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Mystery Solved: How Nerve Impulse Generators Get Where They Need to Go

By Guest PostJanuary 20, 2014Health, Scienceankyrin g, axons, body, brain, cell, central nervous system, chen gu, disease, electrical signaling, joshua barry, key protein, kinesin 1, molecular motor, motor protein, multiple sclerosis, mystery solved, nerve cell bodies, nerve impulse, nerve impulse generators, neurological disorders, neuron, nodes of ranvier, ohio state university, parkinson's, peter jukkola, potassium ion channel, protein, sodium ion channel, spinal cord, symptom, yuanzheng g

Study identifies essential molecule for transport of protein from neuron cell body to axon

COLUMBUS, Ohio – Scientists have solved a longstanding mystery of the central nervous system, showing how a key protein gets to the right spot to launch electrical impulses that enable communication of nerve signals to and from the brain.

Nerve impulses are critical because they are required for neurons to send information about senses, movement, thinking and feeling to other cell types in the neural circuitry. And an impulse is not fired up just once; it is initiated and then must be repeatedly transmitted along axons – long, slender extensions of nerve cell bodies – to keep the nervous system’s messages stable during their rapid travel. (more…)

Tiny Reader Makes Fast, Cheap DNA Sequencing Feasible

By Guest PostMarch 29, 2012Scienceaddiction, adenine, andrew laszlo, cancer, cytosine, diabetes, dna molecule, dna sequencing, elizabeth manrao, enzyme, guanine, ian derrington, jens gundlach, kyle langford, matthew hopper, millisecond, molecular motor, mycobacterium, nanopore, nanoscale sensor, nathaniel gillgren, nucleotide, protein, thymine

Researchers have devised a nanoscale sensor to electronically read the sequence of a single DNA molecule, a technique that is fast and inexpensive and could make DNA sequencing widely available.

The technique could lead to affordable personalized medicine, potentially revealing predispositions for afflictions such as cancer, diabetes or addiction. (more…)

Targeting Protein Critical To Cell Division Stops Cancer Cells From Proliferating And Kills Them

By Guest PostDecember 18, 2011Scienceanti cancer therapies, apoptosis, biology and metabolism, cancers, cell death, cell division, chemotherapy, chromosome transmission, combination therapy, computational analyses, daughter cells, DNA, drug taxol, dynamic structure, formation of a tumor, function, genetic screen, jorge torres, kinesin like protein, malignant cells, mitosis, mitotic spindle, molecular motor, normal cells, novel strategy, protein, spindle function, stard9, toxic

Suppressing a newly identified protein involved in regulating cell division could be a novel strategy for fighting certain cancers because it stops the malignant cells from dividing and causes them to die quickly, according to a study by researchers at UCLA’s Jonsson Comprehensive Cancer Center.

During the five-year study, designed to seek new targets for anti-cancer therapies, researchers discovered that depleting the protein, called STARD9, also helped the commonly used chemotherapy drug Taxol work more effectively against certain cancers. (more…)

Tag Archives: molecular motor

Mystery Solved: How Nerve Impulse Generators Get Where They Need to Go

Tiny Reader Makes Fast, Cheap DNA Sequencing Feasible

Targeting Protein Critical To Cell Division Stops Cancer Cells From Proliferating And Kills Them