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Potassium in brain could be key to fighting Huntington’s disease

By Guest PostApril 26, 2014Healthastrocytes, brain tissue, culture wars, guido buenstorf, huntingtons disease, mark smith, meinung in millisekunden, neurons, rebound effekt, role, secular faith, sparsame technik, stephan bruns, ucla researchers

Researchers were able to improve walking and prolong survival in a mouse model by tweaking potassium levels

By boosting the ability of a specific type of cell to absorb potassium in the brain, UCLA researchers were able to improve walking and prolong survival in a mouse model of Huntington’s disease.

Their findings, published March 30 in the online edition of the journal Nature Neuroscience, could point to new drug targets for treating the devastating disease, which strikes one in every 20,000 Americans. (more…)

Misregulated genes may have big autism role

By Guest PostApril 1, 2013Healthautism, autism cerebral cortex, bank, biochemical exchanges, brain tissue, brains of children, brown university, christianson syndrome, daniel geschwind, endosomes of cells, epilepsy, eric morrow, genetic pathway, human behavior, irinia voineagu, karoly mirnics, key molecular player, krassimira garbett, los angeles, messenger rna, misregulated genes, mutations, nhe6, nhe9, proteins, raw data, statistical analysis, university of california, vanderbilt university

A genetic pathway involving proteins in the endosomes of cells appears to be misregulated in the brains of children with autism, according to a newly published statistical analysis in the journal Molecular Psychiatry. Previously the genes were shown to cause rare forms of the disease but the new study suggests they have a wider role.

PROVIDENCE, R.I. [Brown University] — A new study finds that two genes individually associated with rare autism-related disorders are also jointly linked to more general forms of autism. The finding suggests a new genetic pathway to investigate in general autism research. (more…)

Analysis of Bacterial Genes May Help ID Cause of Dog Brain Disease, Say UF Researchers

By Guest PostOctober 2, 2012Health, Nature, Scienceanalysis, autoimmune, bacteria, balance, brain damage, brain disorder, brain inflammation, brain syndrome, brain tissue, cell, central, chihuahuas, christopher mariani, daniel brown, decreased alertness, dina michaels, disease, dog, florida, gene, genetic makeup, genital tract, gme, granulomatous meningoencephalomyelitis, immune system, karen vernau, macrophages, malteses, mycoplasma canis, necrotizing meningoencephalitis, nervous system, nme, pomeranians, pugs, renee barber, response, scott schatzberg, seizures, small breed, symptom, throat, university, viral agent, virus, yorkshire terriers

GAINESVILLE, Fla. — By analyzing the genes of bacteria, University of Florida researchers have moved a step closer to pinpointing how two brain disorders common in small-breed dogs occur.

The researchers found that the bacteria, known as Mycoplasma canis, invade dog’s cells and suppress their immune system responses. (more…)

Huntington’s Disease

By Guest PostApril 8, 2012Healthalzheimer's disease, amyloid fiber, amyloid seeding assay, asa, brain tissue, david w colby, fluorescent detector, hd, huntingtin, huntingtons disease, monomeric polyglutamine peptide, neurological disease, novel technology, prion disease, protein, sharad gupta, shyann jie, thioflavin t, university of delaware

UD researchers develop novel technique for early detection of misfolded protein

University of Delaware assistant professor David W. Colby is co-author of a paper in the March 23 issue of the Journal of Biological Chemistry that suggests protein misfolding may occur early in the pathogenesis, or development, of Huntington’s disease.

Huntington’s disease (HD) is one of several neurological diseases, such as Alzheimer’s disease or prion disease, associated with proteins that fold into abnormal structures. HD is characterized by progressive motor impairment, cognitive decline and behavioral abnormalities, and ultimately death. (more…)

Tag Archives: brain tissue

Potassium in brain could be key to fighting Huntington’s disease

Misregulated genes may have big autism role

Analysis of Bacterial Genes May Help ID Cause of Dog Brain Disease, Say UF Researchers

Huntington’s Disease