Whole New Meaning for Thinking on Your Feet

By Guest PostJanuary 9, 2012Natureaxons, biodiversity of spiders, body cavities, brain, brain cells, brain power, brain size and behavior, central nervous systems, costa rica, diameter, energy, genes, genus, hallers rule, human brains, miniaturization, mysmena, nephila clavipes, nerve fibers, nerve signals, nervous system, nucleus, nymphs of spiders, panama, rainforest, rainforest giant, smallest spiders, smithsonian researchers, smithsonian tropical research institute, species of spiders, tiny spiders, tropical ecosystems, tropics, understanding of tropical nature, william wcislo

Smithsonian researchers report that the brains of tiny spiders are so large that they fill their body cavities and overflow into their legs. As part of ongoing research to understand how miniaturization affects brain size and behavior, researchers measured the central nervous systems of nine species of spiders, from rainforest giants to spiders smaller than the head of a pin. As the spiders get smaller, their brains get proportionally bigger, filling up more and more of their body cavities.

“The smaller the animal, the more it has to invest in its brain, which means even very tiny spiders are able to weave a web and perform other fairly complex behaviors,” said William Wcislo, staff scientist at the Smithsonian Tropical Research Institute in Panama. “We discovered that the central nervous systems of the smallest spiders fill up almost 80 percent of their total body cavity, including about 25 percent of their legs.” (more…)

How the Brain Strings Words Into Sentences

By Guest PostNovember 23, 2011Healthbrain imaging, language disorders, language impairments, language processing, nerve fibers, neural pathways

Distinct neural pathways are important for different aspects of language processing, researchers have discovered, studying patients with language impairments caused by neurodegenerative diseases. (more…)

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