Tag Archives: breakthrough

Scientists map elusive 3-D structure of telomerase enzyme, key actor in cancer, aging

Like finally seeing all the gears of a watch and how they work together, researchers from UCLA and UC Berkeley have, for the first time ever, solved the puzzle of how the various components of an entire telomerase enzyme complex fit together and function in a three-dimensional structure.

The creation of the first complete visual map of the telomerase enzyme, which is known to play a significant role in aging and most cancers, represents a breakthrough that could open up a host of new approaches to fighting disease, the researchers said. (more…)

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Breakthrough Technique Images Breast Tumors in 3-D with Great Clarity, Reduced Radiation

Like cleaning the lenses of a foggy pair of glasses, scientists are now able to use a technique developed by UCLA researchers and their European colleagues to produce three-dimensional images of breast tissue that are two to three times sharper than those made using current CT scanners at hospitals. The technique also uses a lower dose of X-ray radiation than a mammogram.

These higher-quality images could allow breast tumors to be detected earlier and with much greater accuracy. One in eight women in the United States will be diagnosed with breast cancer during her lifetime.

The research is published the week of Oct. 22 in the early edition of the journal Proceedings of the National Academy of Sciences. (more…)

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UA Professor Uses Aerospace Materials to Build Endless Green Pipeline

Carbon fiber fabric and lightweight honeycomb materials, plus a mobile manufacturing platform, make infinite pipeline technology cheaper and greener while boosting local economies.

Mo Ehsani, professor emeritus of civil engineering at the University of Arizona, has designed a new, lightweight underground pipe he says could transform the pipeline construction industry.

Instead of conventional concrete or steel, Ehsani’s new pipe consists of a central layer of lightweight plastic honeycomb, similar to that used in the aerospace industry, sandwiched between layers of resin-saturated carbon fiber fabric. (more…)

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Made in IBM Labs: Holey Optochip First to Transfer One Trillion Bits of Information per Second Using the Power of Light

• Researchers invent novel technique by fabricating tiny holes in a single quarter-inch chip to boost data transfer rates
• Until now, it was not possible to transport terabits of data for existing parallel optical communications technology
• New prototype compactly and efficiently delivers ultra-high interconnect bandwidth to power future supercomputer and data center applications

LOS ANGELES – 08 Mar 2012: IBM scientists today will report on a prototype optical chipset, dubbed “Holey Optochip”, that is the first parallel optical transceiver to transfer one trillion bits – one terabit – of information per second, the equivalent of downloading 500 high definition movies. The report will be presented at the Optical Fiber Communication Conference taking place in Los Angeles.

With the ability to move information at blazing speeds – eight times faster than parallel optical components available today – the breakthrough could transform how data is accessed, shared and used for a new era of communications, computing and entertainment. The raw speed of one transceiver is equivalent to the bandwidth consumed by 100,000 users at today’s typical 10 Mb/s high-speed internet access. Or, it would take just around an hour to transfer the entire U.S. Library of Congress web archive through the transceiver. (more…)

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Delving Into Manganite Conductivity

Washington, D.C.— Chemical compounds called manganites have been studied for many years since the discovery of colossal magnetoresistance, a property that promises important applications in the fields of magnetic sensors, magnetic random access memories and spintronic devices. However, understanding—and ultimately controlling—this effect remains a challenge, because much about manganite physics is still not known. A research team lead by Maria Baldini from Stanford University and Carnegie Geophysical Laboratory scientists Viktor Struzhkin and Alexander Goncharov has made an important breakthrough in our understanding of the mysterious ways manganites respond when subjected to intense pressure. (more…)

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Researchers Discover How Key Drug Kills Worms in Tropical Diseases

Charles Mackenzie, a professor of veterinary pathology, works with elephantiasis patients in Tanzania. Image credit: Michigan State University

EAST LANSING, Mich. — In a major breakthrough that comes after decades of research and nearly half a billion treatments in humans, scientists have finally unlocked how a key anti-parasitic drug kills the worms brought on by the filarial diseases river blindness and elephantitis.

Understanding how the drug ivermectin works has the potential to lead to new treatments for the diseases, in which the body is infected with parasitic worms, said Charles Mackenzie, a professor of veterinary pathology in the College of Veterinary Medicine and researcher on the project. The diseases afflict about 140 million people worldwide, doing much of their damage in equatorial Africa.

“Ivermectin is one of the most important veterinary and human anti-parasitic agents ever,” Mackenzie said. “Knowing specifically how it interacts with the body’s own immune system and kills parasitic worms opens up whole new treatment avenues.”

The research appears in the current edition of the Proceedings of the National Academy of Sciences. (more…)

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